Clinical trials: Methylphenidate
Depression
Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression
This study will evaluate the safety and effectiveness of methylphenidate in improving cognition and function in older adults with depression.
- Trial name
- NCT00602290
- Testing
- Citalopram, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, Los Angeles
Attention Deficit Disorder With Hyperactivity, Tourette Syndrome
Methylphenidate for Treating Children With ADHD and Tourette Syndrome
This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder in children with both attention deficit hyperactivity disorder and Tourette syndrome.
- Trial name
- NCT00441649
- Testing
- Methylphenidate
- Volunteers
- 71 people
- Sponsor
- Stony Brook University
Traumatic Brain Injury, TBI
Methylphenidate for Attention Problems After Pediatric TBI
Traumatic Brain Injury (TBI) - methylphenidate treatment
- Conditions
- Traumatic Brain Injury, TBI, ADHD
- Trial name
- NCT01933217
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Alzheimer Dementia
A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.
Investigators are doing this research study to find out if methylphenidate (MPH) can help people with Mild Cognitive Impairment (MCI) or mild dementia likely due to Alzheimer's Disease (AD) and related disorders (ADRD).
- Trial name
- NCT03811847
- Testing
- Methylphenidate Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Alcohol Use Disorder, Attention Deficit Hyperactivity Disorder
Methylphenidate and Response to Alcohol Cues Pilot Study
The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues.
- Trial name
- NCT06063200
- Testing
- Methylphenidate Pill
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson's Disease, Idiopathic
TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Disease
Gait and balance problems are a significant source of disability in patients with Parkinson disease. Physical therapy remains one of the main treatments.
- Trial name
- TAME-PD (NCT02879136)
- Testing
- Methylphenidate, Physical Therapy, Atomoxetine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Hubert Fernandez
Acquired Brain Injury
Effect of Methylphenidate on Ecologic Function in Paediatric Acquired Brain Injury Population
The purpose of this study is to investigate the influence of Methylphenidate in pediatric acquired brain injury population, regarding ecologic (every day) function.
- Trial name
- NCT02227056
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Loewenstein Hospital
Attention Deficit Hyperactivity Disorder
Further Studies of Attention Deficit Disorder - Residual Type (RT)
The first phase was a double-blind crossover design of methylphenidate in the treatment of adult ADHD. The second phase consisted of an open-label extension trial of methylphenidate in adult ADHD.
- Trial name
- NCT00693212
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Utah
Attention Deficit Disorder With Hyperactivity
Clonidine in Attention Deficit Hyperactivity Disorder (ADHD) in Children
The purpose of this study is to determine the safety and efficacy of clonidine alone or in combination with methylphenidate for children 7-12 years of age with attention-deficit, hyperactivity disorder.
- Trial name
- NCT00031395
- Testing
- clonidine, methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Cincinnati
Attention Deficit Hyperactivity Disorder
OROS Methylphenidate (Concerta) in the Treatment of Adult ADHD
This study will look at the effectiveness of osmotic release oral system (OROS) methylphenidate (Concerta) in treating attention deficit hyperactvity disorder (ADHD) in adults.
- Trial name
- NCT02215538
- Testing
- OROS methylphenidate
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Healthy
A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunteers
This is a drug-drug interaction study; the purpose of this study is to examine the pharmacokinetics (levels of drug in the blood) of SPD503 (guanfacine hydrochloride) and Concerta (methylphenidate HCl) when given alone, and in…
- Trial name
- NCT00901576
- Testing
- SPD503, Concerta, SPD503 + Concerta
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shire
Healthy, Attention Deficit Hyperactivity Disorder
Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
The goal of this research is to understand the functioning of 'regulatory circuits' in the brain. We are also interested in how the medications methylphenidate and naltrexone affect these regulatory circuits.
- Trial name
- NMAS (NCT01993108)
- Testing
- Methylphenidate, Naltrexone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
ALL, Childhood, Leukemia, Lymphoblastic
Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors
While neurocognitive impairments in attention, memory and executive functioning are commonly reported sequelae of childhood leukemia and brain tumors, studies have only recently begun to examine the treatment of attention…
- Conditions
- ALL, Childhood, Leukemia, Lymphoblastic, Leukemia, Lymphoblastic, Acute, Leukemia, Lymphoblastic, Acute, L1
- Trial name
- NCT01100658
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Minnesota
Attention Deficit Hyperactivity Disorder
A Study in Attention Deficit Hyperactivity Disorder in Children and Adolescents
The main purpose of the study is to help to understand the effect on children and adolescents who are stable on treatment with atomoxetine or osmotic-release oral system (OROS) methylphenidate for attention-deficit/hyperactivity…
- Trial name
- EMD (NCT01127646)
- Testing
- Atomoxetine, Osmotic-release oral system methylphenidate
- Where
- 14 sites in Netherlands, Spain and 1 more
- Volunteers
- 23 people
- Sponsor
- Eli Lilly and Company
Attention Deficit/Hyperactivity Disorder
Cost-effectiveness of the Treatment of Attention Deficit/Hyperactivity Disorder With Methylphenidate Immediate-release in Brazil
The first objective is to measure the QALYs (Quality Adjusted Life Years) of Brazilian children and adolescents, submitted to methylphenidate immediate-release treatment for Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01705613
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Attention Deficit Disorder With Hyperactivity
Adherence and Long-term Effect of OROS Methylphenidate (CONCERTA): A Follow-up Study
The objectives of this study are to investigate: 1. the evolution of ADHD symptoms, remission rate of ADHD, social and school function, and familial relationship; 2.
- Trial name
- NCT00598182
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan University Hospital
Traumatic Brain Injury
Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
Deficits in memory, attention, cognitive, and executive functions are the most common disabilities after traumatic brain injury (TBI).
- Trial name
- NCT02148783
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Uniformed Services University of the Health Sciences
ADHD
The Relationship Between CES1 Genotype and Methylphenidate Response in Children With ADHD - INDICES Work Package 6
This is a prospective observational study of a cohort of children diagnosed with Attention Deficit Hyperactive Disorder (ADHD) and followed with weekly assessments during the first 12 weeks of Methylphenidate (MPH) treatment, and…
- Trial name
- NCT04366609
- Testing
- Methylphenidate
- Volunteers
- 207 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Adhd
The Study of Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original
This study is a cross-over trial, design to determine the efficacy and safety of generic and original prolong-release methylphenidate (PR-MPH) in children with ADHD who had received immediate-release methylphenidate treatment
- Trial name
- NCT05410626
- Testing
- prolong-release methylphenidate
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Epilepsy
Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
Methylphenidate (MPH) is a stimulant, FDA-approved for the treatment of attention deficit hyperactivity disorder (ADHD). It is unknown, however, if stimulants would be of benefit for memory and thinking problems due to epilepsy.
- Trial name
- NCT04419272
- Testing
- Methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development