Clinical trials: Methylphenidate
Mild Cognitive Impairment (MCI)
The Effects of Methylphenidate on the Cognitive Function of Older People With Mild Cognitive Impairment
Background: The increase in life expectancy and the rise in the ratio of older to younger people in the population has resulted in an increase in the number of those suffering from a decrease in cognitive ability, such as Mild…
- Trial name
- NCT02180529
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Meir Medical Center
Attention Deficit Disorder With Hyperactivity
Effects of Ritalin on Postural Stability of Hyper Active Children
Experimental design overview The proposed project is a prospective experimental study design. Children (age <15) suffer from attention deficit hyperactivity disorder (ADHD) that their Parents willing to participate in the study…
- Trial name
- NCT00485797
- Testing
- Ritalin
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Attention Deficit Hyperactivity Disorder (ADHD)
Safety, Tolerability and PK Study of Methylphenidate HCl ERCT in 4-5 Year Old Children With ADHD.
2-week open-label safety, tolerability and pharmacokinetic study of methylphenidate HCl ERCT in 4-5 year old children with ADHD.
- Trial name
- NCT03546400
- Testing
- methylphenidate HCl ERCT
- Sponsor
- Pfizer
Visual Field Tests
Methylphenidate Effect on Humphrey Visual Fields
Study will include adults with abnormal visual fields. Half of them will be given either methylphenidate 10mg 2 hours before repeating the visual field test. the rest will serve as controls.
- Trial name
- NCT02162381
- Testing
- methylphenidate, guidance
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Rabin Medical Center
ADHD, Attention Deficit Hyperactivity Disorder
A Study of Combination Therapy in Children With ADHD
Lack of appetite and weight loss are a common side effect of ADHD therapy with amphetamines such as methylphenidate. Lack of sufficient food intake has been shown to have negative effects on weight and height as well as learning…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood
- Trial name
- NCT01940978
- Testing
- Methylphenidate ER, Cyproheptadine
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Douglas Sears
Attention Deficit Hyperactivity Disorder
A Study of Dex-methylphenidate Extended Release in Children (6-12 Years) With Attention-Deficit/Hyperactivity Disorder (ADHD)
This study compared the efficacy of dex-methylphenidate extended release 20 mg versus placebo during an 8-hour laboratory classroom day.
- Trial name
- NCT00564954
- Testing
- Dex-methylphenidate hydrochloride extended-release (Focalin XR)
- Where
- 5 sites in United States
- Volunteers
- 86 people
- Sponsor
- Novartis Pharmaceuticals
Cancer
Methylphenidate for Cancer-Related Fatigue
The overall aim of this pilot study is to conduct a combined N-of-1 trial (N-1-T) of MPH (methylphenidate) for amelioration of fatigue in children with cancer, and to evaluate the N-1-T design both for individual clinical…
- Trial name
- NCT01164956
- Testing
- methylphenidate
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Dana-Farber Cancer Institute
Cocaine Use Disorder
Behavioral Effects of Drugs: Inpatient (35)
This study will determine the influence of methylphenidate (Metadate®) and duloxetine (Cymbalta®), alone and in combination, on the reinforcing, subjective and physiological effects of cocaine.
- Trial name
- BED IN 35 (NCT03519022)
- Testing
- Cocaine, Methylphenidate
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Craig Rush
Methylphenidate
Methylphenidate (Ritalin®) Effect During Exposure to Exercise and Heat Stress in ADD/ADHD Treated Patients
The purpose of this study is to explore the possible effects of MPH use on physiological functions among ADHD\ADD patients, by performing a set of physical trials to assess aerobic and anaerobic capacity, to characterize the…
- Trial name
- NCT02704546
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Attention Deficit Hyperactivity Disorder
Effects of Methylphenidate on Cellular Abnormalities in Children With Attention Deficit Hyperactivity Disorder (ADHD)
This study will assess the frequency of chromosomal abnormalities measured in circulating lymphocytes in treatment-naive children with Attention Deficit Hyperactivity Disorder (ADHD) treated for 3 months with either extended…
- Trial name
- NCT00409708
- Testing
- Extended Release Methylphenidate (Ritalin LA ) plus Behavior Therapy, Behavior Therapy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Novartis
Healthy
Emotional Effects of Methylphenidate and MDMA in Healthy Subjects
This study compares the interactive emotional/subjective effects of single doses of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and methylphenidate, a dopamine (DA) and norepinephrine (NE) transporter blocker, in healthy…
- Trial name
- NCT01465685
- Testing
- 3,4-Methylenedioxymethamphetamine, Methylphenidate
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postural Imbalance
Effects of Ritalin on Postural Stability of Old Adults
Experimental design overview The proposed project is a prospective experimental study design. independent old adults(age 65 years old and older) who do not suffer from balance problems willing to participate in the study will be…
- Trial name
- NCT00817960
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Attention-deficit/Hyperactivity Disorder, Autism Spectrum Disorder
Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD
The purpose of this study is to determine whether methylphenidate hydrochloride extended release liquid formulation is safe and effective in the treatment of attention-deficit/hyperactivity disorder (ADHD) in high-functioning…
- Trial name
- NCT02096952
- Testing
- Methylphenidate extended-release liquid formulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Methamphetamine Dependence
Methylphenidate to Treat Methamphetamine Dependence
This 4-year study will investigate the effectiveness of methylphenidate for initiating and sustaining abstinence in methamphetamine dependent individuals.
- Trial name
- MPH (NCT01044238)
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Multiple Sclerosis, Fatigue
Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis
Fatigue is a common symptom in multiple sclerosis (MS) that is characterized by physical and/or mental exhaustion. Fatigue is difficult to treat and treatment efficacy of available therapy is limited.
- Trial name
- MS (NCT01879202)
- Testing
- Methylphenidate modified release, Maltodextrin
- Where
- Austria
- Volunteers
- 96 people
- Sponsor
- Medical University of Vienna
Social Cognition
Effects of MDMA and Methylphenidate on Social Cognition
The purpose of this study is to assess and compare the effects of a single dose of 3,4-methylenedioxymethamphetamine (MDMA)and methylphenidate (MPH) on emotional and social cognition in healthy subjects.
- Trial name
- NCT01616407
- Testing
- 3,4-Methylenedioxymethamphetamine, Methylphenidate
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Prostate Carcinoma
Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer
This phase II/III trial studies how well methylphenidate and exercise work in reducing cancer-related fatigue in patients with prostate cancer.
- Trial name
- NCT03772834
- Testing
- Exercise Intervention, Methylphenidate, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Attention Deficit Disorder With Hyperactivity
Efficacy, Safety and Tolerability of SPD485 in Children Aged 6-12 Diagnosed With ADHD
This study will assess the efficacy, duration of effect, tolerability and safety of 4- and 6- hour wear times of SPD485 in 6-12 year old subjects diagnosed with ADHD.
- Trial name
- NCT00151970
- Testing
- Methylphenidate Transdermal System, Concerta
- Volunteers
- 128 people
- Sponsor
- Noven Therapeutics
Attention Deficit Disorder With Hyperactivity
Classroom Study to Assess Efficacy and Safety of MTS in Pediatric Patients Aged 6-12 With ADHD
Evaluate the behavioral effects of MTS in children aged 6-12 with ADHD
- Trial name
- NCT00466791
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Noven Therapeutics
Attention Deficit Disorder With Hyperactivity
Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children
This study will determine the effectiveness of stimulant and nonstimulant medication in treating the symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents.
- Trial name
- NCT00183391
- Testing
- Atomoxetine, Methylphenidate
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- Icahn School of Medicine at Mount Sinai