Clinical trials: Metoclopramide
PREGNANCY
Prophylactic Subhypnotic Propofol for Nausea and Vomiting During for Cesarean Section Under Subarachnoid Anesthesia.
Perioperative nausea and vomiting may occur in 50-80% of patients undergoing cesarean section. Metoclopramide is a well known Dopamine receptor antagonist that acts at the Chemoreceptor trigger zone and is used effectively for…
- Trial name
- NCT01781377
- Testing
- PROPOFOL, METOCLOPRAMIDE
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- G. d'Annunzio University
Acute Upper Gastrointestinal Bleeding, Effect of Drug
Metoclopramide for Acute Upper GI Bleeding
The presence of blood clot in stomach limited quality of endoscopic view ,which affect successful rate of hemostatic endoscopy in patient with acute upper gastrointestinal bleeding.
- Trial name
- NCT04771481
- Testing
- Metoclopramide, Normal Saline 10 mL Injection
- Where
- 2 sites in Thailand
- Volunteers
- 68 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Migraine Disorders
Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache
The purpose of this study is to determine which drug makes lower migraine headache
- Trial name
- NCT01791400
- Testing
- metoclopramide, injection,20mg, one time, Sumatriptan, injection, 6 mg, one time
- Where
- Iran
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Pill Capsule Endoscopy Completion Rates
Study of Metoclopramide in Small Bowel Capsule Endoscopy
Patients undergoing small bowel capsule endoscopy will be randomized into 3 study groups to either receive 5 mg of metoclopramide, 10 mg of metoclopramide, or a placebo 30 minutes prior to swallowing the Pill Cam.
- Trial name
- NCT01630109
- Testing
- Metoclopramide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Ascension Health
Hyperemesis Gravidarum
Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum
The investigators will compare the effectiveness of gabapentin to metoclopramide for 1 week among 60 women with hyperemesis gravidarum (HG) in this randomized, double-blinded trial.
- Trial name
- NCT02163434
- Testing
- Gabapentin, Metoclopramide
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Duration of Labour
Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour
BACKGROUND Prolonged labour can lead to increased maternal and neonatal mortality and morbidity. The risk for complications of prolonged labour is more in poor resource settings.
- Trial name
- NCT05222646
- Testing
- Metoclopramide
- Where
- Nigeria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uwakwe Emmanuel Chijioke
Nausea, Vomiting
Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due to Vertigo
Vertigo complaint is one of the common cause of patients who applied to emergency services. Patients who have applied to emergency services with vertigo complaint mostly have nausea as an additionally symptom to this complaint…
- Conditions
- Nausea, Vomiting, Vertigo
- Trial name
- NCT02253524
- Testing
- Dimenhydrinate, Metoclopramide
- Volunteers
- 200 people
- Sponsor
- Pamukkale University
Peripheral Vertigo
Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo.
Background: Vertigo as acute symptom seem to be one of most common presentation in ED, can be treated in ED with multiple medication .
- Trial name
- BBPVOMSBAFH (NCT05586763)
- Testing
- Metoclopramid ( 10mg), IM promethazine (25mg) , IM prochloroperazine( 12.5mg)
- Where
- Oman
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Pregnancy, PONV
Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section
Post-operative nausea and vomiting are the major complications after spinal anesthesia with intrathecal morphine, therefore antiemetic drugs should be administered for best satisfaction of anesthesia to prevent these…
- Trial name
- NCT00892996
- Testing
- dexamethasone, dexamethasone 5 mg
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cesarean Delivery
Prevention of Intraoperative Nausea and Vomiting During Cesarean Section
The study investigates the incidence of intraoperative nausea and vomiting under spinal anesthesia using a phenylephrine infusion with and without prophylactic antiemetics.
- Trial name
- NCT01216410
- Testing
- Metoclopramide, Phenylephrine infusion, Combination Group
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- Duke University
Nausea and Vomiting, Postoperative
Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy
Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy
- Trial name
- NCT04899817
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Migraine
Valproate Versus Ketorolac Versus Metoclopramide
This randomized study is testing 3 different intravenous medications to see which one is best for acute migraine. The three medications are metoclopramide, valproate, and ketorolac.
- Trial name
- NCT01267864
- Testing
- Metoclopramide, Ketorolac, Valproate
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Montefiore Medical Center
Patients Attending Hospital for Small Bowel Endoscopy
Can Steerable Capsule Endoscopy Enhance Gastric Emptying?
Small bowel wireless capsule endoscopy is the investigation modality of choice for suspected diseases of the small bowel. The procedure is safe and noninvasive, the main risk being capsule retention occurring in approximately 2%…
- Trial name
- NCT02282852
- Testing
- Wireless Capsule Endoscopy, Magnetically steerable capsule endoscopy
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Gastroesophageal Reflux
Methoclopramide for Gastroesophageal Reflux in Premature Infants
Gastroesophageal Reflux (GER) is a condition that affects the majority of premature infants that are followed at the Kangaroo Mother Care Program (ambulatory program for preterm infants discharged with their mothers in continuous…
- Trial name
- NCT02907632
- Testing
- Metoclopramide
- Where
- Colombia
- Volunteers
- 490 people
- Sponsor
- Nathalie Charpak
Radiation Exposure, Enteral Nutrition
Metoclopramide Versus Placebo for GJ Placement
The goal of this study is to determine whether use of promotility agents to stimulate gastric peristalsis can reduce fluoroscopy time and procedure time during gastrojejunostomy (GJ) tubes placement in interventional radiology…
- Trial name
- NCT03331965
- Testing
- Metoclopramide 5 MG/ML Injectable Solution, Saline
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Duke University
Akathisia, Nausea
Efficacy and Akathisia Incidence of Slow Infusion Metoclopramide
Study Objective: The purpose of this study is to compare the effects of metoclopramide administration in bolus versus slow infusion medications in ED patients complaining of nausea for the determination of the therapeutic effect…
- Trial name
- NCT01069536
- Testing
- metoclopramide 10 mg
- Volunteers
- 140 people
- Sponsor
- Pamukkale University
Solid Tumors
MEtoclopramide, DExamethasone or Axoli to Prevent or Delay Chemotherapy-induced Nausea and Vomiting in Moderately Emetogenic Non-AC-based Chemotherapy
In this phase III non-inferiority trial, the aim is to evaluate whether metoclopramide and palonosetron prophylactic antemetic treatment are non-inferior to dexamethasone with regard to its efficacy to prevent delayed…
- Trial name
- MEDEA (NCT02135510)
- Testing
- metoclopramide, dexamethason, palonosetron
- Where
- 7 sites in Netherlands
- Volunteers
- 249 people
- Sponsor
- Amsterdam UMC, location VUmc
Diabetic Gastroparesis
Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Men With Diabetic Gastroparesis
The purpose of this study is evaluate the safety and efficacy of Metoclopramide Nasal Spray compared to placebo in reducing the symptoms of diabetic gastroparesis in adult men.
- Trial name
- NCT02025751
- Testing
- Metoclopramide Nasal Spray
- Where
- 49 sites in United States
- Volunteers
- 53 people
- Sponsor
- Evoke Pharma
Primary Headache
Dexamethasone Plus Metoclopramide Versus Paracetamol/NSAIDs for Primary Headache
Primary headache disorders are among the most common neurological conditions presenting to emergency departments and can significantly impair quality of life and daily functioning.
- Trial name
- DMPH (NCT07605065)
- Testing
- Dexamethasone Plus Metoclopramide, Paracetamol/NSAIDs
- Volunteers
- 94 people
- Sponsor
- Pak Emirates Military Hospital
Headache
Metoclopramide Versus Ketorolac for Tension-type Headache
Occasionally, episodic tension-type headache may be severe enough to require an emergency department (ED) visit. The purpose of this study is to compare two commonly used medications to see which is better for tension type…
- Trial name
- NCT01011673
- Testing
- Metoclopramide, Ketorolac
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Montefiore Medical Center