Clinical trials: Metabolic and Nutritional Disorders
Obesity, Extreme Obesity
Structured Psychoeducation for Unemployed Adolescents With Extreme Obesity in a Multicenter Observational Study Focusing on Feasibility
Obesity occurs more frequently in subjects of a lower socioeconomic status and is associated with a lower income and unemployment.
- Trial name
- STEREOplus (NCT02607995)
- Testing
- Behavioral standardized manual-based multidisciplinary routine care
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Ulm
Obesity
Heart Obesity Prevention Education
Study to collect data on weight management on a male population of retired NFL athletes.
- Trial name
- HOPE (NCT02092545)
- Testing
- Ketogenic diet
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Tampa General Hospital
Xerostomia, Diabetes Mellitus
Photobiomodulation In Treatment Of Xerostomia In Type Ii Diabetic Patients
Xerostomia is a major oral health problem that if not recognized and treated can have a significant effect on a patient's quality of life. It leads to difficulties with speech, swallowing and taste alteration.
- Trial name
- NCT06703372
- Testing
- Diode Laser 980 nm, 0.2W
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hams Hamed Abdelrahman
Obesity
Mindful Eating and Living for Obese Women
Background: Mindfulness-based interventions may be effective in reducing the stress that may increase both obesity and inflammation.
- Trial name
- MEAL (NCT02753972)
- Testing
- Mindful Eating and Living, Active Weight Loss Control
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Heart Failure with Preserved Ejection Fraction, Heart Failure, Diastolic
Impact of Empagliflozin on Functional Capacity in Heart Failure with Preserved Ejection Fraction
Sodium-Glucose Cotransporter-2 (SGLT-2) inhibitors generally and empagliflozin specifically have shown cardiovascular benefits in patients with heart failure (HF), but the underlying mechanisms remain unclear.
- Conditions
- Heart Failure with Preserved Ejection Fraction, Heart Failure, Diastolic, Diabetes Mellitus
- Trial name
- NCT05139472
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity
Improving High School Breakfast Environments
The goals of this intervention study are to implement best practice strategies to expand and promote the school breakfast program and test the impact upon student participation rates among a) all 10th and 11th grade students and…
- Trial name
- breakFAST! (NCT02004977)
- Testing
- Improve access to the school breakfast program
- Where
- United States
- Volunteers
- 904 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
COVID-19, Diabetes Mellitus, Type 2
Study of the Impact of the COVID-19 Pandemic on the Management of Type 2 Diabetic Patients in a Sample in the Paris Region
The Covid-19 crisis is undoubtedly the most significant event of the early 21st century. The pandemic has profoundly changed our way of life, whether as human beings, but also as patients or caregivers.
- Trial name
- DIABETOVID (NCT05175677)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Brittle Type 1 Diabetes Mellitus
Safety, Tolerability, and Efficacy of Immunomodulation With AT-1501 in Combination With Transplanted Islet Cells in Adults With Brittle T1D
This study will evaluate the safety, tolerability and efficacy of AT-1501 in an immunomodulation regimen in adult patients with T1D undergoing an islet cell transplant.
- Trial name
- NCT05480657
- Testing
- AT-1501 IV Infusion, Isolated cadaveric islet cells
- Where
- United States
- Sponsor
- Eledon Pharmaceuticals
Type 2 Diabetes Mellitus, Hypertension (Without Type 2 Diabetes Mellitus)
Empowering Primary Care Providers and Patients to Improve Chronic Disease Outcomes: The EMPOWER Participatory Action Research (EMPOWER - PAR)
BACKGROUND Chronic disease management (CDM) presents enormous challenges to the primary care workforce due to the rising epidemic of cardiovascular risk factors.
- Trial name
- NCT01545401
- Testing
- EMPOWER-PAR Intervention
- Where
- Malaysia
- Volunteers
- 1,545 people
- Sponsor
- Ministry of Health, Malaysia
Cardiovascular Disease
Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy
The objective of this study is to determine the acute and chronic [4-week] effects of a high-DHA fish oil supplement on fasting and post-prandial (post-meal) biomarkers of cardiovascular disease risk, in adults on Statin therapy.
- Trial name
- NCT01690312
- Testing
- Fish Oil
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Type II Diabetes
A Study to Assess the Effect of Food on HR20033 and Pharmacokinetic After Multiple Dose in Healthy Volunteers
According to the objective, the trial is constituted by two study groups: one is food effect assessment group, and another is multiple dose pharmacokinetic assessment group.
- Trial name
- NCT05120219
- Testing
- FDC tablet
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Healthy Volunteers, Dyslipidaemia
A Study to Look at How Safe a New Medicine (NNC0491-6075) is in Healthy People and in Participants With High Levels of Fat in the Blood
The study is testing a new study medicine to treat people with high levels of fat in the blood. The main aim of the study is to see if the new study medicine is safe and how it works in the body.
- Trial name
- NCT05979428
- Testing
- NNC0491-6075
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Wilsons Disease
sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and Fibrosis
The aim is to investigate macrophage activation markers and correlations to liver fibrosis in patients with Wilsons Disease. Researchers wish to investigate associations to neurologic and metabolic liver function.
- Trial name
- NCT02702765
- Testing
- Fibroscan, Ultrasound, Galactose
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- University of Aarhus
Diabetes
Glycemic Response to Six Meal Replacements in Persons With Type 2 Diabetes Mellitus
This will be a randomized, cross-over design. Subjects will be randomized to one of six interventions on six separate study days, 1 week apart.
- Trial name
- NCT03155867
- Testing
- Meal replacement
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Société des Produits Nestlé (SPN)
Nutritional Deficiency, Gastrointestinal Cancers
A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies
This is a randomized, double-blind, placebo-controlled, parallel-group, prospective, multi-center clinical trial, to evaluate the efficacy of silkworm pupa tablets in improving nutritional status and sarcopenia in patients with…
- Conditions
- Nutritional Deficiency, Gastrointestinal Cancers, Sarcopenia
- Trial name
- NCT07554807
- Testing
- Silkworm pupa tablets
- Where
- 4 sites in China
- Volunteers
- 480 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hypercholesterolemia
The Efficacy and Safety of Atorva® 20mg Versus Lipitor® 20mg
The generic formulation of atorvastatin (Atorva®) 20mg was not inferior to the branded formulation of atorvastatin (Lipitor®) 20mg in this 8-week treatment of hyperlipidemic Korean patients.
- Trial name
- NCT01624207
- Testing
- generic formulation of atorvastatin (Atorva®), branded formulation of atorvastatin (Lipitor®)
- Where
- South Korea
- Volunteers
- 376 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus, Type 2, Home Visit
Home-Based Intervention to the Diabetics
Why is the research needed? This study reflects the complexity of the process that patients with diabetes are experiencing when staying at home away from the supervision of health professionals.
- Trial name
- NCT04104711
- Testing
- Home visits, health education
- Volunteers
- 81 people
- Sponsor
- Dilay AÇIL,PhD
Amyotrophic Lateral Sclerosis (ALS)
Remotely Supervised tDCS for Slowing ALS Disease Progression
Most ALS care is centered on patient support and symptom management, making rehabilitation an integral aspect for slowing disease progression, prolonging life span, and increasing quality of life.
- Trial name
- NCT04866771
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Illinois Chicago
Obesity
A Study of RGT001-075 in Participants With Obesity or Overweight With Weight-Related Comorbidities
The main purpose of this study was to evaluate the safety and tolerability of RGT001-075 in healthy participants with obesity
- Trial name
- NCT06277934
- Testing
- RGT001-075
- Where
- 10 sites in United States
- Volunteers
- 73 people
- Sponsor
- Regor Pharmaceuticals Inc.
Polycystic Ovary Syndrome, Insulin Resistance
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
The goal of this interventional study is to assess the effect of drug metformin in improving the fertility hormones and reducing the inflammatory hormones in polycystic ovarian syndrome (PCOS) patients.
- Trial name
- NCT06479434
- Testing
- Metformin
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.