Clinical trials: Midazolam Premedication
Emergence Delirium
Intranasal Dexmedetomidine Versus Intranasal Midazolam for Emergence Delirium Prevention
This study is a double-blind clinical trial, in pediatric patients aged 1-12 years with physical status ASA (American Society of Anesthesiology) 1 and 2 who underwent eye surgery under general anesthesia using Sevoflurane…
- Trial name
- NCT04263844
- Testing
- Intranasal dexmedetomidine, Intranasal Midazolam
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Universitas Indonesia
Early Gastric Cancer, Gastric Adenoma
Effect of Midazolam Premedication on the Satisfaction Levels of Patients After Endoscopic Submucosal Dissection
Endoscopic submucosal dissection is commonly performed under light to moderate sedation, and minimizing patient movement is of key importance for successful outcome.
- Trial name
- NCT02504164
- Testing
- midazolam 0.02mg/kg, No premedication
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Emergence Delirium, Anesthesia, Child
Melatonin vs Midazolam in Children Undergoing Tonsillectomy
Used as a premedication to decrease anxiety (Caumo et al., 2007). Midazolam, though has several drawbacks (McCann and Kain, 2001). Hence, an alternative premedication to midazolam will definitely have a widespread appeal.
- Conditions
- Emergence Delirium, Anesthesia, Child, Anxiety, Midazolam Premedication
- Trial name
- NCT07336095
- Testing
- Melatonin group, Midazolam group, Control group
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Emergence Delirium
Effect of Ketamine/Midazolam Premedication Versus Pre-extubation Ketofol on Recovery Profile in Pediatrics Undergoing Adenotonsillectomy.
An optimum recovery profile after AT includes a rapid, smooth awakening without emergence agitation (EA), stable vital signs and oxygenation, reduced postoperative nausea and vomiting (PONV), controlled postoperative pain, and…
- Trial name
- NCT06010927
- Testing
- ketamine/midazolam, Ketofol
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Ketamine Induced Agitation
Reducing Ketamine-Induced Agitation, by Midazolam or Haloperidol Premedication After Adult Procedural Sedation
Ketamine is the cornerstone of procedural sedation in emergency department but ketamine induced agitation has limited its usage by many physicians.
- Trial name
- NCT02909465
- Testing
- Midazolam, Haloperidol, Ketamine
- Where
- Iran
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Tonsillectomy, Adenoidectomy
Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events
The aim of this study is to investigate the effect of addition of intranasal ketamine to midazolam compared to midazolam alone as a premedication on the occurrence of PRAEs
- Conditions
- Tonsillectomy, Adenoidectomy, Drug-Related Side Effects and Adverse Reaction
- Trial name
- NCT06122948
- Testing
- The midazolam group, The midazolam ketamine group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Behavior Problem
Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children
The goal of this clinical trial is to learn the effect of dexmedetomidine premedication in postoperative negative behavior changes in children compared to midazolam premedication.
- Trial name
- NCT06417125
- Testing
- Dexmedetomidine Hydrochloride, Midazolam, normal Saline
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Fujian Provincial Hospital
Anxiety
Combination With Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Patients
Children tend to anxiety and even fear before survey. And this kind of anxiety will not result in the forced induction of anesthesia, but also may increase the incidence of postoperative agitation in children, even lead to…
- Trial name
- NCT04135014
- Testing
- Midazolam, Dexmedetomidine, Midazolam and Dexmedetomidine
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Inhalational Anesthetics Adverse Reaction, Delirium on Emergence
Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children
Sevoflurane is frequently used for pediatric anesthesia because it has low pungency and rapid onset and offset of action.The reported incidence of emergence agitation (EA) following sevoflurane anesthesia varies from 10-80%.
- Conditions
- Inhalational Anesthetics Adverse Reaction, Delirium on Emergence, Strabismus Following Ocular Surgery
- Trial name
- NCT01895023
- Testing
- Dexmedetomidine, Midazolam, Saline
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Yao Yusheng
Hypertension
Dexmedetomidine Premedication in Hypertensive Patients
Hypertensive patients' often severe hypotensive response after induction of anesthesia and excessive increase in blood pressure to stresses such as laryngoscopy, intubation, surgical incision and extubation.
- Trial name
- NCT02058485
- Testing
- Midazolam, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Duzce University
Chronic Disease
Premedication for ERCP With Midazolam or Tramadol
OBJECTIVE:Purpose of this study is to set forth the sedative efficacy and effects on early period cognitive functions of two premedication drugs used for ERCP (Endoscopic retrograde cholangiopancreatography) METHODS:This…
- Trial name
- NCT02436980
- Testing
- Tramadol, Midazolam
- Volunteers
- 40 people
- Sponsor
- Karadeniz Technical University
Autism Spectrum Disorder, Premedication
EMERGENCE AGITATION After Premedication IN PAEDIATRIC MAGNETIC RESONANCE IMAGING: A RETROSPECTIVE COHORT STUDY
The aim of this study was to assess the anxiolytic and sedative effect of OZALIN® / OZASED® (ADV6209) 0,25mg/Kg in children undergoing magnetic resonance imaging (MRI) under inhalational anesthesia.
- Conditions
- Autism Spectrum Disorder, Premedication, Brain Neoplasms, Brain Pathology
- Trial name
- premidazolam (NCT05946928)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anxiety
Interactive Tablet Compared to Oral Midazolam as Premedication in Preoperative Anxiety in Children
preoperative anxiety is an undesirable outcome in pediatric surgical patients.It can lead to behavioral trouble such as enuresis, apathy and sleep disorders.
- Trial name
- NCT04049201
- Testing
- elective surgery, Midazolam, Interactive Tablet
- Where
- Tunisia
- Volunteers
- 112 people
- Sponsor
- Hôpital d'enfants Béchir-Hamza
Anxiety, Pain
Clonidine Versus Midazolam for Premedication
alpha2-agonists like clonidine offer several useful effects that make these drugs an interesting alternative to benzodiazepines for pharmacological premedication.
- Trial name
- NCT00638729
- Testing
- midazolam, clonidine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Preoperative Sedation
Nebulized vs. Oral Midazolam Sedation in Pediatric Anesthesia: A Randomized Comparative Study
This study is to be carried out to compare nebulized and oral midazolam in achievement of a satisfactory level of sedation, Ramsey Sedation Score (RSS) of 4, within 30 mins of midazolam administration in pediatrics.
- Trial name
- NCT04760041
- Testing
- Midazolam nebulized, Midazolam oral solution
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cairo University
Strabismus, Reflex, Oculocardiac
Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Oculocardiac reflex (OCR) is usually happening in pediatric strabismus surgery and observed just when the surgent pulls the ocular muscles.
- Conditions
- Strabismus, Reflex, Oculocardiac, Hydroxyzine, Bradycardia Sinus
- Trial name
- NCT03806270
- Testing
- Midazolam, Hydroxyzine Dihydrochloride
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Yeditepe University
Propofol, Anesthesia Brain Monitoring
Effect of Midazolam Bolus on Eleveld and Schnider TCI (Target Controlled Infusion) Models
No trials have evaluated the effect of a Midazolam bolus (routinely used for premedication before general anesthesia) on the Concnetration at the effector site of Propofol (CeP) of Eleveld and Schnider TCI models, routinely used…
- Trial name
- TCI (NCT05800288)
- Testing
- Propofol
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova