Clinical trials: Mets
Metabolic Syndrome, Type 2 Diabetes
LUPS-Lipids and Glucose Under Prospective Surveillance
Prospective, non-randomized cohort study to analyse genetic variations, dietary patterns, perceived stress and anxiety and early changes in lipid metabolism leading to the metabolic syndrome and type 2 diabetes
- Trial name
- LUPS (NCT01313156)
- Where
- 2 sites in Germany
- Volunteers
- 1,962 people, healthy volunteers welcome
- Sponsor
- Asklepios proresearch
Diabetes Mellitus, Type 2, Metabolic Syndrome
TCM Syndrome Differentiation of T2DM & MetS
This study aims to include type 2 diabetes (T2DM) patients comorbid with metabolic syndrome (MetS). The primary aim of the study is to investigate the TCM (Traditional Chinese Medicine) syndrome differentiation of T2DM comorbid…
- Trial name
- NCT06703684
- Testing
- Cross-sectional observational study
- Where
- Hong Kong
- Volunteers
- 470 people
- Sponsor
- Hong Kong Baptist University
Advanced Cancers (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Mets) With Specific Mutations (Homologous Recombination Deficiency)
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Open label, multi-centre, Phase Ia/b adaptive design study with an initial 2-stage Dose Escalation Phase followed by a Dose Expansion Phase.
- Trial name
- NCT06458712
- Testing
- DSB2455
- Where
- 21 sites in United States, France and 3 more
- Volunteers
- 180 people
- Sponsor
- Duke Street Bio Ltd
Pediatric Obesity, Metabolic Syndrome
Cardio-Metabolic Risk Evaluation in Overweight and Obese Children
Metabolic and cardio-vascular complications can often appear in overweight and obese children from an early age. Currently, there are few studies in the specialized literature that correlate clinical, biological and ultrasound…
- Conditions
- Pediatric Obesity, Metabolic Syndrome, Nonalcoholic Fatty Liver, Atherosclerosis
- Trial name
- CardMetSOb (NCT05908877)
- Testing
- History and Clinical evaluation, Biological evaluation of the metabolic syndrome and components, Ultrasound evaluation of subclinical atherosclerosis and visceral fat storage
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neoped - Centru de Pediatrie
Obesity
Effectiveness of MD on MetS Patients
The metabolic syndrome (MetS), is a complicated condition linked to coronary artery disease.This group includes visceral obesity (abdominal or android type obesity), insulin resistance (IR), hypertension, and dyslipidaemia.The…
- Trial name
- NCT06961682
- Testing
- MD
- Volunteers
- 170 people
- Sponsor
- Assiut University
Metabolic Syndrome, Obesity
Mobile Health (M-health) Intervention to Reduce the Epigenetic Signature in Metabolic Syndrome (MetS)
The goal of this interventional study is to learn about the improvement in body composition effects of lifestyle intervention in subjects with metabolic syndrome.
- Trial name
- NCT06448806
- Testing
- mobile health lifestyle intervention
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Metastatic Melanoma
Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts
Purpose of this Pilot Study: The investigators want to study the safety, side effects, and benefits of tumor infiltrating lymphocytes (TILs), when they are given with the drug ipilimumab.
- Trial name
- NCT01701674
- Testing
- Ipilimumab, Tumor Infiltrating Lymphocytes (TIL), Administration of Lymphodepletion
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Bone Metastases of a Malignant Tumor, Metastatic Bone Tumor
Hemiarthroplasty for Elderly With Proximal Humeral Mets
Bone metastases are common in patients with advanced cancer and frequently involve the proximal humerus, leading to severe pain and loss of shoulder function.
- Trial name
- PHM-HA (NCT07471022)
- Testing
- Proximal Humeral Hemiarthroplasty
- Volunteers
- 53 people
- Sponsor
- Sichuan Provincial People's Hospital
Psoriasis, Psoriatic Arthritis (PsA)
Ten-Year Biologic Drug Survival in Psoriasis: Role of Genetic and Cardiometabolic Predictors
This retrospective observational study aims to evaluate the long-term survival of biologic therapies in adult patients with moderate-to-severe cutaneous psoriasis, with or without psoriatic arthritis, over a period of up to 10…
- Conditions
- Psoriasis, Psoriatic Arthritis (PsA), Cardiovascular Risk Factors, Metabolic Syndrome (MetS)
- Trial name
- GENBIOPSO (NCT07041112)
- Testing
- Biologic therapy for psoriasis
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Juan Ruano Ruiz
Metabolic Syndrome (MetS), Periodontitis
Metabolic Syndrome-Associated Periodontal Inflammatory Surface Area
This study aims to examine the potential of metabolic syndrome (MetS), a systemic, inflammatory disease, to influence the relationship between periodontal inflammatory surface area (PISA) and diabetes and obesity parameters.
- Trial name
- NCT07354815
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Healthy
Energy Expenditure in Golf
Structured exercise and physical activity are well known to not only improve physical fitness, but also alter various health parameters in a positive fashion.
- Trial name
- NCT04496323
- Testing
- EE Golf
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Neoplasms, Unknown Primary
Cost-effectiveness Study of miRview™ Mets in Patients With Cancer of Unknown Primary (CUP)
The aim of the study is in cancer of unknown primary (CUP) patients, to compare the cost-effectiveness of miRview™ mets test with conventional work-up in identifying the primary tumor site.
- Trial name
- NCT01202786
- Where
- 3 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Bone Metastases, Breast Cancer
Pilot, Syndros, Decreasing Use of Opioids in Breast Cancer Subjects With Bone Mets
In patients with cancer induced bone pain, addition of Syndros will improve pain relief and decrease opioid requirement.
- Conditions
- Bone Metastases, Breast Cancer, Pain
- Trial name
- NCT03661892
- Testing
- Syndros
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Arizona
Mets
Application of Decision Analysis Techniques' in Huge Health-checkup Database to Explore the High-risk Group With Metabolic Syndrome
Application of Decision Analysis Techniques' in Huge Health-checkup Database to Explore the High-risk Group With Metabolic Syndrome (MetS)
- Trial name
- NCT04142593
- Where
- Taiwan
- Volunteers
- 100,000 people
- Sponsor
- Far Eastern Memorial Hospital
Liver Metastases
Stereotactic Body Radiation Therapy (SBRT) for Liver Mets
This is a phase I dose escalation study. Dose escalation will be via the traditional "up and down" scheme. SBRT: Patients will receive one of the following radiation regimens: 50 Gy in 5 fractions (10 Gy/fx) delivered over a…
- Trial name
- NCT01360606
- Testing
- Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Susannah Ellsworth