Clinical trials: Methamphetamine Addiction
Methamphetamine Dependence, Substance Abuse
Varenicline for Methamphetamine Dependence
Methamphetamine (MA) dependence is a source of continuing danger for both individuals and society. While there are some behavioral treatments, they are not always effective.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT01365819
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
Safety and Efficacy Study of Vigabatrin to Treat Methamphetamine Dependence
The objective of this study is to demonstrate that a larger proportion of vigabatrin-treated subjects than placebo-treated subjects will be methamphetamine-free in the last 2 weeks of the study's Treatment Phase (Weeks 11 and 12).
- Trial name
- NCT00730522
- Testing
- CPP-109 vigabatrin
- Where
- 8 sites in United States
- Volunteers
- 55 people
- Sponsor
- Catalyst Pharmaceuticals, Inc.
Depression, Dual Diagnosis
A Randomized Double-Blind Controlled Trial of Creatine in Female Methamphetamine Users
Methamphetamine (MA) addiction is a public health concern that causes substantial harm to individual users, and imposes an economic burden in the U.S. totaling up to $48.3 billion annually.
- Conditions
- Depression, Dual Diagnosis, Drug Addiction
- Trial name
- NCT02192931
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Perry Renshaw
Methamphetamine Dependence
A Comparison of Paliperidone and Risperidone for Treatment of Patirnts With Methamphetamine-Associated Psychosis
Methamphetamine-associated psychosis (MAP) has been considered a pharmacological or environmental pathogen model of schizophrenia (SCZ) due in part to similarities in clinical presentation (i.e.
- Trial name
- NCT01822730
- Testing
- paliperidone, Risperidone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wei Hao
HIV-1-infection, Methamphetamine-dependence
Effect of Methamphetamine on Residual Latent HIV Disease Study
The most commonly used illicit stimulant in HIV-infected individuals is methamphetamine (MA). Prior studies demonstrate strong evidence that MA promotes increased HIV transcription as well as immune dysregulation.
- Trial name
- EMRLHD (NCT03825536)
- Testing
- Oral Methamphetamine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Amphetamine-Related Disorders
A Cognitive Behavioral Therapy-Based Text Message Intervention for Methamphetamine Dependence
This Phase I behavior therapy development study seeks to improve treatment outcomes for methamphetamine (MA)-dependent subjects by developing a novel cognitive behavioral therapy- (CBT-) based short message service (SMS) text…
- Trial name
- NCT01899313
- Testing
- CBT- based SMS text messaging intervention, CBT group therapy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- California Pacific Medical Center Research Institute
Methamphetamine Addiction
A Pilot Trial of Modafinil for Treatment of Methamphetamine Dependence
Patients treated for methamphetamine dependence have high rates of relapse, and no pharmacotherapy has yet been demonstrated to be efficacious.
- Trial name
- NCT00538655
- Testing
- modafinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- California Pacific Medical Center Research Institute
Methamphetamine-dependence
Transcranial Magnetic Stimulation for Treatment of Methamphetamine Dependence
Repetitive transcranial magnetic stimulation (rTMS) was used to treat methamphetamine (MA) addiction in previous studies, while the evidence-based protocols still required.
- Trial name
- NCT03827785
- Testing
- rTMS treatment group
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Amphetamine-Related Disorders
Bupropion for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess the efficacy and safety of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence
- Trial name
- NCT00069251
- Testing
- Bupropion
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Dependence
Study of Naltrexone for Methamphetamine Addiction
The purpose of this study is to determine whether methamphetamine-dependent individuals will use less methamphetamine when treated with naltrexone.
- Trial name
- NCT00984360
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- California Pacific Medical Center Research Institute
Methamphetamine Abuse, Methamphetamine Dependence
Safety Assessment of Atomoxetine With MA IV Administration
This is a study of 4 nontreatment seeking individuals who were MA-dependent and the safety and tolerability of atomoxetine. This double-blind, placebo-controlled, within-subjects study is to determine the safety and tolerability…
- Trial name
- NCT01019707
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Methamphetamine
Effectiveness of Bupropion Combined With Behavioral Therapy for Treating Methamphetamine Dependence - 2
Methamphetamine is an addictive stimulant drug that strongly activates certain parts of the brain. The purpose of this study is to determine the effectiveness of bupropion in combination with behavioral therapy for the treatment…
- Trial name
- NCT00135785
- Testing
- Bupropion
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM (M2.0)
The investigators recently conducted a double-blind, randomized controlled trial (n=60) of limited duration (12 weeks), and found that compared with placebo, oral mirtazapine, an FDA-approved antidepressant, significantly reduced…
- Trial name
- NCT01888835
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Phillip Coffin, MD, MIA
Methamphetamine Dependence
Modafinil vs Placebo for the Treatment of Methamphetamine Dependence
Modafinil is a non-amphetamine type stimulant that acts as a wakefulness-promoting drug, and is approved for managing symptoms of narcolepsy (i.e., daytime somnolence).
- Trial name
- Modafinil (NCT00469508)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
A Randomized, Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence
The proposed study will establish the safety and efficacy of modafinil in the treatment of methamphetamine dependence, as well as assess the affects of modafinil on cognitive function in methamphetamine users and on…
- Trial name
- NCT01354470
- Testing
- Modafinil
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- California Pacific Medical Center Research Institute
Methamphetamine Dependence
Clinical Efficacy of Atomoxetine for Methamphetamine Dependence
The purpose of this study is to examine the ability of atomoxetine compared to placebo to increase time to relapse in methamphetamine dependent volunteers.
- Trial name
- ATM (NCT01557569)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas