Clinical trials: Migraine, completed
Vestibular Migraine
Galcanezumab for Vestibular Migraine
Vestibular migraine (VM) has been recognized a distinct subtype of migraine that causes dizziness as the predominant symptom. Criteria for diagnosis have been adopted by the Barany Society.
- Trial name
- NCT04417361
- Testing
- Galcanezumab Prefilled Syringe
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Migraine
A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine
This is an open-label, twelve-month safety study. There is a screening period followed by a run-in period to record migraine activity.
- Trial name
- ADAM (NCT03282227)
- Testing
- M207 Microneedle System
- Where
- 31 sites in United States
- Volunteers
- 342 people
- Sponsor
- Zosano Pharma Corporation
Chronic Migraine
Study to Evaluate the Efficacy of Intranasal Kinetic Oscillation Stimulation in the Preventive Treatment of Chronic Migraine
The efficacy of intranasal kinetic oscillation stimulation using the Chordate System S211 as a preventative treatment will be examined in patients diagnosed with chronic migraine.
- Trial name
- NCT03400059
- Testing
- Chordate System S211 in treatment mode
- Where
- 10 sites in Finland, Germany
- Volunteers
- 144 people
- Sponsor
- Chordate Medical
Headache, Migraine
Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
To investigate headache score and accompanying symptoms during and after infusion of the natriuretic peptides.
- Trial name
- NCT01637662
- Testing
- Natriuretic peptides
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Chronic Migraine, Olfactory Acuity
Smell Sensitivity in Chronic Migraine: A Case-Control Study
Olfactory impairment is a common symptom of neurologic disorders and may be related to dopaminergic dysfunction. Studies show that patients with migraine show increased sensitivity to light and sound.
- Trial name
- NCT01687088
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University
Migraine
A Study Investigating the Movement of Lu AG09222 Into, Through, and Out of the Body of Healthy Caucasian, Chinese, and Japanese Participants
The main goal of the study is to learn more about how the body absorbs and eliminates Lu AG09222 after a single dose is injected under the skin.
- Trial name
- NCT05304910
- Testing
- Lu AG09222
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Chronic Migraine, Chronic Migraine, Headache
A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine
This is a phase 2, double-blind, randomized, multicenter, placebo-controlled, three arm parallel study to evaluate the efficacy and safety of two different dosages (30 IU daily and 60 IU daily) of TNX-1900 in patients with…
- Conditions
- Chronic Migraine, Chronic Migraine, Headache, Chronic Migraine Without Aura, Aura Migraine
- Trial name
- PREVENTION (NCT05679908)
- Testing
- TNX-1900
- Where
- 26 sites in United States
- Volunteers
- 88 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Chronic Migraine
Use of the Tx360 Nasal Applicator in the Treatment of Chronic Migraine
Migraine imposes a substantial burden on patients in terms of diminished daily functioning, quality of life, and financial loss.
- Trial name
- Tx360 (NCT01709708)
- Testing
- Marcaine, Saline
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Tian Medical Inc.
Migraine With Aura, Migraine Without Aura
Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment
The purpose of this study is to show the efficacy of promethazine in management of patients with moderate to severe migraine
- Trial name
- NCT01814189
- Testing
- Sumatriptan+Promethazine (SPr)
- Where
- Iran
- Volunteers
- 350 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Migraine Headache, Episodic
A Non-Invasive Neuromodulation Device for Treatment of Migraine Headache
This is a randomized, blinded study designed to assess the efficacy of a portable, non-invasive neuromodulation system for the treatment of episodic migraine headaches.
- Trial name
- NCT01899040
- Testing
- neuromodulation for episodic migraine headache
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Scion NeuroStim
Headache, Migraine
The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance Angiography
To examine the ability of MRA to measure the effect of GTN on the intra-cranial vascular response during the GTN-induced headache in healthy volunteers.
- Conditions
- Headache, Migraine, MR-Angiography, Healthy Volunteers
- Trial name
- NCT00256802
- Testing
- MR-angiography, GTN
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Episodic Migraine
Cerebri Biofeedback Feasibility Trial
The purpose of this study is to investigate feasibility, usability, safety, efficacy, and tolerability of Cerebri biofeedback treatment for adults with episodic migraine.
- Trial name
- CER-MIG-1 (NCT05454319)
- Testing
- Biofeedback
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Nordic Brain Tech AS
Headache
Oxygen Therapy for the Treatment of Undifferentiated Headache in the Emergency Department
This study will randomly assign emergency department patients seeking treatment for a headache to one of three groups. The first group will receive standard emergency care as determined by the treating physician, the second group…
- Trial name
- NCT00856232
- Testing
- Medical Air, Oxygen
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Chronic Migraine
OnabotulinumtoxinA Injections in Chronic Migraine, Targeted to Sites of Pericranial Myofascial Pain
This study was an observational, open-label, cohort-study conducted in accordance with the principles of the Helsinki Declaration.
- Trial name
- NCT03175263
- Volunteers
- 57 people
- Sponsor
- University Hospital, Limoges
Migraine in Adolescents
Bringing Relief to Adolescents Naturally Using Melatonin for Migraine
Migraine in adolescents is common and effective and safe preventive treatments are needed. This is a pilot randomized controlled trial of melatonin versus placebo for migraine prevention in adolescents 12-17 years old.
- Trial name
- BRAiN-M (NCT02344316)
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Amy Gelfand
Migraine Without Aura
Effect of Sildenafil in Individuals With Migraine Pretreated With Erenumab
An outstanding scientific question, that merits further investigation, is whether dilation of intracranial arteries is implicated in the pathogenesis of cephalic pain in migraine.
- Trial name
- COMPETE (NCT05889455)
- Testing
- Sildenafil
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Danish Headache Center
Migraine
Standardized sTudy With Almotriptan in eaRly Treatment of Migraine
This is a observational, open, prospective, single arm cohort study within authorized SPC conditions to describe the effectiveness of Almotriptan in treating acute migraine attacks when pain is mild and in the first hour of pain…
- Trial name
- START (NCT00725140)
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 501 people
- Sponsor
- Almirall, S.A.
Migraine
Synergistic Impact of Postural Correction Interventions and Sustained Natural Apophyseal Glides in Migraine
This study was conducted to evaluate the synergistic impact of postural correction interventions and sustained natural apophyseal glides on severity, quality of life and disability in patients with migraine.
- Trial name
- NCT07403175
- Testing
- Sustained Natural Apophyseal Glides, Postural Correction Exercises, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Menstrually Associated Migraine
A Randomized Trial of Frovatriptan for the Intermittent Prevention of Menstrual Migraine
The primary objective of this study was to determine whether frovatriptan was effective in the prevention of menstrually associated migraine (MAM) headaches when compared to placebo.
- Trial name
- NCT00644033
- Testing
- Frovatriptan
- Where
- United States
- Volunteers
- 579 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
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