Clinical trials: Metabolic and Bariatric Surgery
Obesity, Type 2 Diabetes Mellitus
Changes in Insulin Sensitivity After Weight Loss
This study is designed to compare the changes in insulin sensitivity as well as gastrointestinal hormone levels in diabetic and non-diabetic obese individuals who are undergoing weight loss procedures.
- Conditions
- Obesity, Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NCT00627484
- Testing
- Gastric bypass, Gastric banding, Sleeve gastrectomy
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity, Bariatric Surgery
Mobile Application for Bariatric Surgery Patients
Introduction: One of the alternative ways, as a result of the increasing demand for health services and the inadequacy of meeting the increasing needs, is mobile health applications.
- Conditions
- Obesity, Bariatric Surgery, Quality of Life, Complication
- Trial name
- NCT05428618
- Testing
- e-BariS app group, Self-Monitoring Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Obesity, Morbid Obesity
Single Anastomosis Versus Standard Duodenal Switch
Bilio-Pancreatic diversion with Duodenal Switch (BPD-DS) is the most effective bariatric procedure in terms of long-term weight loss and remission rate of Type 2 Diabetes.
- Trial name
- SADI (NCT04767490)
- Testing
- Standard Duodenal Switch, Single Anastomosis Duodenal Switch
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Laval University
Obesity
Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery
The goal of this clinical trial is to evaluate the feasibility and acceptability of a 10-wk hybrid Tai Chi (TC) program with in-person classes and online TC videos among 24 physically inactive adults who are seeking metabolic and…
- Trial name
- ACHIEVE (NCT06445413)
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hartford Hospital
Obesity (Disorder)
Continuous Glucose Monitoring in Metabolic Surgery
We will recruit 20 severely obese participants at Metamor Institute. Participants with obesity who are eligible for MBS will be randomized to either CGM group or self-monitoring of blood glucose (SMBG) group before the surgery…
- Trial name
- NCT07095972
- Testing
- Abbot Freestyle Libre CGM
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pennington Biomedical Research Center
Obesity
Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss
It is unknown whether the bile acid pathway reacts differently to weight loss resulting from Roux-En-Y Gastric Bypass (RYGB) surgery than weight loss resulting from caloric restriction alone.
- Trial name
- NCT03238794
- Testing
- Roux-En-Y Gastric Bypass, Low-calorie Diet
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic
Type 2 Diabetes Mellitus, Obesity
Macrovascular and Microvascular Morbidity and Mortality After Metabolic Surgery Versus Medicines
The goal of this study is to compare the impact of metabolic surgery and a class of anti-diabetes medications (Glucagon-like peptide-1 receptor agonists,GLP-1 RAs) on occurrence of diseases involving small and large vessels such…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Microvascular Disease, Macrovascular Disease
- Trial name
- M6 (NCT06355219)
- Volunteers
- 3,932 people
- Sponsor
- Ali Aminian
Obesity
Pilot Behavioral Support Intervention After Bariatric Surgery
Prospective, randomized pilot trial to evaluate a comprehensive postoperative behavioral support intervention using a 4-month bi-weekly program in 40 bariatric surgery patients (all surgical procedure types) from the Geisinger…
- Trial name
- NCT03092479
- Testing
- Behavioral Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Obesity, Diabetes
Pre-operative Intranasal Oxytocin for Enhancing Bariatric-induced Diabetes Remission
This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin in obese adults with diabetes undergoing bariatric surgery.
- Conditions
- Obesity, Diabetes, Bariatric Surgery
- Trial name
- NCT05207774
- Testing
- Oxytocin
- Where
- Israel
- Volunteers
- 3 people
- Sponsor
- Soroka University Medical Center
Weight Loss, Bariatric Surgery Candidate
Resting Metabolic Rate Testing in Bariatric Surgery Patients
This study evaluates if measuring resting metabolic rate (the number of calories the body burns at rest) before surgery can help predict successful weight loss after surgery.
- Trial name
- NCT03221543
- Testing
- ReeVue Indirect Calorimeter
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Morbid Obesity, Hypogonadism
Follow-up of Serum Androgen Profile After Bariatric Surgery in Men With Obesity Related Hypogonadotropic Hypogonadism
The purpose of this study is to determine the natural course of the androgen profile after bariatric surgery in men with obesity related hypogonadotropic hypogonadism.
- Trial name
- NCT00624624
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Rijnstate Hospital
Morbid Obesity
Changes in Incretines, Gut Hormones and Bile Acids After Roux-en-Y Gastric Bypass
Obesity is an increasing world wide problem. Moreover, the increase in patients who are considered morbidly obese is even higher (Sturm et al, Healt Aff 2004).
- Trial name
- NCT03384303
- Testing
- Standardized meal test
- Volunteers
- 10 people
- Sponsor
- Rijnstate Hospital
Obesity
Quality of Life 10 Years After Bariatric Surgery
Importance: Improvement of the QoL after bariatric surgery is an important outcome of the treatment. The investigators believe that assessment of distant QoL results, could provide new insight into effectiveness of most popular…
- Trial name
- Qol-10 (NCT04190459)
- Testing
- LSG, LRYGB
- Where
- Poland
- Volunteers
- 65 people
- Sponsor
- Jagiellonian University
Hepatic Steatosis, Bariatric Surgery Candidate
Hepatic Mitochondrial Function in Youth
Assess the impact of bariatric surgery on hepatic energy metabolism and glucose and insulin dynamics in obese youth
- Conditions
- Hepatic Steatosis, Bariatric Surgery Candidate, Adolescent Obesity, Obesity
- Trial name
- MANGO (NCT03587727)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Obesity
Cyanoacrylate Versus Omentum for Staple-Line Reinforcement in Sleeve Gastrectomy
Study Title: Comparing Surgical Glue (Cyanoacrylate) vs. Omentum Tissue to Strengthen Staple Lines in Weight-Loss Sleeve Surgery What is the purpose of this study? This study will compare two ways to strengthen the staple line…
- Trial name
- NCT07339020
- Testing
- Glubran® 2 surgical glue (n-butyl-2-cyanoacrylate mixture) and its specific applicator., Autologous Greater Omentum, Staple Line Reinforcement during Laparoscopic Sleeve Gastrectomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Obesity, Diabetes Mellitus, Type 2
Bariatric and Metabolic Surgery in Patients Over 65 Years of Age
A retrospective multicenter study that will analyze the results of surgical treatment of obesity in patients over 65 years of age.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- 65plus (NCT06081413)
- Testing
- bariatric surgery
- Where
- Poland
- Volunteers
- 284 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Severe Obesity, Port-Site Hernia
Closure Versus Non-Closure of Working Ports in Laparoscopic Sleeve Gastrectomy
This randomized controlled trial compared closure versus non-closure of the fascia at the working port (trocar) sites during laparoscopic sleeve gastrectomy for severe obesity.
- Conditions
- Severe Obesity, Port-Site Hernia, Postoperative Pain
- Trial name
- NCT07919067
- Testing
- Non-closure of working port fascia (skin closure only), Fascial closure of working ports
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Kasr El Aini Hospital
Obesity
Psychopathology, Disordered Eating, and Impulsivity as Predictors of Outcomes of Bariatric Surgery
This study will evaluate the relationship between psychopathology, disordered eating, and impulsivity (measured by clinical interview, self-report measures, and objective testing) on changes in weight and psychosocial status in…
- Trial name
- SIDE-BAR (NCT02775071)
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
Quality of Life
Prospective Study to Determine Long Term Impact of Bariatric Surgery
The World Health Organization (WHO) statistics, in 2008, there were more than 1.4 billion adults, aged 20 and older, and were overweight. Of these over 200 million men and nearly 300 million women are obese.
- Trial name
- BS-PART2 (NCT02813707)
- Testing
- QoL questionnaire regarding the long term complication
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- United Arab Emirates University
Obesity, Morbid
Single Anastomosis Sleeve Jejunal Bypass as a Revisional Bariatric Procedure
single anastomosis sleeve jejunal bypass as a revisional procedure after weight regain or failure after laparoscopic sleeve gastrectomy, gastric plications or laparoscopic adjustable gastric band
- Trial name
- NCT05269420
- Testing
- SAS-J
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Minia University
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