Clinical trials: Middle-aged and Older Adults
Hot Flashes, Sleep
LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot Flashes
Vasomotor symptoms are the most common symptoms seen during climacterium. The hypoestrogenic state causes dysfunction of hypothalamic preoptic area, a thermoregulatory center.
- Conditions
- Hot Flashes, Sleep, Menopause, Cardiovascular Diseases
- Trial name
- NCT05892211
- Testing
- Polysomnography, Skin conductance, ALU and LINE-1 DNA methylation analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Ultrasound Lipolysis, Cryolipolysis
Ultrasound Lipolysis Versus Cryolipolysis On Lipid Profile Levels In Centrally Obese Middle Aged Men
The study compares the effects of ultrasound lipolysis and cryo lipolysis on cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, body mass index, skin thickness, waist circumference, and waist hip ratio…
- Conditions
- Ultrasound Lipolysis, Cryolipolysis, Lipid Profile, Central Obesity
- Trial name
- NCT06658639
- Testing
- Ultrasound lipolysis, Cryolipolysis, Low Caloric Diet
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Blood Pressure, Endothelial Dysfunction
Neurovascular Effects of Empagliflozin
The goal of this clinical trial is to examine whether empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, improves vascular and autonomic function in adults with prehypertension.
- Trial name
- NEURO-EMPA (NCT07799441)
- Testing
- Empagliflozin (EMPA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanokwan Bunsawat
Metabolic Syndrome, Obesity
Improvement of Metabolic Health After Thylakoid Supplementation
Objective: The purpose of this study was to investigate the possible effects of green-plant thylakoid supplementation to a restricted diet intervention study in overweight to obese men.
- Trial name
- NCT02687295
- Testing
- Thylakoids, Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Region Skane
Overweight and Obesity
Web-Based Weight Loss & Weight Maintenance Intervention for Older Rural Women, Also Known as Women Weigh-in for Wellness
This project will evaluate an Internet delivery strategy to address weight loss and maintenance among rural midlife and older women.
- Trial name
- NCT01307644
- Testing
- Experimental: Web-based only (WO) weight intervention, Experimental: WO plus peer-led discussion board (WD), Experimental: WO & professional email counseling (WE)
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Nebraska
Constipation
Impact of a Synbiotic Containing Fructo-oligosaccharides and Bifidobacteria in Middle-aged Adults
The aim of the study is to evaluate the impact of a synbiotic containing fructo-oligosaccharides (FOS) and Bifidobacteria (VES002 LMG P-28149) on intestinal transit in middle-aged subjects characterized by a low number of…
- Trial name
- NCT04283266
- Testing
- Synbiotic
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vesale Pharmaceutica
Healthy
Efficacy and Safety of Ginkgo Biloba in Middle-aged Cognitively Intact Adults
The primary objective of this study was to assess the efficacy and safety of Gingko biloba film-coated tablets in improving cognitive function and neuropsychological functioning of middle-aged cognitively intact adults.
- Trial name
- NCT02181972
- Testing
- Gingko biloba
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Exercise Training
Football 4 Health in Middle-aged to Older Adults
Ageing in humans is accompanied by a progressive decline in lower-limb muscle power production. In addition to a decline in musculoskeletal fitness, ageing is associated with a reduction in cardiovascular and metabolic fitness.
- Trial name
- NCT05722899
- Testing
- Football training
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy, Physical Examination
Walking Aid Assessment, Arm Strength and Force Under the Foot in Normal Subjects
This study will collect biomedical performance data on walking characteristics in normal, healthy people when walking with walking aids and when walking unaided.
- Conditions
- Healthy, Physical Examination, Middle Age, Aged
- Trial name
- NCT05092932
- Testing
- Normal Foot Force
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Aging
Safety & Efficacy of Nicotinamide Riboside Supplementation for Improving Physiological Function in Middle-Aged and Older Adults
The purpose of this study is to assess the efficacy of supplementation with the Nicotinamide Adenine Dinucleotide (NAD+) precursor compound, Nicotinamide Riboside (NR), for improving physiological function (vascular, motor, and…
- Trial name
- NCT02921659
- Testing
- Niagen™
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder