Clinical trials: Microperimetry
Retinal Detachment
DOREFA (Retinal Detachment: Function and Anatomy)
Patients with retinal detachment do not always recover good visual function. Sometimes simple causes are responsible. Other causes can only be discovered thanks to high-resolution imaging provided by the latest generation of OCT.
- Trial name
- DOREFA (NCT01767038)
- Testing
- OCT Spectralis, microperimetry
- Where
- 10 sites in France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Retinal Detachment, Vitrectomy
Functional and Morphological Results of Rhegmatogenous Retinal Detachment Treated With Vitrectomy
To examine morphological and functional results after pars plana vitrectomy (PPV) with SF6 gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during six months of the follow-up.
- Trial name
- NCT03902795
- Testing
- Microperimetry, M-charts
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Lublin
Neovascular Age Related Macular Degeneration
Study Investigating OCT, Multifocal ERG, and Microperimetry in Monthly Versus PRN Ranibizumab in Neovascular Age-Related Macular Degeneration
Visual outcomes using monthly ranibizumab therapy are well established in clinical trials, but the best way to assess when and how to treat patients with PRN therapy has not been proven.
- Trial name
- NCT00764738
- Testing
- OCT, Multifocal ERG, Microperimetry, Ranibizumab Ophthalmic
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Retina Macula Institute
Epiretinal Membrane
Microperimetry and Optical Coherence Tomography (OCT) in Idiopathic Epiretinal Membrane
Purpose: To evaluate macular sensitivity and its correlation with visual acuity and Spectral Domain Optical Coherence Tomography (SD-OCT) in eyes with idiopathic epiretinal membrane (ERM).
- Trial name
- NCT01481987
- Testing
- Epiretinal Membrane Surgical treatment
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Macular Holes
The Use of Amniotic Membrane or Internal Limiting Membrane for Large or Refractory Macular Holes: A Prospective Study
Prospective, randomized, unmasked interventional study. To evaluate anatomical and functional results through microperimetry in cases of refractory or large macular holes (MH), using amniotic membrane (AM) or internal limiting…
- Trial name
- NCT04904679
- Testing
- Pars plana Vitrectomy with internal limiting membrane peeling
- Where
- 2 sites in Brazil
- Volunteers
- 23 people
- Sponsor
- Hospital Oftalmologico de Sorocaba
Age-related Macular Degeneration
Global Atrophie Biomarker Evaluation Study (GABiE)
To investigate the use of microperimetry and SS-OCT in assessing the natural changes of retinal sensitivity and anatomy in the perilesional zone of geographic atrophy areas in patients with dry age-related macular degeneration.
- Trial name
- GABiE (NCT03935126)
- Testing
- Diagnostics
- Where
- 2 sites in United States, Switzerland
- Volunteers
- 3 people
- Sponsor
- Boehringer Ingelheim
Retina; Change
Adaptation Time Required for the Optimisation of Maia Microperimetry Visual Field Testing
Microperimetry is a relatively new and extremely sensitive method of assessing visual function. It projects light stimuli onto a defined area of the retina to map retinal perceptual thresholds.
- Trial name
- NCT02729818
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Glaucoma
Photographic Imaging of the Retina and Optic Nerve Head of Glaucoma Patients and Normal Controls
Retinal structures are difficult to visualize because the retina is optically transparent. In glaucoma, the microglia in the retina becomes activated in eyes with glaucomatous damage.
- Trial name
- NCT00430274
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Selim Orguel
Macular Hole
Microperimetry and Optical Coherence Tomography (OCT) in Idiopathic Macular Hole
To evaluate the correlations between anatomical and functional changes studied with microperimetry (MPM) and spectral-domain OCT (SD-OCT) in patients after successful repair of idiopathic macular hole (MH).
- Trial name
- NCT01757600
- Testing
- Microperimetry
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Age-related Macular Degeneration (AMD)
Measuring Geographic Atrophy in AMD Patients Using the Nidek MP-3 Microperimetry Device
The investigators would like to know if different imaging devices can improve the quality of images and visualization of imaged tissues.
- Trial name
- NCT02445313
- Testing
- Nidek MP-3
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Doheny Image Reading Center
Branch Retinal Vein Occlusion, Macular Edema
Navigated Laser In Branch Retinal Vein Occlusion Study
Branch retinal vein occlusion (BRVO) is often complicated by macular edema, possibly leading to severe visual loss or blindness.
- Trial name
- NIRVANA (NCT03651011)
- Testing
- Aflibercept Injection [Eylea], Navigated laser photocoagulation
- Where
- 2 sites in Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Retinitis Pigmentosa, AMD
Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)
A new fundus-guided microperimeter (MP-3S) has been developed by Nidek, Inc. to track the fundus of the patient and present stimuli in specific anatomically-defined locations.
- Trial name
- NCT03322930
- Testing
- Rod sensitivity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Retina Foundation of the Southwest
Age-Related Macular Degeneration, Geographic Atrophy
Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO
To conduct a precision study to assess the microperimetry function of the Spectral OCT/SLO. The study will assess variability across measurements taken by three different operator-device configuration across clinical sites…
- Conditions
- Age-Related Macular Degeneration, Geographic Atrophy, Diabetic Retinopathy, Macular Edema
- Trial name
- NCT01692938
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Retinal Function, Cognitive Dysfunction
Retinal and Cognitive Dysfunction in Type 2 Diabetes
The retina shares similar embryologic origin, anatomical features and physiological properties with the brain and hence offers a unique and accessible "window" to study the correlates and consequences of subclinical pathology in…
- Conditions
- Retinal Function, Cognitive Dysfunction, Microperimetry
- Trial name
- RECOGNISED (NCT04281186)
- Where
- Spain
- Volunteers
- 510 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Macular Edema, Uveitis
Microperimetry in Macular Edema
In uveitic patients with fluorescein angiographically proven macular edema, a fundus related microperimetry is performed and results are correlated with foveal thickness as measured with optical coherence tomography (OCT).
- Trial name
- NCT00791726
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- St. Franziskus Hospital