Clinical trials: Methamphetamine Disorders
HIV Infections
Reduction of Drug Use and HIV Risk Among Out-of-Treatment Methamphetamine Users
There is a need to identify and test effective strategies to reduce meth use and human immunodeficiency virus (HIV) risk behaviors in heterosexuals.
- Trial name
- NCT01161485
- Testing
- HIV Testing and Counseling, Contingency Management, Strengths-based case management
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Substance Abuse, HIV Infections
Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV Behaviors
Studies demonstrate that methamphetamine (meth) use is associated with high-risk sexual behavior among MSM, putting meth-using MSM at extraordinarily high risk for transmitting or acquiring HIV.
- Trial name
- NCT00497081
- Testing
- mirtazapine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
Methamphetamine Use Disorder
Bupropion in the Treatment of Methamphetamine Dependence
Methamphetamine dependence is a significant drug use disorder in the Midwest. While a number of psychosocial and pharmacological treatments have been studied, no specific treatments for methamphetamine have been identified.
- Trial name
- NCT00572234
- Testing
- bupropion SR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Methamphetamine-dependence, Methamphetamine Abuse
Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200
This Phase 2 study will evaluate the safety and efficacy of monthly intravenous doses of IXT-m200 in treatment-seeking individuals with methamphetamine (METH) use disorder.
- Trial name
- OUTLAST (NCT05034874)
- Testing
- IXT-m200
- Where
- 9 sites in United States
- Volunteers
- 61 people
- Sponsor
- InterveXion Therapeutics, LLC
Methamphetamine Use Disorder
Accelerated Development of Additive Pharmacotherapy Treatment for Methamphetamine Use Disorder
The aim of this 2-stage, 3-site study is to investigate the effectiveness and safety of a combination of extended-release depot naltrexone plus extended-release bupropion as a potential pharmacotherapy for methamphetamine (MA)…
- Trial name
- ADAPT (NCT01982643)
- Testing
- naltrexone plus bupropion
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Walter Ling
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Methamphetamine Induced Psychosis, Cannabis Use
Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use
This prospective cohort study aims to investigate factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP) with and without lifetime cannabis use (LCU).
- Trial name
- NCT07459270
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Amphetamine-Related Disorders
Tyrosine for Methamphetamine Dependence - 1
The purpose of this study is to evaluate efficacy of tyrosine as a treatment for methamphetamine dependence in an outpatient treatment setting providing group psychosocial interventions.
- Trial name
- NCT00000322
- Testing
- Tyrosine
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine Addiction
Robot-Assisted Intelligent Rehabilitation Treatment for Methamphetamine Use Disorders.
The purpose of this research is to evaluate the efficacy and safety of Robot-assisted rehabilitation intelligent system as a virtual stand-alone treatment, delivered with minimal clinical monitoring compared with treatment as…
- Trial name
- NCT04531384
- Testing
- robot-assisted rehabilitation intelligent treatment, standard psychotherapy treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Use Disorder
A Study for the Risky Decision-making Deficits Among Methamphetamine Dependence Individuals and Treatment
The risky decision-making deficits is the core feature of the methamphetamine (MA) dependence. Our previous research found that MA dependents have network abnormalities such as decision-making and rewarding.
- Trial name
- NCT06279273
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Addiction, Substance
Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History
A randomized controlled trial will be conducted to investigate whether a proposed algorithm that adjusts the congruency ratio based on the user's performance and difficulty can enhance the effectiveness of approach bias…
- Trial name
- NCT05794438
- Testing
- Static Approach Bias Modification, Adaptive Approach Bias Modification
- Where
- 12 sites in China
- Volunteers
- 139 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Methamphetamine Abuse, Methamphetamine Dependence
NAC as a Potential Treatment for Methamphetamine Dependence
The purpose of this study is to determine the effects of treatment with NAC, compared to treatment with placebo, on cue- and methamphetamine (MA)-induced craving and MA subjective effects in non-treatment-seeking MA-dependent…
- Conditions
- Methamphetamine Abuse, Methamphetamine Dependence, Substance Abuse
- Trial name
- NCT01063205
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Methamphetamine Dependence
Clinical Efficacy of Atomoxetine for Methamphetamine Dependence
The purpose of this study is to examine the ability of atomoxetine compared to placebo to increase time to relapse in methamphetamine dependent volunteers.
- Trial name
- ATM (NCT01557569)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas
Depression, Dual Diagnosis
A Randomized Double-Blind Controlled Trial of Creatine in Female Methamphetamine Users
Methamphetamine (MA) addiction is a public health concern that causes substantial harm to individual users, and imposes an economic burden in the U.S. totaling up to $48.3 billion annually.
- Conditions
- Depression, Dual Diagnosis, Drug Addiction
- Trial name
- NCT02192931
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Perry Renshaw
Drug Abuse, Drug Dependence
Prometa Pharmacotherapy for Methamphetamine Dependence
The purpose of this study is to assess the efficacy of the PROMETA pharmacotherapy compared to placebo for initiating abstinence and for preventing relapse to methamphetamine use in treatment-seeking individuals meeting criteria…
- Trial name
- NCT00260481
- Testing
- Prometa
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Stimulant Abuse, HIV Prevention
Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse
This study seeks primarily to test, in a two-arm randomized controlled trial (RCT), the efficacy of Project IMPACT, an intervention that integrates Behavioral Activation (BA) with HIV risk reduction (RR) counseling for…
- Conditions
- Stimulant Abuse, HIV Prevention, Substance Abuse
- Trial name
- NCT03175159
- Testing
- IMPACT, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Substance-Related Disorders, HIV Infections
STD Risk Reduction for Heterosexual Methamphetamine Users
This study will evaluate the effectiveness of a sexual risk reduction intervention in reducing sexual risk behavior in HIV uninfected, heterosexual people who use methamphetamine.
- Conditions
- Substance-Related Disorders, HIV Infections, Sexually Transmitted Diseases
- Trial name
- NCT00344214
- Testing
- Tri-focal cognitive behavioral therapy - social skills training (CBTSS) counseling program, Standard care
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- University of California, San Diego
HIV Infections, STDs
Promoting Safer Sex in HIV+ Homosexual and Bisexual Men Who Use Methamphetamine
This project studies the effectiveness of a sexual risk reduction intervention among HIV+ Men who have Sex with Men (MSM) and who use methamphetamine.
- Conditions
- HIV Infections, STDs, Methamphetamine Abuse
- Trial name
- NCT00291512
- Testing
- Theory-based counseling program
- Where
- United States
- Sponsor
- University of California, San Diego
Substance-Related Disorders, HIV
Expression of Stress Markers During Meth Treatment (EXPRESS+)
This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive…
- Trial name
- EXPRESS+ (NCT05558345)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Amphetamine-Related Disorders
Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1
The purpose of this study is to assess potential interactions between intravenous (IV) methamphetamine and oral bupropion.
- Trial name
- NCT00040040
- Testing
- Bupropion
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- National Institute on Drug Abuse (NIDA)