Clinical trials: Microalbuminuria
Diabetic Nephropathy Type 2, Microalbuminuria Due to Type 2 Diabetes Mellitus
Efficacy of ACE Inhibitors, MRAs and ACE Inhibitor/ MRA Combination
The aim of our work is to compare the antiproteinuric efficacy of ACEI monotherapy, Selective MRA monotherapy and their combination in mildly hypertensive patients with type 2 diabetes mellitus and microalbuminuria
- Trial name
- NCT04143412
- Testing
- Tritace (Ramipril 10 mg)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Beni-Suef University
Hypertension, Diabetes Mellitus, Type 2
Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects
New strategies trying to achieve blood pressure control and consequently reduce cardiovascular risk in resistant hypertensive subjects are promising.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Blood Pressure, Obesity
- Trial name
- NCT03089333
- Testing
- Dapagliflozin 10mg, Glibenclamide 5Mg Tablet
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- University of Campinas, Brazil
Hypertension, Type 2 Diabetes Mellitus
Amiloride for Resistant Hypertension
To evaluate the antihypertensive effect of amiloride added to triple antihypertensive therapy in patients with resistant hypertension (RH) and type 2 diabetes mellitus (T2DM)
- Conditions
- Hypertension, Type 2 Diabetes Mellitus, Microalbuminuria
- Trial name
- NCT02122731
- Testing
- Amiloride
- Where
- 4 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Ib Abildgaard Jacobsen
Inflammation
Analysis of Microalbuminuria and Markers of Inflammation and Oxidative Stress in Adolescents of Different Ethnic Backgrounds
The purpose of this study is to determine if there are signs of inflammation in one's blood and urine and to find out if one's body size or ethnicity has an effect on these substances.
- Trial name
- IM (NCT00616707)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, Davis
Kidney Function Affection Upon Exposure to Radiocontrast, Diabetes
Contrast Nephropathy in Type 2 Diabetes
To study the effect of radiocontrast material on kidney functions in diabetics with microalbuminuria
- Conditions
- Kidney Function Affection Upon Exposure to Radiocontrast, Diabetes, Microalbuminuria
- Trial name
- VCG4 (NCT03470454)
- Testing
- Linagliptin Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Diabetic Nephropathy
A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Type 2 Diabetic Subjects With Microalbuminuria
This study is a randomized, placebo-controlled, double-blind, multi-center study to evaluate efficacy and safety of different doses of CS-3150 compared to placebo in Japanese Type 2 Diabetes Mellitus and Microalbuminuria.
- Trial name
- NCT02345057
- Testing
- CS-3150
- Where
- Japan
- Volunteers
- 365 people
- Sponsor
- Daiichi Sankyo
Hypertension, Type 2 Diabetes
Higher Dose of Ramipril Versus Addition of Telmisartan-Ramipril in Hypertension and Diabetes
The purpose of this study is to determine if a dose of ramipril combined with a normal dose of telmisartan 80 mg will be more effective than ramipril 20 mg in reducing microalbuminuria in hypertensive patients with diabetes.
- Conditions
- Hypertension, Type 2 Diabetes, Albuminuria
- Trial name
- NCT00208221
- Testing
- ramipril, ramipril-telmisartan
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Diabetes Mellitus, Microalbuminuria
Aspirin and Enalapril in Microalbuminuric Type 2 Diabetes Mellitus Patients
Research design: randomized, double-blind, placebo-controlled crossover study to evaluate the putative interference of low-dose aspirin (for 8 weeks) on enalapril antiproteinuric properties in microalbuminuric type 2 diabetes…
- Trial name
- NCT00427271
- Testing
- aspirin
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Corticosteroids Adverse Reaction
Arrhythmias, Microalbuminuria and Corticosteroids
The goal of this observational design is to study the effects of intravenous corticosteroids on heart rate variability, arrhythmias and microalbuminuria.
- Trial name
- NCT03453931
- Testing
- Corticosteroid injection
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Elza Abdessater
Chronic Kidney Diseases
Home-Based Kidney Care in Native American's of New Mexico (HBKC)
People reach End Stage Renal Disease (ESRD) due to progressive chronic kidney disease (CKD). CKD is associated with increased risk for heart disease and death.
- Trial name
- NCT03179085
- Testing
- Home-Based Kidney Care
- Where
- United States
- Volunteers
- 529 people
- Sponsor
- University of New Mexico
Hypertensive Nephropathy, Auto Immune Disorders
ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases
This study investigates the safety and efficacy of ACE Reno, an oral transmucosal solution containing standardized bioactive peptides and amino acids, in patients with nephropathy of various etiologies and stages.
- Conditions
- Hypertensive Nephropathy, Auto Immune Disorders, Chronic Kidney Disease, Chronc Kidney Disease Stage 5
- Trial name
- ACE Reno (NCT07187713)
- Testing
- ACE Reno
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ace Cells Lab Limited
Diabetes, Microalbuminuria
Perindopril vs Ramipril for Persistence in MAU Reduction Study
The investigators conducted a single center study controlled study involving 20 patients with Type 2 Diabetes and hypertension who were randomly assigned to receive ramipril 10mg or perindopril 8mg.
- Trial name
- ENDURE (NCT02729441)
- Testing
- ramipril, perindopril
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetic Nephropathy
To Determine the Efficacy and Safety of DW1029M on Microalbuminuria in Patients With Diabetic Nephropathy
Phase 2 clinical study to evaluate of the efficacy and safety of DW1029M on microalbuminuria in Patients With Diabetic Nephropathy
- Trial name
- NCT01935167
- Testing
- DW1029M 600mg, DW1029M 1200mg
- Where
- South Korea
- Volunteers
- 158 people
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Microalbuminuria, Diabetic Nephropathy
Chicken-Diet vs. Enalapril to Reduce Albuminuria
Diabetic nephropathy (DN) is a chronic diabetic complication and affects up to 40% of patients. The first line treatment for DN is angiotensin blockers drugs that are used to reduce the protein concentration in urine.Previous…
- Trial name
- NCT00484068
- Testing
- enalapril, chicken diet
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Microalbuminuria, Sickle Cell Nephropathy
Efficacy of Antioxidant Therapy Compared With Enalapril in Sickle Nephropathy
The purpose of this study is to determine whether enalapril or antioxidant therapy (N-Acetylcysteine) is effective in reducing microalbuminuria in children with sickle cell disease and and its progression to sickle nephropathy
- Trial name
- NCT01891292
- Testing
- Enalapril, N-Acetylcysteine
- Where
- Jamaica
- Volunteers
- 30 people
- Sponsor
- The University of The West Indies
Hypertension
Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With Hypertension
To explore the efficacy of Sacubitril/Valsartan in the treatment of perimenopausal hypertensive patients, as well as the difference between the antihypertensive efficacy and valsartan, the therapeutic effect of its exposure to…
- Trial name
- NCT04800081
- Testing
- Sacubitril/Valsartan, Valsartan
- Where
- China
- Volunteers
- 264 people
- Sponsor
- LanZhou University
Hypertension
VALERIA: Valsartan in Combination With Lisinopril in Hypertensive Patients With Microalbuminuria
The purpose of this study is to compare if the combination of valsartan 320 mg/lisinopril 20 mg versus the monotherapies of lisinopril 40 mg or valsartan 320 mg will result in a greater decrease of urinary albumin excretion…
- Trial name
- NCT00171067
- Testing
- valsartan, lisinopril
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 134 people
- Sponsor
- Novartis
Hypertension, Diabetes Mellitus, Type 2
ADDM Study - Amtrel and Co-Diovan in Type 2 Diabetes Mellitus Hypertension Patients With Microalbuminuria
The purpose of the study is to compare the change from baseline in blood pressures (DBP/SBP) to 16-week regimen between Amtrel® and Co-Diovan®. The secondary objectives were listed as the following.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Albuminuria
- Trial name
- NCT01375322
- Testing
- Amlodipine+Benazepril, Valsartan+Hydrochlorothiazide
- Where
- 4 sites in Taiwan
- Volunteers
- 226 people
- Sponsor
- TSH Biopharm Corporation Limited
HIV
Does Micro-albuminuria is a Predictive Factor for Cognitive Impairment in Persons Living With HIV (PLHIV) Who Achieve cART-sustained Immunovirological Control ?
Chronic kidney disease (CKD), frequent in PLHIV, is a risk factor for cognitive impairment. Micro-albuminuria is an early manifestation of CKD and a marker of vascular risk, notably affecting the small vessels.
- Trial name
- ALCOVE (NCT02852772)
- Testing
- Cognitive function tests
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild