Clinical trials: Middle Aged Patients
Type 2 Diabetes Mellitus (T2DM)
Effects of a Multimodal Exercise Program on Physical Performance and Muscle Function in Middle-aged Patients With T2DM
Background Middle-aged adults with type 2 diabetes mellitus (T2DM), especially in Asian populations, are at increased risk of sarcopenia, reduced muscle function, and decline in physical performance.
- Trial name
- NCT07255222
- Testing
- A Multimodal Exercise Intervention
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Chung Shan Medical University
Patient Admission, Death
Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study
Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain.
- Conditions
- Patient Admission, Death, Activities of Daily Living
- Trial name
- IceCub (NCT00912600)
- Testing
- Intensive Care Unit admission
- Where
- France
- Volunteers
- 2,643 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension
A Study to Evaluate Methodologies for Measuring Swelling of the Leg and Ankle (MK-0000-106)(COMPLETED)
This study will evaluate methodologies for measuring pedal edema associated with calcium channel blockers in middle-aged and elderly subjects and patients with hypertension.
- Trial name
- NCT00789321
- Testing
- Comparator: amlodipine besylate
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Bipolar II Disorder
add-on Low Dose Memantine in Middle-to-old Aged Bipolar II Disorder Patients
The investigators hypothesized that add-on memantine (MM) 5 mg/day may reduce chronic inflammation, and subsequently improve neuro-progression process and cognitive function in middle-to-old aged bipolar II disorder (BP-II)…
- Trial name
- NCT04035798
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Breast Neoplasms, Breast Self-Examination
Health Belief Model-Based Survey on Breast Self-Examination Awareness and Practice Among Community-Dwelling Middle-Aged and Older Women
This observational study aims to evaluate the current status of breast self-examination (BSE) practices and related influencing factors among middle-aged and older women in urban communities, using the Health Belief Model (HBM)…
- Conditions
- Breast Neoplasms, Breast Self-Examination, Cancer Screening, Health Belief Model
- Trial name
- HBM-BSE (NCT07149636)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Psoriasis
A 36-Week Extension to Protocol ISA04-03
The purpose of this study is to determine the safety and efficacy of voclosporin in patients with plaque psoriasis.
- Trial name
- SPIRIT (NCT00258713)
- Testing
- voclosporin
- Where
- 29 sites in Canada
- Volunteers
- 309 people
- Sponsor
- Aurinia Pharmaceuticals Inc.
Sedation, ED50
Median Effective Dose of Ciprofol-Assisted Sedation for Elderly Patients Undergoing Knee Arthroplasty
Regional anesthesia is a common clinical anesthesia method, and regional anesthesia-assisted sedation play a central role in promoting patient comfort and relieving anxiety.
- Conditions
- Sedation, ED50, Knee Arthroplasty
- Trial name
- NCT06293131
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Hospital of Shanxi Medical University
Geriatric Patients, Efficacy, Self
Median and Paramedian Approach in Spinal Anesthesia
Spinal anesthesia (SA) is frequently used as anesthesia in many surgeries such as lower abdominal, inguinal, urogenital, rectal and lower extremities.
- Trial name
- NCT03750877
- Testing
- median approach, paramedian approach
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Caries,Dental, Caries Root
Coronal and Radicular Caries Prevalence and Related Risk Factor in Diabetic Patient
This study aims to investigate the prevalence and risk factors of coronal and radicular caries in middle-aged individuals with Type 2 diabetes.
- Conditions
- Caries,Dental, Caries Root, Diabetes Mellitus, Type 2
- Trial name
- NCT06701565
- Volunteers
- 265 people
- Sponsor
- Cairo University
Diabetes Mellitus
Effects of Shared Medical Appointments for Diabetic Patients in Taiwan
This quasi-experimental study is done to investigate the effect of Shared Medical Appointments (SMA) program for the diabetic patients in Taiwan.
- Trial name
- NCT06032429
- Testing
- Shared Medical Appointments
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Dalin Tzu Chi General Hospital
Traumatic Injury
Ketogenic Feeding for Muscle Preservation After Trauma
The purpose of this study is to determine whether a ketogenic diet, provided as tube feeding, compared with a standard hospital tube feeding, is safe and feasible and helps preserve muscle mass and improve metabolic health in…
- Trial name
- KETO TRAUMA (NCT07827820)
- Testing
- Ketogenic feeding, Standard feeding
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Knee Pain
Rehabilitation After Arthroscopic Partial Meniscectomy
Water-Based vs. Land-Based Rehabilitation After Arthroscopic Partial Meniscectomy in Middle-Aged Active Patients with a Degenerative Meniscal Tear: A Randomized, Controlled Study
- Trial name
- NCT04925726
- Testing
- Land based exercise, Water based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hilal Yeşil
Chronic Coronary Syndrome
Effect of Intensive Lipid-Lowering Therapy on Coronary Atherosclerotic Plaque Progression in Young and Middle-Aged Patients With Chronic Coronary Syndrome
This is a multicenter, open-label, parallel-group, randomized trial to determine if intensive lipid-lowering therapy (goal for LDL-C <1.0 mmol/L and ≥50% reduction frome baseline) could delay progression of coronary…
- Trial name
- CAPITAL-PLAQUE (NCT06896708)
- Testing
- Intensive lipid-lowering strategy, Standard lipid-lowering strategy
- Where
- 7 sites in China
- Volunteers
- 766 people
- Sponsor
- Liu yong
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Glucose Metabolism Disorders, Lipid Metabolism Disorders
Metabolic Complications Following Knee Injury in Young and Middle Aged Patients
Introduction This study evaluates the effect on glucose, lipid and bone metabolism following knee orthopedic procedures in healthy and physically active individuals.
- Conditions
- Glucose Metabolism Disorders, Lipid Metabolism Disorders, Sedentary Lifestyle
- Trial name
- OrthoMetKnee (NCT02573662)
- Testing
- Blood and Urine sampling, DXA scan, OGTT
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Haugaard, Steen Bendix, M.D., DMSc
Type2 Diabetes Mellitus
The Effects of Short Message Notifications on Middle-Aged Diabetic Patients
The objective of our study was to assess awareness-raising of medication adherence (MA), physical activity (PA), fasting blood glucose (FBG), and glycated hemoglobin A (HbA1c) values by providing information on diabetes via short…
- Trial name
- NCT04733612
- Testing
- Informative messages
- Volunteers
- 125 people
- Sponsor
- Istanbul University
Dental Caries, Caries,Dental
Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University
Dental caries, a widespread oral health issue, results from a complex interplay of factors including behavior, hygiene, diet, and socio-demographic aspects.
- Trial name
- NCT06365281
- Where
- Egypt
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Degenerative Meniscus Tear
The Benefit of Arthroscopic Partial Meniscectomy in Middle-Aged Patients
BACKGROUND Osteoarthritis (OA) is the most common form of arthritis and the knee is one of the most affected joints. The meniscus plays an important role in the development of knee OA.
- Trial name
- SLAMSHAM (NCT01264991)
- Testing
- Arthroscopic partial meniscectomy
- Where
- 2 sites in Denmark
- Volunteers
- 41 people
- Sponsor
- Slagelse Hospital
Hypertension
Promoting Medication Adherence Among Older Adults With Hypertension
Over 70% of US adults 65 or older are diagnosed with hypertension, the leading cause of cardiovascular disease and premature deaths in the world.
- Trial name
- NCT02846220
- Testing
- Overcoming Immunity to Change health coaching
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Tulane University School of Medicine
Quality of Life
Mid-term Survival and Quality of Life of Elderly Patients Undergoing Open Heart Surgery
The purposes of the investigators study is to examine the overall survival and quality of life in elderly patients (> 75 years) undergoing open heart surgery at Hadassah medical center between 2008-2011.
- Trial name
- NCT01654900
- Testing
- No intervention in this study
- Where
- Israel
- Volunteers
- 207 people
- Sponsor
- Hadassah Medical Organization