Clinical trials: Methylphenidate
ADHD
Virtual Reality a Novel Screening and Treatment Aid in Attention Deficit Disorder
Using a virtual reality program in screening and treatment of ADHD.
- Trial name
- NCT00364702
- Testing
- methylphenidate
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Attention Deficit Hyperactivity Disorder, ADHD
Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD
This multi-center parallel study is designed to study the efficacy and safety of fixed doses of methylphenidate extended release (ER) capsules of four dose levels compared with a placebo group in pediatric patients with Attention…
- Trial name
- NCT01239030
- Testing
- Methylphenidate Hydrochloride Extended Release Capsules
- Where
- 16 sites in United States
- Volunteers
- 230 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Attention Deficit Disorder With Hyperactivity
An Efficacy and Safety Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the safety and efficacy of Osmotic Release Oral System (OROS) methylphenidate in participants with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01012622
- Testing
- Osmotic Release Oral System (OROS) Methylphenidate Hydrochloride
- Volunteers
- 142 people
- Sponsor
- Janssen Korea, Ltd., Korea
ADHD
Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD
To assess the efficacy and safety of efficacy of MTS compared to placebo
- Trial name
- NCT00499863
- Testing
- methylphenidate transdermal system
- Where
- 32 sites in United States
- Volunteers
- 217 people
- Sponsor
- Noven Therapeutics
Healthy
Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults
There are two specific aims of this study. The first is to document the pharmacokinetics of dopamine transporter (DAT) receptor occupancy of repeated administration of orally administered, therapeutic doses of a short immediate…
- Trial name
- NCT00302393
- Testing
- OROS methylphenidate hydrochloride, methylphenidate hydrochloride
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Brain Connectivity in Attention Deficit Hyperactivity Disorder (ADHD)
This study investigates whether a relationship exists between pre-treatment brain characteristics and treatment response in adults with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- BCADHD (NCT03709940)
- Testing
- MPH
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Brain Tumor, Pediatric, Cancer-related Fatigue
Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue
Cancer-related fatigue is a common and debilitating late effect in pediatric brain tumor survivors. Currently, evidence-based recommendations to ameliorate this condition are lacking.
- Conditions
- Brain Tumor, Pediatric, Cancer-related Fatigue, Methylphenidate
- Trial name
- EMBRAIN (NCT06905587)
- Testing
- Methylphenidate (MPH)
- Where
- 4 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
PTSD, Stroke
Methylphenidate for Ptsd and Stroke Veterans
Veterans with post-traumatic stress disorder (PTSD) have an increased risk of developing ischemic stroke. Veterans enduring PTSD face difficulties in managing their PTSD severity after suffering from a stroke.
- Trial name
- NCT04885257
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Emotional Dysregulation, Externalizing Problems
Assessing Real Life Effectiveness of Treatment in Neurodevelopmental Disorders
The goal of this observational study is to learn if and how pharmacological and psychotherapeutic group treatments can treat clinical symptoms of children and adolescent patients with ADHD.
- Conditions
- Emotional Dysregulation, Externalizing Problems, Oppositional Defiant, Conduct Disorder
- Trial name
- ALERT (NCT07273695)
- Testing
- methyphenidate, Group psychological treatment
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Eugenio Medea
Attention Deficit Hyperactivity Disorder (ADHD), Attention Deficit Hyperactivity Disorder
A 6-week Study to Evaluate the Safety and Efficacy of Quillichew ERCT in 4-5 Year Old Children With ADHD.
A 6-week double-blind study to evaluate the safety and efficacy of Quillichew extended release chewable tablets in 4-5 year old children with attention deficit hyperactivity disorder.
- Trial name
- NCT03580005
- Testing
- methylphenidate HCl ERCT
- Sponsor
- Pfizer
Attention Deficit Disorder With Hyperactivity
Methylphenidate in Adults With Attention Deficit/Hyperactivity Disorder
Methylphenidate (MPH) is the first-line pharmacological treatment for adults with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT02951754
- Testing
- Immediate-release Methylphenidate
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
ADHD
Multimodal Brain Imaging of Methylphenidate in Children and Adolescents With ADHD
The goal of this proposal is to develop brain imaging tools to measure the effects of methylphenidate in children and adolescents with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT06077669
- Testing
- Methylphenidate
- Where
- United States
- Sponsor
- Johns Hopkins University
ADHD
Cognitive Remediation in ADHD Children : Comparison Between Three Therapeutic Strategies : Cognitive Remediation With a Virtual Classroom Software and Methylphenidate and Supportive Psychotherapy
The Attention Deficit Disorder with or without Hyperactivity (ADHD) is one of the most frequently found disorder in children. It is characterized by a triad of symptoms involving attention deficit, hyperactivity and impulsivity…
- Trial name
- RECOGNITA (NCT01821170)
- Testing
- Methylphenidate, cognitive remediation, supportive psychotherapy
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Attention Deficit Hyperactivity Disorder
Efficacy and Effectiveness of Methylphenidate in Swedish Male Prison Inmates With Attention-deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the efficacy and effectiveness of methylphenidate in treatment of ADHD in Swedish adult male prison inmates diagnosed with ADHD.
- Trial name
- NCT00482313
- Testing
- PR OROS Methylphenidate
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Psychiatry Karolinska
Healthy Volunteers
A Double-blind Randomized, Placebo-controlled, Crossover Study of Single Doses of OROS Methylphenidate Hydrochloride (CONCERTA) and Long-acting Methylphenidate Hydrochloride (RITALIN LA) in Healthy Adults
This is a double-blind, placebo-controlled study, three-period crossover study to examine the likeability of a single dose of OROS MPH (CONCERTAÒ 90mg) and a single dose of Long-acting MPH (RITALIN LAÒ 90mg).
- Trial name
- NCT00302354
- Testing
- OROS methylphenidate HCl, SODAS methylphenidate HCl
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder
Pharmacokinetics of Two Extended-Release Formulations of Methylphenidate in Children With Attention Deficit Hyperactivity Disorder (ADHD)
This study is designed to provide pharmacokinetic data for the assessment of bioequivalence of Ritalin LA formulation compared to Medikinet ret. concerning plasma levels and efficacy measures.
- Trial name
- MPH-Kinetics (NCT00772161)
- Testing
- Methylphenidate
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Freiburg
Attention Deficit Hyperactivity Disorder
PK/PD Pediatric ADHD Classroom Study
The purpose of this study is to evaluate the association between blood drug levels and the corresponding scores of commonly used behavioral instruments based upon data collected following administration of three different…
- Trial name
- NCT02536105
- Testing
- Methylphenidate HCl ER tablets 1, Methylphenidate HCl ER tablets 2, Methylphenidate HCl ER for suspension
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Massachusetts General Hospital
Parkinson's Disease
The Effect of Methylphenidate on Non-motor Symptoms and Postural Control in Parkinson's Disease.
This project aims to determine if methylphenidate can improve deficits in attention and symptoms of orthostatic hypotension, two common non-motor symptoms, in patients with Parkinson's Disease.
- Trial name
- NCT01244269
- Testing
- Methylphenidate
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- Laval University
Substance Abuse
Methylphenidate Studies for Drug Abuse Vulnerability Molecular Genentics
Background: Research has shown that several human genes have been associated with vulnerability to substance abuse and dependence.
- Trial name
- NCT00247689
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Drug Interaction
Cannabidiol and CES1 Interactions in Healthy Subjects
The proposed study will assess the drug interaction potential between oral cannabidiol (Epidiolex®) and the carboxylesterase 1 (CES1) substrate methylphenidate (Ritalin®) in 12 healthy research subjects
- Trial name
- NCT04603391
- Testing
- dl-Methylphenidate plus Cannabidiol
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Florida