Clinical trials: Migraine, completed
Migraine Without Aura
Efficacy Study of Acupuncture in the Prevention of Migraine Without Aura
Acupuncture is commonly used for the prevention of migraine, while the evidence for its efficacy is still uncertain. Current studies have not been able to determine whether the efficacy of acupuncture is due to the actual…
- Trial name
- NCT02765581
- Testing
- Verum acupuncture, Usual care
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Wei Wang
Headache, Migraine
Headache Inducing Characteristics and Possible Changes in Cerebral Blood Flow After Administration of PGE2
Before, during and after intravenous administration of PGE2 we score/measure headache, rCBF, blood flow in the middle cerebral artery and diameter of superficial temporal artery and correlate that to known pathophysiology of…
- Trial name
- NCT00374530
- Testing
- PGE2
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine Disorders, Headache, Migraine
Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pediatric Pain Population
The purpose of the research is to examine the outcomes of pediatric patients receiving Botulinum toxin type A (Botox ®) for the treatment of migraine.
- Conditions
- Migraine Disorders, Headache, Migraine, Pediatrics
- Trial name
- NCT03055767
- Testing
- OnabotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of California, Irvine
Headache, Migraine
Effect of Transmagnetic Stimulation on Conditioned Pain Modulation (CPM)
While some indications of the neural circuits involved in the Conditioned Pain Modulation (CPM) process are now available, there is still need to clarify what parts of the brain are essential for this process, whether the…
- Trial name
- NCT01501045
- Testing
- TMS system MagPro x100, Tonica Elektronik A/S, Denmark
- Where
- Israel
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Migraine Disorders, Aphasia
Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention
Stroke-like migraine attacks after radiation therapy-also known as SMART syndrome-constitute a rare condition typically characterized by headache, seizures, vision abnormalities, hemiparesis, and aphasia.
- Trial name
- NCT03662295
- Testing
- Language treatment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Quality Living, Inc.
Migraine
Imaging the Migraine Brain Pre- and Post-Erenumab
Researchers are trying to determine if there is a difference between brain images of subjects that do respond to treatment with erenumab and subjects who do not respond to treatment with erenumab using Magnetic Resonance Imaging…
- Trial name
- NCT03773562
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Rapidly Escalating Migraine
Pilot Study of Two Different Strengths of DFN-11 Injection for Rapidly Escalating Migraine
Pilot study to compare the efficacy and safety of two strengths of injections of subcutaneous DFN-11 in subjects with rapidly escalating migraine headaches.
- Trial name
- NCT02571049
- Testing
- DFN-11
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Migraine, Migraine Disorders
Integrative Migraine Pain Alleviation Through Chiropractic Therapy
This pilot study evaluates the addition of chiropractic treatment to conventional neurological care in the treatment of migraine headaches in adult women.
- Conditions
- Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura
- Trial name
- IMPACT (NCT03177616)
- Testing
- Chiropractic Treatment
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Harvard University Faculty of Medicine
Migraine, Cluster Headache
mBrain-21 : a Three-month Study on Context-awareness, Physiological Monitoring, and Machine Learning in Migraine and Cluster Headache
This study collects data from migraine and cluster headache patients during a three-month study. Contextual data (e.g. location or smartphone usage) and physiological variables will be used to assist machine learning algorithms…
- Trial name
- MBRAIN-21 (NCT04983186)
- Testing
- Wearable sensor and smartphone application
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Migraine
Efficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of Migraine
A study to evaluate the long-term safety, tolerability, and efficacy of subcutaneous (SC) administration of TEV-48125 in adult participants with chronic migraine (CM) or episodic migraine (EM).
- Trial name
- HALO (NCT02638103)
- Testing
- Fremanezumab
- Where
- 139 sites in United States, Canada and 7 more
- Volunteers
- 1,890 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine, Preventive Treatment
Prediction of Migraine Prevention Efficacy Based on Individual's Pain Modulation
A major reason for the substantial underuse of pharmacological prevention of migraine is its inadequate efficacy, since only ~50% of patients respond to a specific agent.
- Trial name
- NCT02101892
- Testing
- Amitriptyline
- Where
- Israel
- Volunteers
- 54 people
- Sponsor
- Rambam Health Care Campus
Migraine Disorders
A Study to Determine the Effect of Sumatriptan and Naproxen Sodium Combination Tablet, Sumatriptan Tablet, and Naproxen Sodium Tablet on Blood Pressure When Treating Migraine Headaches That Occur During a 6-month Period
The purpose of this study is to test the effect on blood pressure of sumatriptan and naproxen sodium combination tablets, tablets containing only sumatriptan, and tablets containing only naproxen sodium when these drugs are taken…
- Trial name
- NCT00792636
- Testing
- sumatriptan and naproxen sodium combination tablet, sumatriptan tablet, naproxen sodium tablet
- Where
- 49 sites in United States
- Volunteers
- 407 people
- Sponsor
- GlaxoSmithKline
Migraine
Medicine Abuse Headache
In patients with MOH, we will evaluate the impact of educative telephone coaching on the number of days with headache over the month preceding the appointment.
- Trial name
- CAM-ET (NCT01170793)
- Testing
- educative telephone coaching (ETC)
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Bordeaux
Migraine, Migraine With Aura
A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine
Study STS101-003 is a multi-center, multiple dose (PRN), open-label, 12-month study to evaluate the safety and tolerability of STS101 (dihydroergotamine nasal powder) in the acute treatment of migraine.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- ASCEND (NCT04406649)
- Testing
- Dihydroergotamine
- Where
- 44 sites in United States
- Volunteers
- 482 people
- Sponsor
- Satsuma Pharmaceuticals, Inc.
Right-to-left Shunt, Migraine
Registry of Right-to-left Shunt Detection by Contrast-enhanced Transcranial Doppler in Chinese Population
The purpose of the study is to evaluate the prevalence and extent of right-to-left shunt (RLS) in Chinese migraineurs, and the morbidity of silent cerebral infarction in migraineurs.
- Conditions
- Right-to-left Shunt, Migraine, Cerebral Infarction
- Trial name
- NCT02425696
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Yingqi Xing
Migraine, Neuropathic Pain
Feasibility and Effectiveness of a Specific App to Delivery Mindfulness Sessions
A standardized behavioural approach based on mindfulness delivered mainly by a specific APP on android will be developed and applied for patients with chronic pain conditions, as migraine and neuropathic pain.
- Trial name
- BE_BI_MIND_APP (NCT05101837)
- Testing
- Home program
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Sphenopalatine Ganglion Nerve Block
Sphenopalatine Ganglion Block Study
The goal of this clinical trial is to compare the administration and dosage of bupivacaine for sphenopalatine ganglion (SPG) nerve block.
- Trial name
- NCT05707754
- Testing
- Bupivacaine, angiocatheter
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Migraine, Medication Overuse Headache
Eptinezumab in Adults With Migraine and Medication Overuse Headache
This study evaluates the efficacy of eptinezumab to prevent migraine and headache in patients with the combined diagnosis of migraine and medication overuse headache
- Trial name
- Sunlight (NCT04772742)
- Testing
- Eptinezumab
- Where
- 40 sites in China, Georgia and 3 more
- Volunteers
- 193 people
- Sponsor
- H. Lundbeck A/S
Migraine
Efficacy of Fascia Exercises in Migraine Patients
Migraine, which is characterized by attacks and many accompanying symptoms, negatively affects the quality of life of patients. Although different methods have been tried for migraine, there is no definitive treatment approach…
- Trial name
- NCT06231615
- Testing
- Fascia exercises, Conventional physiotherapy and breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Yildirim Beyazıt University
Chronic Daily Headache
Intensive Meditation and Migraines: Effects on Health and Well Being
Participants completing training in intensive meditation and continuing frequent practice for one year would experience reduced frequency, duration and severity of headaches along with improved awareness of the triggers of their…
- Trial name
- NCT00663585
- Testing
- Vipassana Meditation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
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