Clinical trials: Metabolic and Nutritional Disorders
Insulin Dependent Diabetes Mellitus 1
Longevity of Multi-Slitted Catheter With Lantern Technology
To determine time to set failure when the Convatec Inset II with Lantern technology (Convatec Lantern) infusion set with multi-slitted catheter is worn for up to 10 days
- Trial name
- Lantern (NCT03819634)
- Testing
- Inset II with Lantern Technology
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Metabolic Syndrome
Effect of a High-Protein Diet and/or High-Intensity Training on Metabolic Syndrome
The objective of this study is to determine the combined effects of a high-protein diet and high-intensity training on metabolic syndrome risk factors in women aged 30-65.
- Trial name
- EPHIT (NCT01622634)
- Testing
- Sprint Interval Exercise, Higher PRO Diet, Higher CARB Diet
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Insulin Resistance, Prediabetic State
Impact of Digital Therapeutic on Metabolic Parameters
The purpose of this prospective randomized controlled study is to evaluate the impact of a six-month digitally administered behavioral change program on body weight, glycemic control and other metabolic parameters in obese adults…
- Conditions
- Insulin Resistance, Prediabetic State, Diabetes Mellitus, Type 2, Obesity
- Trial name
- NCT04573296
- Testing
- Vitadio, Conventional high-intensity lifestyle intervention program
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Vitadio s.r.o.
Cardiovascular Risk Factor
Choline and Cardiometabolic Health
Trimethylamine-N-oxide (TMAO), a metabolite produced by gut microbial metabolism of dietary choline, has recently been causally linked to atherosclerosis in animal models and has been shown to be predictive of cardiovascular…
- Trial name
- NCT04764162
- Testing
- Choline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Gaucher Disease
Nutritional Status of Gaucher Disease Patients
This cross-sectional study aims to evaluate the nutritional status of patients with Gaucher disease attending Assiut University Children's Hospital using anthropometric measurements and body composition analysis.
- Trial name
- NCT07845188
- Volunteers
- 84 people
- Sponsor
- Assiut University
Obesity
Interdisciplinary Intervention in Patients With Obesity and Other Metabolic Diseases
The aim of the research study will be assess the effectiveness of a long-term interdisciplinary lifestyle in many aspects including food intake, psychological symptoms, physical activity habits, energy expenditure, body…
- Trial name
- NCT02573688
- Testing
- Interdisciplinary Therapy
- Where
- Brazil
- Volunteers
- 87 people
- Sponsor
- Federal University of São Paulo
Type 1 Diabetes
Kids Diabetes Telemedicine Study (KITES)
Randomised prospective single-center clinical trial evaluating the outcomes of children with type 1 diabetes followed up by remote telemedicine check-ups without their personal present at the outpatient clinic.
- Trial name
- KITES (NCT05484427)
- Testing
- Telemedicine
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- University Hospital, Motol
Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2)
MiniMed Fit Payload Wear Pediatric Study
The purpose of this study is to assess MiniMed Fit Payload adhesive components in different wear locations over a 7-day period to support development of the future commercialized patch pump in participants 7-17 years of age.
- Conditions
- Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2), Diabetes in Children, Diabetes in Adolescence
- Trial name
- NCT07675161
- Testing
- MiniMed Fit Payload adhesive components
- Where
- 5 sites in United States
- Volunteers
- 59 people
- Sponsor
- Medtronic MiniMed, Inc.
Vitamin D Deficiency, Dental Implant Failure Nos
Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure
In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D.
- Trial name
- NCT04906161
- Testing
- Vitamin D and calcium levels
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Obesity, Primary
A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm
Cross-over arm of the pilot study evaluating a treatment for obesity.
- Trial name
- NCT05939973
- Testing
- g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- USGI Medical
Fabry Disease
Treatment Protocol of Replagal for Patients With Fabry Disease
The study will evaluate the safety and efficacy of Replagal® (agalsidase alfa) at a dose of 0.2 mg/kg infused intravenously (IV) over 40 minutes, every other week.
- Trial name
- NCT01031173
- Testing
- agalsidase alfa
- Where
- 25 sites in United States
- Sponsor
- Shire
Low Birth Weight Baby, Metabolic Syndrome
Periodontitis and Adverse Pregnancy Outcomes in Metabolic Syndrome Patients- Interventional Study
Aim The Aim of the current study is to establish the association between periodontitis and adverse pregnancy outcomes in metabolic syndrome (Mets) patients and to evaluate the effect of intervention. Objectives 1.
- Conditions
- Low Birth Weight Baby, Metabolic Syndrome, Pregnancy Complications, Adverse Pregnancy Outcomes
- Trial name
- NCT03381469
- Testing
- Comprehensive periodontal treatment, single visit supragingival scaling
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 150 people
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Knee Osteoarthritis, Metabolic Disease
Bracing for Patellofemoral Osteoarthritis
BACKGROUND: Despite the prevalence of patellofemoral ostearthritis (OA), this joint has received relatively little attention in the OA literature and there are few treatment options for individuals with patellofemoral OA.
- Trial name
- NCT02984254
- Testing
- Womac, Lequesne, Timed-up-and-go (TUG)
- Volunteers
- 52 people
- Sponsor
- University of Sao Paulo General Hospital
Mucopolysaccharidosis II
Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome)
OBJECTIVES: I. Evaluate the safety and feasibility of treating mucopolysaccharidosis II (mild Hunter syndrome) by lymphocyte gene therapy. II.
- Trial name
- NCT00004454
- Testing
- lymphocyte gene therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Dialysis, Chronic Kidney Disease
Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease
The goal of this this randomized, clinical trial is to test an automated insulin delivery system (AID) in people with type 1 or type 2 diabetes who are on hemodialysis, peritoneal dialysis, or have advanced chronic kidney disease…
- Conditions
- Dialysis, Chronic Kidney Disease, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT06330194
- Testing
- 2nd Generation Automated Insulin Delivery (AID) system
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes, Diabetes Mellitus, Type 2
A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs)
This trial is conducted in Asia. The aim of this trial is to confirm the efficacy of insulin degludec/liraglutide in controlling glycaemia in Chinese subjects with type 2 diabetes mellitus inadequately controlled on oral…
- Trial name
- DUAL™ I China (NCT03172494)
- Testing
- Insulin degludec/liraglutide, Insulin degludec, Liraglutide
- Where
- 36 sites in China
- Volunteers
- 720 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in India
This study is conducted in Asia. The aim of this observational study is to evaluate the current status of diabetes management, control, and complications in diabetic subjects in India.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare India (NCT01351922)
- Testing
- No treatment given
- Where
- India
- Volunteers
- 12,000 people
- Sponsor
- Novo Nordisk A/S
Cardiovascular Diseases, Metabolic Diseases
Healthy Aging Longitudinal Study in Taiwan
The general aim of this study is to establish a longitudinal cohort of older persons in order to examine the physiological, environmental and genetic risk factors for physical disability, frailty, cardiovascular disease, and…
- Trial name
- HALST (NCT02677831)
- Volunteers
- 5,664 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Nutrition, Healthy, Weight Loss
Effect of a Postbiotic Supplementation in Overweight and Obese Subjects: A Randomized Controlled Trial (PARABIOTICS-2).
The principal objective of this project is to evaluate the effect of a postbiotic supplement (inactivated microorganism) on body composition and other physiological and metabolic parameters related to excess body weight in…
- Conditions
- Nutrition, Healthy, Weight Loss, Overweight and Obesity
- Trial name
- PARABIOTICS-2 (NCT07165431)
- Testing
- Postbiotic + nutritional recommendations
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
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