Clinical trials: Methylphenidate
Attention Deficit Hyperactivity Disorder
Methylphenidate and the Relations Between Emotional Processing and Social Functioning Among Children With ADHD
Children with ADHD are in high risk to develope social difficulties. The present study will examine the emotional processing in those children.
- Trial name
- NCT01278667
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Bnai Zion Medical Center
Attention-Deficit/ Hyperactivity Disorder (ADHD)
Pharmacogenomics of Stimulant Treatment Response
The "Pharmacogenomics of Stimulant Treatment Response" (PGx-STaR) study aims to identify genetic profiles related to methylphenidate treatment outcomes in children and adolescents aged 6-24 with Attention deficit/hyperactivity…
- Trial name
- PGx-STaR (NCT06221358)
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University of Calgary
Attention Deficit Hyperactivity Disorder
Methylphenidate Study in Young Children With Developmental Disorders
The purpose of this study is to determine if methylphenidate (a common brand name is Ritalin), a medicine used for treating older children with Attention Deficit and Hyperactivity Disorder (ADHD), is also safe and helpful for…
- Trial name
- NCT00517504
- Testing
- Methylphenidate
- Volunteers
- 48 people
- Sponsor
- University of Arizona
Attention Deficit/Hyperactivity Disorder
International Study to Predict Optimised Treatment in Attention Deficit/Hyperactivity Disorder
The aim of the iSPOT-A study is to: 1. identify brain, genetic and cognitive markers of Attention Deficit/Hyperactivity Disorder, and 2.
- Trial name
- NCT00863499
- Testing
- Short Acting Methylphenidate, Long Acting Methylphenidate
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 1,344 people, healthy volunteers welcome
- Sponsor
- BRC Operations Pty. Ltd.
ADHD
Omega-3 Fatty Acids Supplementation in ADHD
The overarching aim of the proposed study is to assess whether omega-3 fatty acids supplementation can augment the effects of methylphenidate in children with ADHD.
- Trial name
- NCT01777048
- Testing
- Omega-3 Fatty Acids Supplementation
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Methylphenidate, Metabolomics
Metabolic Mechanisms of the Electrophysiological Biomarkers for Response to Methylphenidate Treatment in Children With ADHD
To explore the relationship of treatment-related changes in electrophysiology and those in metabolomics for identification of the underlying metabolic mechanisms for the electrophysiological effects of methylphenidate in children…
- Trial name
- NCT06073470
- Testing
- methylphenidate
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Attention-Deficit/Hyperactivity Disorder
Real-World Evidence of Duration of Effect of Adhansia XR (Extended-Release) for Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to investigate the treatment effectiveness of Adhansia XR at month-2 after initiation, and the effectiveness of Adhansia XR overall and when compared with the active comparator group (Concerta) over…
- Trial name
- RE-DAX (NCT04507204)
- Testing
- Adhansia XR, Concerta
- Where
- 35 sites in United States
- Volunteers
- 267 people
- Sponsor
- Purdue Pharma LP
Attention Deficit Disorder With Hyperactivity, Autistic Disorder
Methylphenidate in Children and Adolescents With Pervasive Developmental Disorders
This study will evaluate the efficacy and safety of methylphenidate for treating hyperactivity, impulsiveness, and distractibility in 60 children and adolescents with Pervasive Developmental Disorders (PDD).
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Disorder, Pervasive Development Disorders
- Trial name
- NCT00025779
- Testing
- methylphenidate, guanfacine
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Obesity
The Effects of Methylphenidate on Energy Intake and Energy Expenditure
The Problem: Obesity is one of the leading causes of chronic disease and death. The efficacy of diet and exercise to sustain weight loss over the long term is weak.
- Trial name
- MPH (NCT02754258)
- Testing
- MPH
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Depression
Study of Methylphenidate as Add on Therapy in Depressed Cancer Patients
Primary Objective To determine the efficacy of Methylphenidate as add on therapy to mirtazapine in the treatment of depression in cancer patients under palliative care Hypothesis Methyphenidate add on to mirtazapine treated…
- Trial name
- NCT01497548
- Testing
- Methylphenidate
- Where
- 2 sites in Malaysia
- Volunteers
- 120 people
- Sponsor
- University of Malaya
Substance Use Disorder, Cocaine Use Disorder
Targeting Drug Memories With Methylphenidate
This study aims to identify the neural, behavioral, and pharmacological mechanisms promoting diminished expression of drug-related memories in human drug addiction.
- Trial name
- NCT05978167
- Testing
- Methylphenidate, Memory reconsolidation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
ADHD - Attention Deficit Disorder With Hyperactivity, Fibromyalgia (FM)
Comorbidity Between Attention Deficit Hyperactivity Disorder and Fibromyalgia
The overall objective of the research project presented here is to assess the prevalence of fibromyalgia in patients being treated for ADHD, the prevalence of ADHD in patients being treated for fibromyalgia, and the…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Fibromyalgia (FM), Chronic Pain
- Trial name
- HYPERPAIN (NCT07443800)
- Testing
- Samples, Questionnaires, Sensitivity to mechanical pain
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Mild Cognitive Impairment
Ritalin, Memory and Attention in MCI: a Behaviour-EEG Study
Traditionally, memory impairments in the elderly population are treated using cholinesterase inhibitors, although impairments remain after treatment.
- Trial name
- NCT02326038
- Testing
- Methylphenidate
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Attention-deficit/Hyperactivity Disorder
Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
The purpose of this study is to determine effectiveness of Vyvanse compared to Concerta in adolescents with Attention-deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT01552915
- Testing
- Lisdexamfetamine dimesylate, Methylphenidate Hydrochloride
- Where
- 79 sites in United States
- Volunteers
- 464 people
- Sponsor
- Shire
Attention Deficit/ Hyperactivity Disorder
A Study to Evaluate Effectiveness and Safety of Prolonged Release OROS Methylphenidate in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the efficacy of 2 fixed dosages of Prolonged Release (PR) OROS methylphenidate (54 and 72 mg/day) compared with placebo in adult patients with attention deficit/hyperactivity disorder…
- Trial name
- NCT00714688
- Testing
- prolonged release (PR) OROS methylphenidate 54 mg, prolonged release (PR) OROS methylphenidate 72 mg
- Where
- 42 sites in Belgium, Denmark and 9 more
- Volunteers
- 279 people
- Sponsor
- Janssen-Cilag International NV
ADHD
Multimodal Magnetic Resonance Imaging Study on the Neural Mechanisms of Remission in Children With ADHD
Attention-deficit/hyperactivity disorder(ADHD) is highly prevalent among children and adolescents and often associated with poor long-term outcomes in adulthood. it is thus a serious public health problem.
- Trial name
- NCT05229627
- Testing
- MPH, ATX
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Attention Deficit Hyperactivity Disorder, Sleep Onset Insomnia
Comparing Treatment With Melatonin to Treatment With Stimulants (Methylphenidate) in Children With Attention Deficit Hyperactivity Disorder and Sleep Difficulties
The study hypothesis is that some children with Attention-Deficit-Hyperactivity-Disorder (ADHD) who also have sleep onset difficulties will improve with Melatonin treatment to an extent similar to that of stimulants treatment.
- Trial name
- NCT01393574
- Testing
- Melatonin, Methylphenidate
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Assaf-Harofeh Medical Center
Attention Deficit Disorder With Hyperactivity
Concerta (Methylphenidate) -To-Generic Switch Study
The primary purpose of this study is to identify whether, after adjustment for confounders via stratification on a propensity score and adjustment for calendar year, the combined endpoint consisting of #1 to #4 (1.
- Trial name
- NCT02730572
- Testing
- Concerta, Concerta AG formulation, Concerta EG formulation
- Volunteers
- 1,464 people
- Sponsor
- Janssen Research & Development, LLC
Attention Deficit Hyperactivity Disorder, ADHD
Genetic Measurements in Blood Cells of Children Taking Adderall or Methylphenidate
This study, conducted at Duke University in Durham, NC, will determine whether the drugs Adderall and methylphenidate affect the genetic material of children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT00341029
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Brain Injuries
Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery
Traumatic Brain Injury (TBI) is the leading cause of acquired long term disability among children and young adults. Deficits in attention and memory are common and persist for years after moderate or severe TBI.
- Trial name
- NCT00035139
- Testing
- methylphenidate
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)