Clinical trials: Middle Rectal Cancer
Rectum Cancer
Clinical Effect of Neoadjuvant Hierarchical Treatment Based on Chemotherapy
Clinical effect of neoadjuvant hierarchical treatment based on chemotherapy for T3-4N0-2M0 middle and lower rectal cancer
- Trial name
- NCT03071198
- Testing
- TME, Concurrent chemo-radiotherapy, neoadjuvant CT
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Locally Advanced Rectal Cancer
Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer
This is an open, prospective, multi-center, single-arm phase II clinical study assessing the efficacy and safety of neoadjuvant chemoradiotherapy combined with PD-1 inhibitor and thymalfasin in patients with pMMR/MSS locally…
- Trial name
- NCT06056804
- Testing
- capecitabine, tislelizumab, thymalfasin
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Colorectal Cancer, Head and Neck Cancer
NGR-TNF in Treating Patients With Advanced Solid Tumors
RATIONALE: Targeted therapy with tumor necrosis factor combined with a fusion protein may stop the growth of solid tumors by stopping blood flow to the tumor.
- Conditions
- Colorectal Cancer, Head and Neck Cancer, Kidney Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00098943
- Testing
- CNGRC peptide-TNF alpha conjugate
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 70 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Rectal Cancer, Radiation
SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer
Primary Objectives： Evaluate the complete response rate (CR rate) and safety of short - course radiotherapy combined with ivonesimab (AK112) in patients with pMMR/MSS mid - low rectal cancer.
- Conditions
- Rectal Cancer, Radiation, AK112
- Trial name
- STAR (NCT07162714)
- Testing
- radiotherapy, Ivonescimab (20mg/kg Q3W), Non-operative Management
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhejiang Cancer Hospital
Rectal Cancer
Local Excision of Clinical T3 Rectal Adenocarcinoma Showing Major Response(ycT0-1) After Neoadjuvant Chemoradiotherapy
The purpose of this study is evaluation of the safety and the efficacy of transanal local excision in patients with cT3 rectal cancer which was downstaged into ycT0-1 after neoadjuvant chemoradiotherapy.
- Trial name
- NCT02490709
- Testing
- Local excision
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- National Cancer Center, Korea
Neoplasms, Colorectal, Neoplasm Metastasis
A Longitudinal Study of Colorectal Cancer Patients With Metastatic Disease in Middle-Norway
The main objective is to provide original research results that may change clinical practice related to metastatic colorectal cancer.
- Trial name
- NCT02395224
- Testing
- cancer treatment and follow-up according to current regional and national guidelines
- Where
- 7 sites in Norway
- Volunteers
- 354 people
- Sponsor
- Norwegian University of Science and Technology