Clinical trials: Microplastics
Environmental-Pollution-Related Condition
Microplastica Pollution Awareness Level of Students
This study aims to raise awareness among individuals about plastic and microplastica pollution, reduce plastic consumption, reduce the amount of plastic waste that grows cumulatively every year, and contribute to the development…
- Trial name
- NCT06127862
- Testing
- Education group, No training was given
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Firat University
Female Infertility, Environmental Exposure
Detection of Microplastics in Human Granulosa Cells and in the Follicular Fluid of Women Undergoing ICSI Treatment
Plastic products have been used ubiquitously in the modern world for many decades - for example as packaging materials, textile fibers or molded parts.
- Trial name
- MP2021 (NCT05179993)
- Testing
- Microplastics
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Crohn Disease, Pediatric Inflammatory Bowel Diseases
Microplastic Analysis in Pediatric Inflammatory Bowel Disease
The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD.
- Conditions
- Crohn Disease, Pediatric Inflammatory Bowel Diseases, Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- MAP-IBD (NCT07141238)
- Testing
- Environmental microplastic exposure
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Obesity and Overweight
Identification of Microplastics in Liver, Stomach, Blood, and Feces of Obese Patients and Their Association Analysis with Macrogenomics and Metabolomics.
The aim of this study was to identify and quantify microplastics in the stomach, liver, feces, and blood of obese patients to be treated with bariatric surgery by using a variety of advanced analytical techniques to explore the…
- Trial name
- NCT06826586
- Testing
- Measuring the microplastics
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Chronic Kidney Diseases, Microplastics
Biomonitoring of Internal Exposure to MNPLs, and Its Effects, in Blood of Patients With Chronic Kidney Disease (CKD)
Micro and nanoplastics (MNPLs) effects on human heath is still preliminary. Chronic kidney disease (CKD) participants, specially does patients submitted to hemodialysis, are a population high exposed to plastics.
- Conditions
- Chronic Kidney Diseases, Microplastics, Nanoplastics, Genotoxic Damage
- Trial name
- NCT05155267
- Testing
- Biomonitoring study to detect MNPLs in biological samples and study of their health effects
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ricard Marcos
Bronchopulmonary Dysplasia
Preliminary Study on Microplastics Deposition in Ventilator Circuit and the Risk of Bronchopulmonary Dysplasia in Premature Infants
In this study, the premature infants with gestational age less than 30 weeks were taken as the object, and the deposition characteristics of microplastics in ventilator circuit and its correlation with the risk of…
- Trial name
- Microplastics (NCT07848646)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiyi Li
Microplastics, Lung Cancer (NSCLC)
Microplastics in the Human Respiratory System
Environmental pollution from plastics has become a significant global issue, with microplastics-tiny particles resulting from plastic degradation-being increasingly detected in various environments, including aquatic ecosystems…
- Conditions
- Microplastics, Lung Cancer (NSCLC), Lung Transplantation
- Trial name
- NCT06603675
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Cirrhosis, Microplastics
Microplastics, Cirrhosis and Portal Hypertension
Cirrhosis and portal hypertension are associated with an hyperdynamic circulation and hepatic inflammation, leading to complications like ascites, variceal bleeding, acute kidney injury, and higher infection risk.
- Conditions
- Cirrhosis, Microplastics, Portal Hypertension Related to Cirrhosis, Nanoplastics
- Trial name
- NCT07280390
- Testing
- Assessment of microplastics in tissue
- Where
- 2 sites in India
- Volunteers
- 30 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Osteoarthritis, Knee, Knee Arthritis
Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid
The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes.
- Conditions
- Osteoarthritis, Knee, Knee Arthritis, Gout Arthritis, Microcrystal Disease
- Trial name
- NCT05678049
- Testing
- Synovial fluid analysis
- Volunteers
- 50 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Microplastics, Nanoplastics
Micro and Nanoplastics in Greenhouse Workers: Biomarkers of Exposure and Effect
MNPLs effects on human health are still preliminary. Workers exposed to plastic residues are exposed constantly to MNPLs. One of these jobs corresponds to greenhouse workers, that could be considered as a population highly…
- Conditions
- Microplastics, Nanoplastics, Genotoxic Damage, Inflammation
- Trial name
- NCT05910489
- Testing
- Biomonitoring of MNPLs in biological samples of greenhouse workers and controls
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ricard Marcos
Lung Cancer
Investigation of MP Pollution in the Human Respiratory System and Its Relationship to Lung Cancer
This project will study and characterize Microplastic (MP) burden in the lungs of patients undergoing Bronchoalveolar Levage (BAL) in thoracic clinics at Moffitt.
- Trial name
- NCT06530615
- Testing
- Bronchoalveolar Lavage (BAL) during Bronchoscopy
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Atopic Dermatitis
Prenatal Exposure to Emerging Contaminants and Children's Atopic Dermatitis
This prospective cohort study aims to investigate the association between prenatal blood levels of Emerging Contaminants and the five-year incidence of atopic dermatitis (AD) in offspring.
- Trial name
- PECCAD (NCT06316609)
- Testing
- Gestational Exposure to Emerging Contaminants (ECs)
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Children's Hospital of Fudan University
Pancreatic Diseases, Pancreatic Neoplasms
Microplastics in Pancreas: Oncologic and Metabolic Impact
Microplastics and nanoplastics (MNPs) are emerging environmental contaminants that have been detected in several human tissues, raising concerns about their potential impact on human health.
- Trial name
- PAN-Plastic (NCT07486128)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Microplastics, Otitis Media With Effusion
Microplastics in Otitis Media With Effusion Material
Microplastic rate is increasing ib athmosphere. They can be found in lung, kidney, heart, even placenta. Otitis media with effusion (OME) is a clinical condition that is ver common in children.
- Conditions
- Microplastics, Otitis Media With Effusion, Biofilms
- Trial name
- NCT06316635
- Testing
- ventilation tube insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kerem Kökoğlu
Infant Development, Breast Feeding
Developmental Impacts of Microplastics Exposure in Early Life
The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothers and infants in mother-infant dyads 1 or 3 months postpartum living in Baltimore, Maryland.
- Conditions
- Infant Development, Breast Feeding, Environmental Exposure
- Trial name
- DIMPLE (NCT06107933)
- Testing
- Observational only
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Microplastic Exposure
Microplastic Exposure From Clear Aligner Wear (MPE)
An observational longitudinal study measuring microplastic exposure and physiologic uptake in orthodontic patients receiving clear aligner treatment.
- Trial name
- MPE (NCT06934603)
- Testing
- Clear Aligner Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill
Periodontal Diseases, Periodontitis
Detection of Microplastics in Patients With Periodontitis
Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system.
- Trial name
- micropl_perio (NCT07231198)
- Volunteers
- 25 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Crohns Disease, Pregnancy
Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation
The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as…
- Conditions
- Crohns Disease, Pregnancy, Inflammatory Bowel Disease
- Trial name
- PLANET (NCT06001450)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gastric Carcinoma, Gastritis Chronic
Association Between Microplastic Exposure and the Pathological Progression of Gastric Carcinogenesis
The objective of this clinical trial is to explore the correlation between the level of microplastic exposure and the risk of gastric mucosal carcinogenesis, and to evaluate the strength of its effect as an independent risk…
- Conditions
- Gastric Carcinoma, Gastritis Chronic, Intestinal Metaplasia, Gastric Precancerous Lesions
- Trial name
- NCT07542652
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Yongquan Shi
Healthy Adult Participants
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
The goal of this observational study is to evaluate the feasibility and usability of at-home urine sample collection, preparation, and smartphone imaging using the EcoExposure™ platform in adults.
- Trial name
- OMNU (NCT07775495)
- Where
- 51 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ecotera Health LLC