Clinical trials: Methylphenidate
Attention Deficit Hyperactivity Disorder
Omega-3 Supplementation and Attention-deficit-hyperactivity Disorder (ADHD)
It is assumed that only 1/5 of children diagnosed with attention-deficit-hyperactivity disorder (ADHD) are treated. New treatment modalities are urgently needed.
- Trial name
- NCT00874536
- Testing
- omega-3 fatty acid alpha-linolenic acid (ALA)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Cocaine Addiction, Cocaine Abuse
Psychology of Reward and Punishment: Functional and Molecular Brain Imaging and Monoaminergic Correlates
Background: Brain imaging studies, genetic research, and investigations of stress have provided more information about the role of dopamine in processing reward and punishment, and in vulnerability to substance dependence.
- Trial name
- NCT00865332
- Where
- 2 sites in United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Attention Deficit Hyperactivity Disorder
Methylphenidate Transdermal System (MTS) in the Treatment of Adult ADHD
This study will look at the effectiveness of Methylphenidate Transdermal System (MTS) in treating adult ADHD. MTS has received FDA approval for childhood ADHD but this is the first trial for adult ADHD.
- Trial name
- NCT00506285
- Testing
- Methylphenidate Transdermal System (MTS)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Utah
Pharmacokinetics
A Study to Explore Plasma Levels of CONCERTA, Ritalin-SR and Novo-Methylphenidate ER-C in Healthy Volunteers
This is a study of blood plasma levels of methylphenidate in healthy volunteers over a 24 hour period after they take this medication.
- Trial name
- NCT01118702
- Testing
- Ritalin-SR, Concerta, Novo-Methylphenidate ER-C
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Janssen-Ortho Inc., Canada
Attention Deficit Disorder With Hyperactivity
A Study on Suicidality, Psychosis or Substance Abuse With Methylphenidate, Atomoxetine, Amphetamine/Dextroamphetamine or Lisdexamfetamine
The purpose of this study is to estimate the observed incidence of the health outcomes (suicide attempt or ideation, suicide ideation, suicide attempt, psychosis, and substance abuse) in a cohort of participants diagnosed with…
- Trial name
- NCT04132557
- Testing
- Methylphenidate, Lisdexamfetamine, Atomoxetine
- Where
- United States
- Volunteers
- 430,000 people
- Sponsor
- Janssen Research & Development, LLC
Attention Deficit Hyperactivity Disorder
Dextromethorphan Added on for the Patients With ADHD
Dextromethorphan added on methylphenidate for the patients with attention deficit hyperactivity disorder
- Trial name
- DAOFTPWA (NCT01787136)
- Testing
- Dextromethorphan
- Sponsor
- Tri-Service General Hospital (TSGH)
BD
The Effect of Methylphenidate on Cognitive Abilities of Adults With Bipolar Disorder
The purpose of the study is to explore the effect of MPH on working memory, attention and decision making in adults with BD in remission or in depressed state.
- Trial name
- NCT02020200
- Testing
- MPH
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Shalvata Mental Health Center
Attention-Deficit/Hyperactivity Disorder (ADHD)
Efficacy and Safety of Dex-Methylphenidate Extended Release 30 mg Versus 20 mg in Children (6-12 Years) With Attention-Deficit/Hyperactivity Disorder (ADHD) in a Laboratory Classroom Setting.
This study will evaluate the efficacy and safety of Dex-Methylphenidate Extended Release 30 mg compared to 20 mg in pediatric patients ages 6-12 with Attention-Deficit Hyperactivity Disorder (ADHD) in a 12-hour laboratory…
- Trial name
- NCT00776009
- Testing
- Dex-Methylphenidate hydrochloride Extended Release (Focalin® XR)
- Where
- 8 sites in United States
- Volunteers
- 165 people
- Sponsor
- Novartis Pharmaceuticals
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Methylphenidate in Treating Patients With Fatigue Caused by Cancer
RATIONALE: Methylphenidate may help relieve fatigue caused by cancer. It is not yet known whether methylphenidate is more effective than a placebo in relieving fatigue and improving quality of life in patients with cancer.
- Trial name
- NCT00376675
- Testing
- methylphenidate hydrochloride
- Where
- 238 sites in United States
- Volunteers
- 148 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Attention Deficit Hyperactivity Disorder
The Effect of Methylphenidate on Decision-making Ability of Attention Deficit Hyperactivity Disorder (ADHD) Adults
The aim of the study is to assess the effect of Methylphenidate on cognitive performance and decision-making ability of ADHD adults, and to compare this effect to the effect on healthy control adults.
- Trial name
- NCT01040702
- Testing
- methylphenidate, sweetener pill
- Where
- Israel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Delayed Emergence From Anesthesia
General Anesthesia Emergence Induced by Methylphenidate
The purpose of this study is to assess whether methylphenidate affects time of emergence from isoflurane general anesthesia. Time to emergence was defined as the time from termination of isoflurane to extubation.
- Trial name
- MPOrtho (NCT02327195)
- Testing
- Methylphenidate HCl
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nicoleta Stoicea
ADHD
Benefits of ADHD Treatment in Detained People
Attention deficit hyperactivity disorder (ADHD) is characterized by difficulties paying attention, poor impulse control, and hyperactive behaviors.
- Trial name
- BATIR (NCT05842330)
- Testing
- Concerta
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Stéphanie Baggio
Attention Deficit Hyperactivity Disorder
Long-term Safety and Effectiveness of OROS Methylphenidate HCl in Children With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the long-term safety and effectiveness of OROS® Methylphenidate HCl (a central nervous system stimulant) in children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT00269815
- Testing
- methylphenidate HCl
- Sponsor
- Alza Corporation, DE, USA
Attention Deficit Hyperactivity Disorder
Placebo-Controlled Multi-Centre Double-Blind Trial for Adults With Extended-Release Methylphenidate for ADHD
Investigation of efficacy and tolerability of extended-release MPD in adults with ADHD, compared with a placebo, and to acquire knowledge through long-term observation of adults
- Trial name
- EMMA (NCT00619840)
- Testing
- methylphenidate hydrochloride
- Where
- Germany
- Volunteers
- 363 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Fatigue in Multiple Sclerosis
Testing the Effects of Methylphenidate on Multiple Sclerosis
Up to 95% of individuals with Multiple Sclerosis report experiencing cognitive fatigue, characterized by a lack of energy, feelings of exhaustion, an the perception that one is unable to partake in daily activities.
- Trial name
- NCT02286557
- Testing
- Methelphenidate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kessler Foundation
Disruptive Mood Dysregulation Disorder
Aripiprazole Added on for DMDD in Youths With ADHD
Objectives: 1. To investigate the effectiveness of adjuvant with aripiprazole to methylphenidate for disruptive mood dysregulation disorder (DMDD) in youths with attention-deficit/hyperactivity disorder (ADHD) 2.
- Trial name
- AAOFDIYWA (NCT03358277)
- Testing
- MPH + APZ
- Volunteers
- 58 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Attention Deficit Hyperactivity Disorder
Study of the Effects of Osmotic-Release Oral System (OROS) Methylphenidate (Concerta) on Attention and Memory
This study investigates whether OROS-methylphenidate improves performance on different aspects of attention and memory in children with Attention-Deficit Hyperactivity Disorder (ADHD).
- Trial name
- CHOP (NCT00530257)
- Testing
- OROS-methylphenidate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Philadelphia
Attention Deficit Hyperactivity Disorder (ADHD), Obesity (Body Mass Index &Amp;Amp;gt;30 kg/m2)
PHArmaCokinetics of methYLphenidate in Adult Patients With Attention-Deficit /Hyperactivity Disorder
PHACYLOB PHArmaCokinetics of methYLphenidate in adult patients with Attention-Deficit Hyperactivity Disorder (ADHD) : comparison between patients with and without OBesity.
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Obesity (Body Mass Index &Amp;Amp;gt;30 kg/m2), Methylphenidate, Obesity &Amp; Overweight
- Trial name
- PHACYLOB (NCT07121621)
- Testing
- PHArmacoKinetics of methYLphenidate in adult patients with ADHD: comparison between patients with and without OBesity.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Tours
Drug Abuse
The Effects of Expectation on Natural and Drug -Induced Rewards
Background: Environmental cues frequently induce expectancies in individuals that may strongly influence the actual experience associated with the cue.
- Trial name
- NCT01036230
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Attention-deficit/Hyperactivity Disorder
Cost-Effectiveness Study Of The Treatment Of Attention Deficit/Hyperactivity Disorder In Brazil
This study is an open-label, 6 month trial, of immediate release methylphenidate (MPH-IR) for children with ADHD aimed at assessing whether the observable behavioral changes seen during treatment are associated with potentially…
- Trial name
- NCT01228604
- Testing
- methylphenidate (Ritalin®)
- Where
- Brazil
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre