Clinical trials: Methamphetamine Abuse
Methamphetamine-dependence, Methamphetamine Abuse
Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200
This Phase 2 study will evaluate the safety and efficacy of monthly intravenous doses of IXT-m200 in treatment-seeking individuals with methamphetamine (METH) use disorder.
- Trial name
- OUTLAST (NCT05034874)
- Testing
- IXT-m200
- Where
- 9 sites in United States
- Volunteers
- 61 people
- Sponsor
- InterveXion Therapeutics, LLC
Cognitive Dysfunction, Stimulant Use
Change in Cognitive Function in Stimulant Users
In Hong Kong, methamphetamine use is common and cocaine use has increased steadily over the past few years. While the use of ketamine decreased from 35.8% in 2015 to 13.9% in 2017, methamphetamine and cocaine have become the most…
- Conditions
- Cognitive Dysfunction, Stimulant Use, Methamphetamine Abuse, Cocaine Use
- Trial name
- SToP-S_CogFx (NCT04061941)
- Testing
- Cognitive Assessment
- Where
- Hong Kong
- Volunteers
- 93 people
- Sponsor
- The University of Hong Kong
Dopamine D2/3 Receptor Availability, Cognitive Function
Dopamine D2/D3 Receptor Upregulation by Varenicline in Methamphetamine Users
While deficits in dopamine D2-type receptor availability have been linked to substance use disorders, higher availability associates with better behavioral treatment outcomes for stimulant dependence and resilience to addiction.
- Conditions
- Dopamine D2/3 Receptor Availability, Cognitive Function, Methamphetamine Abuse
- Trial name
- NCT03059563
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Abuse
Exercise in Methamphetamine Use Disorder Upregulation and Neural Function
The purpose of this research study is to determine the effects of an exercise intervention and health-education program on brain dopamine receptors and on cognitive functions that have been linked to these receptors.
- Trial name
- NCT03709667
- Testing
- EX, CON
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Abuse
Theta Burst TMS for Treatment of Methamphetamine Use Disorder
This study is using Transcranial Magnetic Stimulation (TMS) to determine if interventional psychiatry treatment can help with the treatment of Methamphetamine Use Disorder.
- Trial name
- NCT06372288
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Carilion Clinic
Methamphetamine, Methamphetamine Abuse
Delivering Contingency Management in Outpatient Addiction Treatment
Methamphetamine misuse has become a growing concern in Alberta, creating a burden on the health care system. Further, individuals who use methamphetamine in Alberta exhibit significant difficulty remaining in treatment.
- Conditions
- Methamphetamine, Methamphetamine Abuse, Methamphetamine-dependence, Contingency Management
- Trial name
- PRISE (NCT04544124)
- Testing
- Contingency management
- Where
- 2 sites in Canada
- Volunteers
- 88 people
- Sponsor
- University of Calgary
Methamphetamine Abuse, Methamphetamine-dependence
ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals
This study aims to assess the feasibility, acceptability and preliminary effectiveness of Acceptance Commitment Therapy, in conjunction with motivation enhancement, and the use of the ChillTime App, in reducing methamphetamine…
- Trial name
- NCT05334914
- Testing
- Acceptance Commitment Therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
HIV Infections, Methamphetamine-dependence
Stimulant Use and Methylation in HIV
This study will leverage extracted leukocyte DNA specimens from a completed NIH-funded project to examine the efficacy of a behavioral intervention model that reduced stimulant use on DNA methylation over 6 months.
- Conditions
- HIV Infections, Methamphetamine-dependence, Methamphetamine Abuse
- Trial name
- NCT05916989
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Florida International University
Methamphetamine Abuse
Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder
The efficacy of cognitive behavioral therapy(CBT) in treatment of methamphetamine use disorder
- Trial name
- NCT05593796
- Testing
- cognitive behavioral therapy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Methamphetamine Abuse
Skin Disease in Methamphetamine Abuse
1. To detect the skin diseases in patients using methamphetamine
- Trial name
- NCT05971043
- Volunteers
- 500 people
- Sponsor
- Assiut University
Methamphetamine-dependence, Substance Abuse
Safety Interaction Trial Ibudilast and Methamphetamine
This study is designed to collect data to determine whether a medication, ibudilast, is safe for use as a potential treatment for methamphetamine-dependent people.
- Trial name
- NCT01217970
- Testing
- Ibudilast 20mg, Ibudilast 50mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Abuse
Demonstration of a Digital Care Program for Methamphetamine Use Disorder
This Phase I Small Business Innovation Research (SBIR) project will examine the technical merit and real-world feasibility of the Affect smartphone application ("app") as the core component of the Affect digital care program for…
- Trial name
- NCT05206175
- Testing
- Affect Treatment Program for Methamphetamine Use Disorder
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Affect Therapeutics, Inc.
Methamphetamine Abuse
Digital Therapeutics Smartphone Application for Methamphetamine Use Disorder
One hundred participants were recruited and randomized into a digital therapeutics (DTx) group (n=52) and a treatment as usual (TAU) group (n=48).
- Trial name
- NCT05550493
- Testing
- Cognitive Behavioral Therapy, Counseling, Approach Bias Modification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Burns, Acute Lung Injury
Amphetamine Induced Adult Respiratory Distress Syndrome
Methamphetamine and amphetamine has various cardiovascular and central nervous system effects. Long-term use is associated with many adverse health effects including cardiomyopathy, hemorrhagic, and ischemic stroke.
- Conditions
- Burns, Acute Lung Injury, Acute Respiratory Distress Syndrome, Methamphetamine Abuse
- Trial name
- NCT05611385
- Testing
- Difference in development of Acute Lung Injury in Amphetamine positive and negative patients
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Arrowhead Regional Medical Center
Methamphetamine Abuse, HIV/AIDS
FASTLANE II: Reducing Sex, Drug, and Mental Health Risk
The study uses a repeated measures, single group pretest-posttest design methodology to examine the feasibility, acceptability, and preliminary effectiveness of the FASTLANE II intervention aimed at decreasing risky sex behaviors…
- Conditions
- Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
- Trial name
- FLII (NCT04109014)
- Testing
- FASTLANE II
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Methamphetamine Dependence, Methamphetamine Abuse
An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence
The primary objective is to determine the dose dependent effects of treatment with perindopril on methamphetamine (MA)-induced craving and on the reinforcing effects of MA indexed by MA self-administration.
- Conditions
- Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
- Trial name
- NCT01062451
- Testing
- Perindopril, Candesartan
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Methamphetamine-dependence, Methamphetamine Abuse
Study of Antibody for Methamphetamine Outpatient Therapy
This study evaluates the ability of IXT-m200 to change methamphetamine concentrations in blood and alter the way methamphetamine feels.
- Trial name
- STAMPOUT (NCT03336866)
- Testing
- IXT-m200
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- InterveXion Therapeutics, LLC
Methamphetamine Abuse
Field Study of a Digital Therapeutic Platform to Facilitate Treatment for Methamphetamine-Primary Stimulant Use Disorder
The overall purpose of the observational, investigational pilot study is to assess the clinical utility of the Affect digital health platform (the Affect® "app") as part of the Affect program of treatment for…
- Trial name
- NCT05266716
- Testing
- Affect Methamphetamine Treatment Program
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Affect Therapeutics, Inc.
Methamphetamine Abuse
A Pilot Study of Repetitive Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorders
We propose a single-arm clinical trial, with historical controls as a comparison group for select outcomes. Subjects with MAUD will receive 16 sessions of dual-target theta burst stimulation to the DLPFC and MPFC over 4 weeks.
- Trial name
- NCT04883021
- Testing
- Dual Target Theta Burst Stimulation
- Where
- United States
- Sponsor
- University of New Mexico
Methamphetamine Abuse, Pulmonary Hypertension
Screening of Pulmonary Hypertension in Methamphetamine Abusers
Methamphetamine is misuse if classified as a "likely" risk factor for pulmonary arterial hypertension (PAH). Nevertheless the actual prevalence of and a screening strategy for PAH in methamphetamine users have not been…
- Trial name
- SOPHMA (NCT04019600)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong