Clinical trials: Middle Ear Effusion
Otitis Media, Otitis Media With Effusion
Coherent Optical Detection of Middle Ear Disease
The purpose of this project is to see if optical coherence tomography (OCT), a new technology acting as an ultrasound for the ear, facilitates accurately diagnosing acute otitis media (AOM) and otitis media with effusion (OME) in…
- Conditions
- Otitis Media, Otitis Media With Effusion, Otitis Media Acute
- Trial name
- OCTII (NCT05353569)
- Testing
- OCT Device(s)
- Where
- 2 sites in United States
- Volunteers
- 235 people
- Sponsor
- Medical College of Wisconsin
Otitis Media With Effusion
Clinical Study of the Tympanostomy Tube Delivery System
The objective of this investigational study is to evaluate the safety and performance of the Acclarent Tympanostomy Tube Delivery System (TTDS) for the placement of the Tympanostomy Tube [TT(s)] in patients indicated for such…
- Trial name
- inVENT (NCT00939796)
- Testing
- Acclarent Tympanostomy Tube Delivery System
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media With Effusion (OME), Otitis Media With Effusion in Children
Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion
Otitis media with effusion (OME) is a common condition in which fluid collects behind the eardrum without signs of infection. It can cause hearing problems and discomfort.
- Conditions
- Otitis Media With Effusion (OME), Otitis Media With Effusion in Children, Breathing Exercise
- Trial name
- NCT06967506
- Testing
- Blowing exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Uşak University
Otitis Media, Otitis Media Chronic
SWIR Otoscopy Study
The aim of this study is to provide preliminary data to support future studies to demonstrate that the short wave infrared (SWIR) otoscope is a better diagnostic tool than a white light otoscope for diagnosing middle ear…
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion
- Trial name
- NCT06944795
- Testing
- SWIR device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Otitis Media With Effusion, Acute Otitis Media
Evaluation of the Tympanostomy Tube Delivery System
The purpose of this study is to evaluate the performance and safety of the Tympanostomy Tube Delivery System (TTDS) for chronic otitis media or recurrent acute otitis media.
- Trial name
- inVENT-OR (NCT01202578)
- Testing
- tympanostomy tube
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Children
This clinical trial was conducted in a population where tympanic membrane perforation occurs in 60% infants in the first year of life.
- Trial name
- COMIT1 (NCT00539149)
- Testing
- Amoxycillin
- Where
- Australia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Otitis Media With Effusion
The Efficacy of Nasal Steroids in Treatment of Otitis Media With Effusion: Acomparative Study
Otitis media with effusion (OME) is defined as effusion in the middle ear without signs and symptoms of an acute infection. It is a leading cause of hearing impairment in children, and its early and proper management can avoid…
- Trial name
- Efficacy (NCT03491098)
- Testing
- Mometasone Furoate spray, prednisolone sodium phosphate 15mg, hypertonic sea water solution spray
- Volunteers
- 60 people
- Sponsor
- Muteea Mubark Salmen Bakuwiri
Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps
The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear.
- Trial name
- NCT03975842
- Testing
- Sinonasal and otologic evaluation
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Recurrent Acute Otitis Media, Otitis Media With Effusion With Hearing Impairment
Study of Different Kinds of Ear Tubes
There are different kinds of ear tubes that may be inserted into the tympanic membrane to relieve recurrent acute otitis and hearing impairment due to otitis media with effusion. The tubes differ in size, shape and material.
- Trial name
- NCT00809601
- Testing
- Insertion of a specific type of ventilation tube through the tympanic membrane
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Danderyd Hospital
Hearing Impaired Children, Glue Ear
Exploring Interventions for Glue Ear During Covid-19
During the Coronavirus pandemic children's hearing services are closed or reduced and grommet operations are part of the lowest priority group.
- Conditions
- Hearing Impaired Children, Glue Ear, Hearing Loss, Conductive
- Trial name
- BIG-C (NCT04427631)
- Testing
- Bone conduction headphones
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Cambridgeshire Community Services NHS Trust
Otitis Media With Effusion
Suitable Method for Routine Diagnostics of EER in Children With Otitis Media With Effusion
The aim of the study was detection of pepsin in effusion in children with OME using Peptest as new quick and cheap method of detection and comparison results with results of other studies in which pepsin was detected by more…
- Trial name
- NCT02183974
- Testing
- Peptest
- Where
- Czechia
- Volunteers
- 44 people
- Sponsor
- University Hospital Ostrava
Otitis Media, Otitis Media Effusion
Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media
The goal of this clinical trial is to learn whether osteopathic manipulative treatment, or OMT, can reduce the need for tympanostomy tube surgery in children with recurrent or chronic otitis media who have been referred to an…
- Conditions
- Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children
- Trial name
- NCT07639775
- Testing
- Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sarah Vidal
Otitis Media, Conductive Hearing Loss
The Influence of The Ear Popper on Serous Otitis Media and on the Accompanying Conductive Hearing Loss in Children
This study is designed to check the effect of the use of the ear popper device on serous otitis media in children and on the conductive hearing loss accompanying the otitis.
- Trial name
- NCT00393159
- Testing
- Ear Popper
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Otitis Media With Effusion, Healthy
The URT and Middle Ear Microbiota in Health and During Chronic OME
This study analyses which bacteria are present in the middle ear space and adjacent upper respiratory tract niches in healthy people and in patients suffering from chronic otitis media with effusion (OME; glue ear).
- Trial name
- NCT03109496
- Testing
- Collection of body fluids/swabs
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Antwerp
Otorrhea, Otitis Media With Effusion in Children
Otiprio Versus Ciprodex Tympanostomy Tube Outcomes
Otolaryngologists routinely administer ear drops at the time of tympanostomy tube placement in order to prevent tube otorrhea; however, there is a lack of consensus as to which drops are the most effective, and whether a…
- Trial name
- NCT03347461
- Testing
- Otiprio, Ciprodex
- Where
- United States
- Sponsor
- Boston Medical Center
Otits Media With Effusion
Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial
Brief Summary - OMENUTS Trial Otitis media with effusion (OME) is a condition in which fluid accumulates in the middle ear, causing conductive hearing loss, ear fullness, tinnitus, and Eustachian tube dysfunction.
- Trial name
- OMENUTS (NCT07721610)
- Testing
- Omega-3-based nutraceutical combination (Otoair Flogo), Bilastine 20 mg, Intranasal mometasone furoate spray
- Where
- Italy
- Volunteers
- 501 people
- Sponsor
- Isola Tiberina - Gemelli Isola Hospital, Rome, Italy
Chronic Eustachian Tube Dysfunction, Chronic Recurrent Otitis Media
Balloon Eustachian Tuboplasty in Treatment of Chronic Eustachian Tube Dysfunction
The prevalence of Eustachian tube (ET) dysfunction in adults reaches 1%. It causes a feeling of fullness in the ear, otalgia and hearing loss and can lead to recurrent acute otitis media, development of chronic otitis media with…
- Conditions
- Chronic Eustachian Tube Dysfunction, Chronic Recurrent Otitis Media, Effusion After Tympanostomy
- Trial name
- NCT03556215
- Testing
- Eustachian tube dilatation device, Myringotomy
- Where
- 2 sites in Czechia
- Volunteers
- 55 people
- Sponsor
- University Hospital Ostrava
Otitis Media
The Effects of Ventilation Tubes - The SIUTIT Trial
The prevalence of otitis media among Greenlandic children is one of the highest in the world and twenty per cent of schoolchildren have impaired hearing in the frequencies for normal speech.
- Trial name
- SIUTIT (NCT02490332)
- Testing
- Ventilation tube treatment
- Where
- 6 sites in Greenland
- Volunteers
- 31 people
- Sponsor
- Zealand University Hospital
Otitis Media Recurrent, Middle Ear Infection
Utility of Advanced Ultrasound Otoscope In The Diagnosis of AOM
The objective of this study is to collect ultrasound signal information and visual otoscopic images with an engineering prototype device for children scheduled for tympanostomy tube surgery for the purpose of algorithm…
- Conditions
- Otitis Media Recurrent, Middle Ear Infection, Ear Infection
- Trial name
- NCT06429709
- Testing
- Advanced Ultrasound Otoscope
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Baylor College of Medicine
Otitis Media
Eustachian Tube Growth and Development
This study is to measure over time (from 3 years until 13 years of age) Eustachian tube function (the way the Eustachian tube works) and facial growth in groups of children with two types of middle-ear disease and with little…
- Trial name
- NCT00422929
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh