Clinical trials: Metastasis to Liver
Ovarian Neoplasms, Colorectal Neoplasms
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy.
- Conditions
- Ovarian Neoplasms, Colorectal Neoplasms, Melanoma, Small Cell Lung Cancer
- Trial name
- NCT00132704
- Testing
- Ionizing radiation (IR) therapy, Ionizing radiation (IR)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neuroendocrine Tumors, Liver Metastases
TheraSphere Selective Internal Radiation Therapy (SIRT) as Treatment for Neuroendocrine Tumours With Liver Mets
This is an open label study for patients with inoperable metastatic neuroendocrine liver deposits to see whether treatment with Selective Internal Radiation Therapy (TheraSpheres) could lead to improved treatment response rates…
- Trial name
- ArTisaN (NCT04362436)
- Testing
- TheraSpheres Selective Internal Radiation Therapy (SIRT)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Imperial College London
Primary Liver Cancer, Secondary Liver Cancer
Preoperative Physical Activity Intervention in Patients Before Planned Liver Resection for Cancer (APACHE)
The aim of this study is to assess the impact of preoperative physical activity on physical capacities of patients undergoing liver resection for primary or secondary liver cancer.
- Conditions
- Primary Liver Cancer, Secondary Liver Cancer, Liver Metastases
- Trial name
- APACHE (NCT03518632)
- Testing
- Interval training, Standard Oncologic care
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Célia Turco
Liver Metastases, Colorectal Cancer
Dynamic ctDNA Detection for Colorectal Cancer Liver Metastases
Evaluating the value of dynamic monitoring of a colorectal cancer liver metastasis cohort underwent curative resection after receiving multipoint ctDNA detecting in predicting recurrence prognosis and guiding adjuvant…
- Conditions
- Liver Metastases, Colorectal Cancer, Surgery, Circulating Tumor DNA
- Trial name
- NCT06404593
- Testing
- Blood sampling
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Peking University Cancer Hospital & Institute
Colorectal Cancer, Metastatic Cancer
Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase II trial to study the effectiveness of vaccine therapy in treating patients who have colorectal cancer that has spread to the…
- Trial name
- NCT00033748
- Testing
- monoclonal antibody 11D10 anti-idiotype, monoclonal antibody 3H1 Alu Gel
- Where
- 75 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Melanoma, Uveal Neoplasms
The Scandinavian Randomized Controlled Trial of Isolated Hepatic Perfusion for Uveal Melanoma Liver Metastases
A randomized controlled, open-label, multi-centre study evaluating if Isolated Hepatic Perfusion (IHP) increases Overall Survival compared with Best Alternative Care (BAC) in patients with isolated liver metastases from uveal…
- Trial name
- SCANDIUM (NCT01785316)
- Testing
- IHP
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Vastra Gotaland Region
Metastatic Colorectal Cancer
Radiosensitizing Chemotherapy withSBRT for the Treatment of Inoperable Liver and/or Lung Metastases of CRC
The purpose of this study is to study stereotactic radiotherapy with a dose of 40 Gy in 4 fractions over 2 weeks with concomitant 40 mg/m2 of irinotecan (1st and 3rd irradiation session).
- Trial name
- RSCAMPTO (NCT01220063)
- Testing
- Radiation, Irinotecan
- Where
- 6 sites in France
- Volunteers
- 47 people
- Sponsor
- Institut Cancerologie de l'Ouest
Melanoma (Skin), Metastatic Cancer
Interleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Stage IV Melanoma Metastatic to the Liver
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill tumor cells. Histamine dihydrochloride may help interleukin-2 kill more tumor cells by making tumor cells more sensitive to the drug.
- Trial name
- NCT00039234
- Testing
- aldesleukin, histamine dihydrochloride
- Where
- 19 sites in United States, Canada and 2 more
- Sponsor
- Maxim Pharmaceuticals
Liver Cancer, Liver Metastases
Real-time Imaging of Holmium Radioembolization: a Feasibility Study
This is a feasibility study in which patients with liver tumors are treated with holmium radioembolization under real time MR imaging.
- Trial name
- Emeritus (NCT04269499)
- Testing
- QuiremSpheres®
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Radboud University Medical Center
Patients With Liver Metastases From Colorectal Cancer
Modelling Internal Hepatic Movement With an External Abdominal Marker
This study tests the feasibility and reproducibility of patient-specific motion models. These will be used for quantification of safe margin reduction.
- Trial name
- NCT00299299
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Melanoma, Ocular, Melanoma, Cutaneous
Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)
The primary purpose of this study is to determine the feasibility of liver stereotactic body radiation therapy (SBRT) given in combination with systemic therapy (ipilimumab and nivolumab) in adults with metastatic melanoma with…
- Conditions
- Melanoma, Ocular, Melanoma, Cutaneous, Metastatic Melanoma, Melanoma, Mucosal
- Trial name
- NCT05169957
- Testing
- Ipilimumab, Nivolumab, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan Rogel Cancer Center
Pancreatic Cancer
Nimotuzumab Plus AG in Pancreatic Cancer With Liver Metastasis
This is a prospective, open-label, single arm clinical study. The main purpose of the study is to evaluate the clinical efficacy and safety of Nimotuzumab combined with AG in the treatment of pancreatic cancer with liver…
- Trial name
- NCT06405685
- Testing
- Nimotuzumab, AG
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Colon Cancer Liver Metastasis
Safety of TACE With Oxaliplatin, Irinotecan and Raltitrexed for Refractory Colorectal Cancer Liver Metastasis
The purpose of this study is to observe whether hepatic infusion by oxaliplatin, irinotecan and raltitrexed with or without embolization by lipiodol or microspheres are effective in the treatment of refratory liver metastasis…
- Trial name
- NCT02631564
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Colon Carcinoma, Rectum Carcinoma
L-BLP25 in Patients With Colorectal Carcinoma After Curative Resection of Hepatic Metastases
Comparative evaluation of recurrence-free survival (RFS) time and 3 year overall survival (OS) time between the treatment groups (L-BLP25 plus cyclophosphamide versus placebo and saline infusion).
- Trial name
- LICC (NCT01462513)
- Testing
- L-BLP25
- Where
- 21 sites in Austria, Germany
- Volunteers
- 122 people
- Sponsor
- Prof. Dr. Carl Schimanski
Colorectal Cancer, Liver Metastases
Metastatic Colorectal Cancer Liver Metastases Outcomes After Resin 90Y Microsphere Radioembolization in the USA Evaluation Project
Investigator initiated multi-institutional retrospective review of clinical and radiographic outcomes after 90Y resin microsphere radioembolization for metastatic colorectal liver metastases in the USA.
- Trial name
- MORE (NCT01815879)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Andrew Kennedy
Liver Metastases, Mucinous Adenocarcinoma of the Colon
Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surgery
This phase 0 trial is studying whether 2 weeks of cetuximab and dasatinib will change tumor cells in patients with colorectal cancer and liver metastases that can be removed by surgery.
- Conditions
- Liver Metastases, Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum, Recurrent Colon Cancer
- Trial name
- NCT00835679
- Testing
- cetuximab, dasatinib, therapeutic conventional surgery
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- National Cancer Institute (NCI)
Liver Metastases, Tumor
End Hole vs. Pressure-Modulated Delivery of Y-90 Resin Microspheres to Liver Metastases.
Patients with liver metastases undergoing planning arteriography for Y-90 administration by interventional radiology will be screened for study enrollment.
- Trial name
- NCT07791446
- Testing
- The TriNav Infusion Systems, Standard End Hole Microcatheter
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Stanford University
Colorectal Cancer, Metastatic Cancer
Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver
RATIONALE: Radiofrequency ablation may be able to shrink or destroy cancer cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00004142
- Testing
- Floxuridine, Fluorouracil (5-FU), Conventional surgery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Liver Metastases, Hepatocellular Carcinoma
Alternative Surgical Policy for Central Liver Tumors
Major hepatectomies have not negligible morbidity and mortality. However, when tumors invade middle hepatic vein (MHV) at caval confluence major surgery is usually recommended.
- Trial name
- NCT00600522
- Testing
- Ultrasound-guided hepatectomy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Milan
Liver Metastases, Hepatocarcinoma
Use of DwI-MR to Predict Chemotherapy Response of Liver Metastases and Hepatocarcinoma
One of the most recent and interesting field of diagnostic imaging is diffusion-weighted MR imaging (DW-MRI). Various studies evaluated the application of DW-MRI to diffuse liver disease and focal liver lesions providing…
- Trial name
- NCT01411579
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Stefano Colagrande
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.