Clinical trials: Metabolomics
Mastitis
Global Effects of a Probiotic Strain on Lactating Women
In this study, the investigators will try to confirm if application of probiotic strains isolated from breast milk actually have a beneficial effect on women suffering lactational mastitis.
- Trial name
- PROBIOLAC (NCT01124448)
- Testing
- Lactobacillus salivarius PS2
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Primary Insomnia
Metabolomics of Insomnia-Related Hyperarousal
Individuals with insomnia have been shown to have higher overall metabolic rates compared to good sleepers, but it is not known which metabolic processes are involved.
- Trial name
- NCT01957111
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Schizophrenia
Metabolic Signatures and Biomarkers in Schizophrenia
We plan to use a metabolomics lipid platform to map biochemical signatures in unmedicated schizophrenic patients prior to and 4 weeks post treatment with the antipsychotic drug aripiprazole and compare that to lipid perturbations…
- Trial name
- NCT00466310
- Testing
- Aripiprazole, Risperidone, Healthy volunteers
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Exploratory Study of Circadian Relationships Between Social Behavior, Blood Pressure and Metabolomics
As citizens of the information age, humans leave digital traces of behavior in their communication and movement patterns through our cell phone.
- Trial name
- NCT02249793
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Plastic Bronchitis, Protein-Losing Enteropathies
Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis
Plastic bronchitis (PB) is a rare, most often pediatric disease characterized by the formation of obstructive airway casts primarily composed of fibrin.
- Conditions
- Plastic Bronchitis, Protein-Losing Enteropathies, Healthy
- Trial name
- PLATyPuS (NCT02315898)
- Testing
- Treatment-inhaled tPA
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Adiposity, Insulin Resistance
PREterM FOrmula Or Donor Breast Milk for Premature Babies
In order to address this crucial question, central to preterm newborn care, a multicentre United Kingdom (UK) -wide study randomising 4000 preterm babies would be necessary to achieve sufficient power to evaluate the impact on…
- Conditions
- Adiposity, Insulin Resistance, Metabolomic Profile, microRNA Profile
- Trial name
- PREMFOOD (NCT01686477)
- Testing
- Unfortified Human donor Milk used to make up any shortfall in mother's own milk, Fortified Human donor Milk used to make up any shortfall in mother's own milk, Preterm Formula used when there is a shortfall in mother's own milk
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Type 2 Diabetes, Obesity
Metabolomic Analysis of Hepatic Insulin Resistance
This is a pilot study to show that it is possible to identify the specific types of fats in blood, adipose tissue, and liver tissue.
- Trial name
- NCT01833403
- Testing
- Hyperinsulinemic-euglycemic clamp
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stability & Variability of Lipid-derived Molecules in Sweat
Investigating the Stability, Variability and Mechanism of Incorporation of Lipid Mediators Into Eccrine Sweat
The purpose of this study is to see what the differences are in sweat (amount and small molecule content) collected from different sites of the body and by different methods of sweat stimulation.
- Trial name
- NCT02935894
- Testing
- Ibuprofen, Physiological induction of sweating, Pilocarpine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Nutritional and Metabolic Diseases
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
The purpose of this study is to identify metabolic signatures associated with malodor conditions. The investigators will perform state-of-the art metabolomics tests and bioinformatic data mining to explore if conditions leading…
- Trial name
- NCT02683876
- Where
- 2 sites in United States, Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mebo Research, Inc.
Blood Pressure
Health Effects of Indoor Air Filtration in Healthy Chinese Adults
This study aims to detect serum metabolite changes, as well as other health indicators with the intervention of air purifiers on a randomized, crossover, double-blind trial.
- Trial name
- NCT02712333
- Testing
- Air Purifiers
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fudan University