Clinical trials: Migraine, completed
Migraine Headache
A Study of Galcanezumab (LY2951742) in Participants With Migraine Headache
The main purpose of this study is to evaluate whether the study drug known as galcanezumab is safe and effective in the prevention of migraine headaches.
- Trial name
- NCT02163993
- Testing
- Galcanezumab
- Where
- 40 sites in United States
- Volunteers
- 414 people
- Sponsor
- Eli Lilly and Company
Refractory Migraine
Pulsed Electromagnetic Field Therapy in the Refractory Migraine
Pulsed electromagnetic field (PEMF) as prophylactic treatment may prevent the attacks of migraine or decrease them even in the patients with refractory migraine.
- Trial name
- NCT01670214
- Testing
- pulsed electromagnetic field
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Niyayesh Clinic
Chronic Migraine, Headache
Onabotulinumtoxin Type A Reconstitution With Preserved Versus Preservative-free Saline in Chronic Migraine.
A growing body of literature on the cosmetic use of OnabotulinumtoxinA has suggested that the use of preserved saline exerts a local anesthetic effect, and reduces the procedure discomfort when used in reconstitution in lieu of…
- Trial name
- B-RECON (NCT03698409)
- Testing
- Preserved saline in reconstitution of Botox
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- State University of New York - Upstate Medical University
Migraine Headache
Cupping and Serkangabin Versus Conventional Migraine Treatment
Migraine is the most common recurrent headache. Current therapy of migraine headache consists of multiple drug groups for control of attack and prophylaxis against recurrent attacks.
- Trial name
- NCT01476930
- Testing
- cupping and serkangabin syrup, conventional migraine drug treatment
- Where
- Iran
- Volunteers
- 391 people
- Sponsor
- Birjand University of Medical Sciences
Migraine Headache
Treatment of Multiple Attacks of Acute Migraine (0462-025)
A study to evaluate rizatriptan for the treatment of multiple attacks of acute migraine compared to placebo.
- Trial name
- NCT00899379
- Testing
- rizatriptan benzoate
- Volunteers
- 473 people
- Sponsor
- Organon and Co
Acute Migraine
Long-term Safety Study of BHV-3500 (Zavegepant*) for the Acute Treatment of Migraine
The purpose of this study is to evaluate the long-term safety of BHV-3500/vazegepant intranasal in the acute treatment of migraine. BHV-3500, formerly "vazegepant", is now referred to as "zavegepant" (za ve' je pant).
- Trial name
- NCT04408794
- Testing
- Zavegepant (BHV-3500)
- Where
- 67 sites in United States
- Volunteers
- 974 people
- Sponsor
- Pfizer
Migraine, Classic Migraine
Potential Impact (Benefit) of Preventative Treatment With Topamax on the Effectiveness of Axert in the Acute Treatment of Migraine
The purpose of this study is to evaluate the impact of topiramate (migraine prevention medicine) on the effectiveness of almotriptan malate (acute migraine medicine) when treating acute migraine headaches.
- Conditions
- Migraine, Classic Migraine, Common Migraine
- Trial name
- NCT00210496
- Testing
- topiramate; almotriptan malate
- Volunteers
- 406 people
- Sponsor
- Janssen-Ortho LLC
Headache, Migraine
Hemodynamic and Headache-Inducing Effect of Intravenous Vasoactive Intestinal Peptide in Migraineurs
We hypothesized that infusion of VIP may induce headache/migraine in migraineurs and that VIP-induced headache may be associated with dilation of intra- and extracranial vessels.
- Conditions
- Headache, Migraine, Vasoactive Intestinal Peptide, Ultrasonography, Doppler, Transcranial
- Trial name
- NCT00272896
- Testing
- Vasoactive intestinal peptide
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Headache Center
Migraine With and Without Aura, Chronic Migraine
Migraine and Body Composition
This research is being done to look at the association between migraine and obesity.
- Conditions
- Migraine With and Without Aura, Chronic Migraine, Healthy Controls
- Trial name
- NCT01720862
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Migraine
Effect of Single Oral Doses of Lasmiditan When Coadministered With Single Oral Doses of Sumatriptan in Healthy Participants
This is a randomized, double-blind, three-period, cross-over study to investigate the effect of sumatriptan (Imitrex) 100 mg on the pharmacodynamics and pharmacokinetics of lasmiditan 200 mg.
- Trial name
- NCT03076970
- Testing
- lasmiditan 200 mg, Sumatriptan
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine
The Effectiveness of Almotriptan Malate (AXERT®) 12.5 Milligrams When Taken at the Onset of Migraine Pain
The purpose of this study is to evaluate the effectiveness and safety of AXERT when treating a migraine at the onset of headache pain, as compared to treating a migraine only after the headache pain has reached at least moderate…
- Trial name
- NCT00212823
- Testing
- almotriptan malate
- Volunteers
- 1,450 people
- Sponsor
- Ortho-McNeil Neurologics, Inc.
Cephalalgia
Protocol to Ease Acute Cephalalgia in Emergency-department
The purpose of this study is to determine if the use of a therapeutic and global protocol to relieve cephalalgia is helpful in the emergency department of Grenoble University Hospital.
- Trial name
- PEACE (NCT02236442)
- Testing
- Recommendation to use global headache treatment protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Episodic Migraine Headache
A Multicenter Assessment of LBR-101 in High Frequency Episodic Migraine
The purpose of this study is to determine whether monthly subcutaneous administration of LBR-101 (fremanezumab) is safe and provides migraine prevention in subjects with high frequency episodic migraine.
- Trial name
- NCT02025556
- Testing
- LBR-101 High Dose, LBR-101 Low Dose
- Where
- 63 sites in United States
- Volunteers
- 297 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine With Aura, Migraine Without Aura
Can DFN-15 Terminate Migraine With Allodynia?
The majority of migraineurs seeking secondary or tertiary medical care develop cutaneous allodynia during the course of migraine, a sensory abnormality mediated by sensitization of central trigeminovascular neurons in the spinal…
- Conditions
- Migraine With Aura, Migraine Without Aura, Allodynia
- Trial name
- NCT03472378
- Testing
- DFN-15
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Migraine, With or Without Aura
An Extension Study to Evaluate the Long-Term Safety and Tolerability of Ubrogepant in the Treatment of Migraine
This study will evaluate the long-term safety and tolerability of intermittent treatment with ubrogepant for the acute treatment of migraine over 1 year.
- Trial name
- NCT02873221
- Testing
- Ubrogepant, Usual Care
- Where
- 177 sites in United States
- Volunteers
- 1,254 people
- Sponsor
- Allergan
Migraine
Predictive Role of MIDAS Reduction at 3 Months for Erenumab Treatment
In 2021, the Italian Medicines Agency approved reimbursement of monoclonal antibodies targeting the CGRP pathway (CGRP-mAbs) as preventive therapies for patients with high frequency and chronic migraine (CM).
- Trial name
- Ere-MIDAS (NCT05442008)
- Testing
- Erenumab 70/140 mg s.c.
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Vestibular Migraine
The Effect of Bone-Conducted Stimulation on Rotary Chair Time Constants in Patients With Vestibular Migraines
The goal of this clinical trial is to learn if the Otolith Labs device can improve vestibular function of subjects with vestibular migraine.
- Trial name
- VIBRANT-VM (NCT06540235)
- Testing
- Otolith Device Active, Otolith Device Inactive
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Otolith Labs
Primary Headache Disorder
Oxygen Therapy for Headache
Headache is one of the common causes of emergency department admissions and constitutes approximately 2%. Although the exact mechanism is not clear, It is known that high-flow oxygen therapy is effective in headache treatment.
- Trial name
- NCT05511155
- Testing
- Oxygen therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Aksaray University Training and Research Hospital
Migraine
Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines
Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines.
- Trial name
- NCT00122278
- Testing
- Dexamethasone
- Where
- 3 sites in United States
- Volunteers
- 205 people
- Sponsor
- Montefiore Medical Center
Migraine
Study to Test an Approved Product in the Early Treatment of Migraine (0462-066)
The purpose of this study is to test the effectiveness of an approved drug in the early treatment of migraine.
- Trial name
- NCT00095004
- Testing
- MK0462, rizatriptan benzoate / Duration of Treatment: 1day
- Volunteers
- 167 people
- Sponsor
- Organon and Co
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