Clinical trials: Methamphetamine
Amphetamine-Related Disorders
Tyrosine for Methamphetamine Dependence - 1
The purpose of this study is to evaluate efficacy of tyrosine as a treatment for methamphetamine dependence in an outpatient treatment setting providing group psychosocial interventions.
- Trial name
- NCT00000322
- Testing
- Tyrosine
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Use Disorder, Pregnancy
Transcranial Magnetic Stimulation for Methamphetamine Use Disorder During Pregnancy
The goal of this clinical trial is to learn whether transcranial magnetic stimulation, also called TMS, is a practical and acceptable treatment option for methamphetamine use disorder during pregnancy.
- Trial name
- NCT07849530
- Testing
- 4- Week Dual-Target Transcranial Magnetic Stimulation (TMS), Accelerated Dual-Target Transcranial Magnetic Stimulation (aTMS), Treatment as Usual (TAU)
- Volunteers
- 45 people
- Sponsor
- University of Utah
Methamphetamine Dependence
Safety and Efficacy Study of Vigabatrin to Treat Methamphetamine Dependence
The objective of this study is to demonstrate that a larger proportion of vigabatrin-treated subjects than placebo-treated subjects will be methamphetamine-free in the last 2 weeks of the study's Treatment Phase (Weeks 11 and 12).
- Trial name
- NCT00730522
- Testing
- CPP-109 vigabatrin
- Where
- 8 sites in United States
- Volunteers
- 55 people
- Sponsor
- Catalyst Pharmaceuticals, Inc.
Methamphetamine Dependence, Substance Abuse
Varenicline for Methamphetamine Dependence
Methamphetamine (MA) dependence is a source of continuing danger for both individuals and society. While there are some behavioral treatments, they are not always effective.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT01365819
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence, Substance Abuse
Varenicline-Methamphetamine Interaction Study (2008)
The primary aim of the study is to determine the safety and tolerability of treatment with Varenicline in methamphetamine-dependent volunteers.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT00733967
- Testing
- Varenicline
- Sponsor
- Baylor College of Medicine
Opioid Use Disorder, Medication Adherence
MHealth Incentivized Adherence Plus Patient Navigation
Polysubstance use involving opioids and methamphetamine is emerging as a new public health crisis. Patients with opioids and methamphetamine use often experience serious medical complications requiring hospitalization, which…
- Conditions
- Opioid Use Disorder, Medication Adherence, Polysubstance Drug Use (Indiscriminate Drug Use), Methamphetamine-dependence
- Trial name
- MIAPP (NCT06027814)
- Testing
- Patient Navigation and mHealth (PN+mHealth)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Amphetamine Dependence
Trial of Modafinil for Methamphetamine Dependence
The study aims to evaluate the safety and efficacy of modafinil (200 mg/day) over 10 weeks plus a tailored cognitive behavioural therapy program in the treatment of methamphetamine dependence.
- Trial name
- NCT00123370
- Testing
- Modafinil
- Where
- 2 sites in Australia
- Volunteers
- 87 people
- Sponsor
- The University of New South Wales
Amphetamine-Related Disorders, Cocaine-Related Disorders
Computerized Exercise to Alter Stimulant Approach Responses
The purpose of this study is to evaluate the Computerized Exercise to Alter Stimulant Approach Responses (CEASAR), a novel stimulant use cessation intervention, for clients currently enrolled in a treatment centre for mental…
- Conditions
- Amphetamine-Related Disorders, Cocaine-Related Disorders, Substance-Related Disorders
- Trial name
- CEASAR (NCT03902405)
- Testing
- Active CEASAR Intervention
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
HIV Medication Adherence, Methamphetamine Use
Intervention Targeting Medication Adherence and Methamphetamine Use in HIV Positive Men (ACE)
The primary aim is to test an innovative 8-session intervention, based on Motivational Interviewing and Cognitive Behavioral Skills-Training for the co-occurrence of methamphetamine use and highly active antiretroviral therapy…
- Conditions
- HIV Medication Adherence, Methamphetamine Use, Sexual Risk, Poly-substance Use
- Trial name
- ACE (NCT01122186)
- Testing
- Motivational Interviewing + Cognitive Behavioral Skills Training, Education Attention Control
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Hunter College of City University of New York
ADHD, Attention Deficit Hyperactivity Disorder
A Study of Combination Therapy in Children With ADHD
Lack of appetite and weight loss are a common side effect of ADHD therapy with amphetamines such as methylphenidate. Lack of sufficient food intake has been shown to have negative effects on weight and height as well as learning…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood
- Trial name
- NCT01940978
- Testing
- Methylphenidate ER, Cyproheptadine
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Douglas Sears
Methamphetamine-dependence
Monthly Injectable BUP for MA Use Disorder (MURB) Trial
This study is a 12-week randomized, double-blind, placebo-controlled trial that will investigate the use of injectable buprenorphine (BUP-Inj) compared to injectable placebo (PBO-Inj) for the treatment of methamphetamine use…
- Trial name
- CTN-0110 (NCT05283304)
- Testing
- Buprenorphine injection (BUP-Inj)
- Where
- 6 sites in United States
- Volunteers
- 18 people
- Sponsor
- Madhukar H. Trivedi, MD
HIV, Drug Addiction
Treating South African Pregnant Women for Methamphetamine
The purpose of this study was to develop and initially evaluate an efficacious, comprehensive, culturally sensitive, women-centered model of care for pregnant South African women by adapting and refining PI Jones'…
- Trial name
- NCT01386138
- Testing
- Psycho-education, Experimental
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- RTI International
Substance-Related Disorders
DOX as a Potential Treatment for Methamphetamine Dependence
The purpose of the study is to asses the potential interactions between methamphetamine and doxazosin in methamphetamine-dependent volunteers who are not seeking treatment.
- Trial name
- DOX-Meth (NCT02785393)
- Testing
- Sugar Pill, Doxazosin
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Amphetamine-Related Disorders
Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM (M2.0)
The investigators recently conducted a double-blind, randomized controlled trial (n=60) of limited duration (12 weeks), and found that compared with placebo, oral mirtazapine, an FDA-approved antidepressant, significantly reduced…
- Trial name
- NCT01888835
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Phillip Coffin, MD, MIA
Methamphetamine Use Disorder
Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV
The goal of this clinical trial is to learn whether it is possible to use intramuscular (IM) ketamine in combination with psychotherapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in publicly insured patients…
- Trial name
- KARE (NCT06538285)
- Testing
- Ketamine, Psychotherapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Nicky Mehtani, MD, MPH
Amphetamine Use Disorders
Closed-loop cTBS for the Core Clinical Features of Methamphetamine Use Disorder
Using specific EEG biomarkers in methamphetamine-dependent individuals, this study systematically probes closed-loop continuous Theta-burst Stimulation (cTBS) based on brain states, assessing dosage, neurologic and behavioral…
- Trial name
- NCT06457243
- Testing
- Closed-loop cTBS stimulation based on addiction induced states
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Methamphetamine-dependence, Methamphetamine Abuse
Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200
This Phase 2 study will evaluate the safety and efficacy of monthly intravenous doses of IXT-m200 in treatment-seeking individuals with methamphetamine (METH) use disorder.
- Trial name
- OUTLAST (NCT05034874)
- Testing
- IXT-m200
- Where
- 9 sites in United States
- Volunteers
- 61 people
- Sponsor
- InterveXion Therapeutics, LLC
Substance Use Disorders, Opioid Use Disorder
Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR) device in substance use disorder (SUD)…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder
- Trial name
- EDITOR (NCT06434818)
- Testing
- EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Evon Medics LLC
HIV/AIDS, Methamphetamine Abuse
Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use
This study is a single-arm, non-randomized pilot study. Eligible participants are newly enrolled participants in an outpatient methamphetamine treatment program, and study activities will take place contemporaneously with…
- Conditions
- HIV/AIDS, Methamphetamine Abuse, Depression
- Trial name
- NCT03864653
- Testing
- MoodGym
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Friends Research Institute, Inc.
Methamphetamine Induced Psychosis
Psychiatric Symptom Predictors in Methamphetamine-Induced Psychosis
This longitudinal observational study aimed to investigate environmental, familial, and individual factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder…
- Trial name
- NCT07459257
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital