Clinical trials: Migraine, completed
Headache
Acceptance and Commitment Therapy vs Medical Treatment as Usual Wait-list Control for Primary Headache Sufferers
Research to date suggests that individuals with headache use avoidance as a way to manage their pain. Despite the wide use of avoidance as a coping mechanism of headache triggers, very little empirical evidence exist to support…
- Trial name
- ALGEA (NCT02734992)
- Testing
- ACT+ MTAU, Waitlist Control +MTAU
- Where
- Cyprus
- Volunteers
- 100 people
- Sponsor
- University of Cyprus
Acute Migraine Headache
Comparison of Oral Paracetamol and Zolmitriptan Efficacy in the Treatment of Acute Migraine in Emergency Department
Migraine is a chronic and sometimes progressive disorder, characterized by headache, recurrent episodes, and other associated symptoms.
- Trial name
- NCT03145467
- Testing
- Paracetamol, Zolmitriptan
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Pamukkale University
Migraine
Safety, Tolerability and Drug- Drug Interaction Study of Ubrogepant With Erenumab or Galcanezumab in Participants With Migraine
This study will evaluate the potential for a pharmacokinetic (PK) interaction and provide safety and tolerability information when ubrogepant and erenumab or ubrogepant and galcanezumab are co-administered.
- Trial name
- NCT04179474
- Testing
- Ubrogepant, Erenumab, Galcanezumab
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Allergan
Migraine Without Aura
Effect of PACAP38/VIP on Migraineurs Measured by Magnetic Resonance
The purpose of this study is to examine and compare the effect of pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide (VIP) on intracranial arteries and neuronal activity in…
- Trial name
- NCT01471990
- Testing
- Pituitary Adenylate Cyclase-Activating Polypeptide-38, Vasoactive Intestinal Peptide
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Migraine, Acute Treatment of Migraine
Nerivio Efficacy by Time of Treatment Onset
This is a Post-marketing study investigating the impact of treatment time onset with Nerivio on the efficacy of Remote Electrical Neuromodulation (REN) for the acute treatment of migraine.
- Trial name
- NCT06976723
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 55,261 people
- Sponsor
- Theranica
Migraine
Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines?
The purpose of this study is to determine if Rizatriptan, a migraine medication, lowers motion sickness in migraine sufferers.
- Trial name
- NCT00360282
- Testing
- Rizatriptan
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Pittsburgh
Migraine Disorders
Effects of tDCS and Physical Therapy in Chronic Migraine
The aim of this clinical study is to compare the effects of tDCS, physiotherapy, and their association with the intensity in women with Chronic Migraine.
- Trial name
- NCT05706077
- Testing
- active tDCS, real Physical Therapy
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Headache Disorders
Occipital Nerve Stimulation to Treat Chronic Headaches
The purpose of this study is to evaluate the safety and efficacy of a implantable device, called the bion(R), in the treatment of chronic headache.
- Trial name
- NCT00205894
- Testing
- bion microstimulator
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Boston Scientific Corporation
Migraine Disorders
Phase I, Open Label, Single-Dose, Four Way Crossover Study to Compare the PK of NP101 With Oral Imitrex® (50mg) in Migraine Subjects During an Acute Migraine Attack and During a Non-Migraine Period
To compare the pharmacokinetics of NP101 with a currently approved oral formulation of Imitrex® (50 mg) in migraine subjects both during an acute migraine attack and during a non-migraine period.
- Trial name
- NP101-011 (NCT00723983)
- Testing
- Sumatriptan succinate, NP101 Study Patch
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- NuPathe Inc.
Cyclic Vomiting Syndrome
Staccato Granisetron® (AZ 010) for the Treatment of Cyclic Vomiting Syndrome
This is a multicenter, randomized, double-blind, parallel group, placebo-controlled, efficacy and safety study of adult outpatients diagnosed with CVS and experiencing recurring episodes of stereotypical vomiting.
- Trial name
- NCT04645953
- Testing
- 3mg AZ-010, 1mg AZ010
- Where
- 18 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
Migraine, Worker Health
Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine
Migraine is a common neurological disease causing significant disability worldwide, with an estimated global prevalence of 14.4%.
- Conditions
- Migraine, Worker Health, Sensitization, Musculoskeletal Pain
- Trial name
- NCT07554664
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Bozok University
Migraine
A Dose-Finding Study of MK-1602 in the Treatment of Acute Migraine (MK-1602-006)
The purpose of this study is to assess the effectiveness, safety and tolerability of a range of doses of MK-1602 versus placebo in the treatment of acute migraine.
- Trial name
- NCT01613248
- Testing
- MK-1602, Rescue medication
- Volunteers
- 834 people
- Sponsor
- Allergan
Workplace Migraine Treatment
Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?
Researchers want to learn about work productivity after treatment of a migraine headache with your usual migraine medication as compared to your work productivity after treatment with Treximet.
- Trial name
- NCT01086358
- Testing
- Triptan, Treximet 85Mg-500Mg Tablet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Migraine Disorders
A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 2 of 2)
This is a randomized, double-blind, placebo-controlled, crossover, two-attack, out-patient, early-intervention evaluation of subjects who have migraine with or without aura and who discontinued use of short acting triptan(s)…
- Trial name
- NCT00382993
- Testing
- Combination Product (sumatriptan succinate/naproxen sodium)
- Where
- 28 sites in United States
- Volunteers
- 169 people
- Sponsor
- GlaxoSmithKline
Migraine
Telehealth Behavioral Migraine Management
This project aims to develop the protocol and obtain feasibility and acceptability information for Telehealth Behavioral Migraine Management in a single-arm pre-post pilot study.
- Trial name
- TeleBMM (NCT03982316)
- Testing
- Telehealth Behavioral Migraine Management, Education Modules
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Albert Einstein College of Medicine
Chronic Pain, Headache, Migraine
Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
Study Purpose: This study will explore the feasibility of administering Holographic Memory Resolution® (HMR) to adults who are experiencing chronic pain for 6 months or more.
- Conditions
- Chronic Pain, Headache, Migraine, Stress Disorders, Post-Traumatic
- Trial name
- NCT05001399
- Testing
- Holographic Memory Resolution® (HMR)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Billings Clinic
Migraine
A Randomized, Sham-controlled Study of gammaCore ® (nVNS) for Prevention of Episodic Migraine
A prospective, double-blind, randomized, sham-controlled, multicentre investigation.
- Trial name
- NCT02378844
- Testing
- gammaCore®-R
- Where
- 22 sites in Belgium, Denmark and 6 more
- Volunteers
- 477 people
- Sponsor
- ElectroCore INC
Migraine Disorders
Lacosamide Versus Propranolol in Migraine
Investigators aim to compare the effect of lacosamide versus propranolol in migraine by assessing the absolute reduction in MMD in each group, the percentage of patients who achieved ≥ 50% reduction in the monthly headache days…
- Trial name
- NCT05851781
- Testing
- Lacosamide tablet, Propranolol
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Kafrelsheikh University
Migraines
A Nutritional Intervention for Migraines-2
The purpose of the study is to assess whether, in individuals with migraines, a low-fat, vegan diet improves pain more effectively than a control supplement or a placebo.
- Trial name
- WCCR-MIG2 (NCT01699009)
- Testing
- Plant based diet, an unrestricted diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Physicians Committee for Responsible Medicine
Episodic Migraine, Migraine With Aura
Mi-Helper Transnasal Cooling for Acute Treatment of Migraine
This is a prospective, double-blind, sham-controlled, randomized clinical trial . This study aims to assess the efficacy, safety, tolerability, and the optimal dose of the Mi-Helper transnasal cooling device for acute treatment…
- Conditions
- Episodic Migraine, Migraine With Aura, Migraine Without Aura, Migraine
- Trial name
- NCT06051604
- Testing
- Mi-Helper
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- CoolTech LLC
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