Clinical trials: Metabolic and Bariatric Surgery
Obesity, Obesity, Abdominal
Laparoscopic Clip-Gastroplasty With The Use Of Bariclip
Sleeve gastrectomy, the most commonly performed bariatric surgery procedure, carries limitations both short-term including postoperative complications such as hemorrhage and gastric fistula and long-term such as weight regain and…
- Conditions
- Obesity, Obesity, Abdominal, Surgery
- Trial name
- B-Clamp (NCT05557084)
- Testing
- laparoscopic vertical clip gastroplasty (LVCG) with Bariclip.
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Rome Tor Vergata
Obesity &Amp; Overweight, Bariatric Surgery
Effects of Concurrent Aerobic and Resistance Training After Bariatric Surgery in Women: RCT
The purpose of this study is to evaluate the effects of a 12-week exercise program on body composition and various physical and physiological parameters in patients who have undergone bariatric surgery.
- Conditions
- Obesity &Amp; Overweight, Bariatric Surgery, Exercise Adaptation
- Trial name
- BARI-EX2023 (NCT07537543)
- Testing
- Aerobicexercise, Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Obesity, Heart Rate Variability
Obesity and Bariatric Surgery According to a Biopsychosocial Perspective.
The main goal of this prospective longitudinal observational study is to investigate the psychophysiological indicators by analyzing HRV, blood pressure, symptoms of anxiety and depression, eating behavior and quality of life…
- Conditions
- Obesity, Heart Rate Variability, Anxiety Disorders, Depression
- Trial name
- NCT05950698
- Testing
- Holter Faros 360° EKG (Bittium Corporation), Beck Depression Inventory (BDI), Hospital Anxiety and Depression Scales - HADS
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Rio de Janeiro State University
Obesity, Bariatric Surgery
Preoperative Treatment With Noninvasive Intra-auricular Vagus Nerve Stimulation Pending Bariatric Surgery
Faced with the current obesity epidemic, new avenues of research into effective weight loss must be developed. Among the possible actions on obesity, vagus nerve stimulation has been shown in several studies to be effective in…
- Trial name
- OBESITE (NCT02648191)
- Testing
- NeuroCoach II Stim
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obesity, Smoking Cessation
A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
The purpose of this research study is to evaluate a multiple health behavior change intervention for weight loss and smoking cessation using medication (Naltrexone + Bupropion) and behavior therapy in adults seeking bariatric…
- Conditions
- Obesity, Smoking Cessation, Bariatric Surgery Patients
- Trial name
- NCT07398404
- Testing
- Naltrexone hydrochloride, Bupropion Hydrochloride Extended-release, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Medical University of South Carolina
Obesity
Effects of Gastric Bypass Surgery on Bile Acid Homeostasis
The purpose of this study is to determine whether the bile acid circulation is changed after gastric bypass surgery. Further, to account for how the changed anatomy of the gut influences how the bile acid and food is mixed in the…
- Trial name
- NCT03475849
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Hypoglycemia, Reactive, Hypoglycemia
Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety After Gastric Surgery
The purpose of this study is to see if the use of a continuous glucose monitor (CGM) by people who experience low blood sugars (hypoglycemia) after gastric surgery can help reduce the number and severity of low blood sugar…
- Trial name
- NCT03353415
- Testing
- Dexcom CGM masked, Dexcom CGM unmasked
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Joslin Diabetes Center
Obesity
A Psychological and Behavioral Intervention for Post-Bariatric Patients
The study is designed to test a pilot intervention for bariatric patients who are starting to regain weight after the 1st year post-surgery.
- Trial name
- NCT01453517
- Testing
- Behavioral intervention for regain after bariatric surgery
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Mayo Clinic
Obesity, Morbid, Weight Regain After Bariatric Surgery
Weight Loss and Comorbidity Outcomes After Revisional Bariatric Surgery
Some people who have had weight-loss (bariatric) surgery do not lose enough weight, regain much of the weight they lost, see obesity-related diseases such as diabetes or high blood pressure return, or develop complications of the…
- Conditions
- Obesity, Morbid, Weight Regain After Bariatric Surgery, Insufficient Weight Loss After Bariatric Surgery, Complication of Bariatric Surgery
- Trial name
- NCT07880691
- Testing
- Revisional bariatric surgery
- Volunteers
- 96 people
- Sponsor
- Kasr El Aini Hospital
Obesity, Periodontitis
Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery
The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions.
- Conditions
- Obesity, Periodontitis, Caries, Periapical Lesion
- Trial name
- NCT00531154
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Loss of Control Eating
Loss of Control Eating Following Weight Loss Surgery
This study will test the effectiveness of two distinct behavioral treatments for loss of control eating following bariatric surgery: 1. Behavioral Weight Loss Treatment 2.
- Trial name
- NCT02259322
- Testing
- Standard-of-Care, Behavioral Weight Loss Treatment, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Obesity, Morbid, Insulin Resistance
Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, Insulin Resistance and Central Reward System
Background: Morbid obesity is associated with decreased brain µ-opioid receptor availability, possibly resulting in higher food intake needed to gain pleasure from eating.
- Trial name
- BariBrainPET (NCT05080205)
- Testing
- Bariatric surgery
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Obesity, Bariatric Surgery
Bariatric Surgery and Sperm Quality
The purpose of this study is to evaluate the impact of a bariatric surgery (gastric banding, bypass, sleeve gastrectomy) on several parameters (quality of sperm and others biological parameters, lifestyle, quality of life)…
- Trial name
- BARIASPERM (NCT01842295)
- Testing
- Blood and sperm samples
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity
Durability of Weight Loss After Bariatric Surgery
The present study is a retrospective cohort study. Patients older than 18 years of age and underwent Roux-en-Y gastric bypass (RYGB) surgical treatment during the period from 2014 to 2019 and paired severely overweight controls…
- Trial name
- NCT04650373
- Testing
- Bariateric surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Obesity, Morbid Obesity
Bariatric Surgery for Morbid Obesity
Despite progress in understanding the pathophysiology of obesity, current strategies for its medical management remain largely ineffective.
- Trial name
- NCT00675558
- Testing
- Initial Surgery, Second Bariatric Surgery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Obesity, Morbid, Diabetes Mellitus, Type 2
Impact of an Increased Restrictive Factor of One Anastomosis Gastric Bypass on Metabolic Outcomes Type 2 Diabetes.
The purpose of the study is to evaluate the effect of an increased restrictive factor of one gastric anastomosis (OAGB) using a "FundoRing" fundoplication on metabolic outcomes in type 2 diabetes mellitus.
- Trial name
- NCT06176443
- Testing
- One anastomosis gastric bypass with combined fundoplication, One anastomosis gastric bypass without combined fundoplication
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Obesity, Bariatric Surgery
Role and Mechanisms of Obesity Surgery
The purpose of this study is to examine how physical activity and lifestyle factors influence postoperative recovery and postoperative complications after bariatric surgery.
- Conditions
- Obesity, Bariatric Surgery, Physical Activity, Post-operative Complications
- Trial name
- RAMOSPHYSSURG (NCT01998815)
- Testing
- Laparoscopic Roux-en-Y gastric bypass surgery
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Göteborg University
Bariatric Surgery Candidate, Bile Acid, Elevated Serum
Metabolic Effects of Endogenous Bile Acids After Gastric Bypass Surgery
Non-randomized, open-label, parallel-group clinical study evaluating the effects of endogenous bile acids on changes in plasma fibroblast growth factor-19 (FGF-19) and glucose metabolism by extended depletion of circulating bile…
- Conditions
- Bariatric Surgery Candidate, Bile Acid, Elevated Serum, Glucose Metabolism Disorders
- Trial name
- Bile-bar (NCT06925997)
- Testing
- Colesevelam
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Hypertension, Obesity
Bariatric Surgery, Arterial Stiffness and Target Organ Damage Study (BASTOD)
Introduction: Obesity is a major public health problem, associated with many morbidities, including metabolic and cardiovascular disease (CVD).
- Trial name
- BASTOD (NCT01494168)
- Testing
- Bariatric surgery (Roux-en-y bypass or sleeve gastrectomy)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Obesity (BMI>30), Obesity (BMI > 35)
FABP4 Response After Roux-en-Y Gastric Bypass
This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months.
- Conditions
- Obesity (BMI>30), Obesity (BMI > 35), Insulin Resistance, Bariatric Surgery
- Trial name
- FABP4-RYGB (NCT07774208)
- Volunteers
- 28 people
- Sponsor
- Istanbul University
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