Clinical trials: Migraine, completed
Migraine
Migraine Induction Properties of PACAP-38 After Eptinezumab in Migraine Without Aura Patients.
To investigate whether administration of calcitonin gene-related peptide (CGRP) binding monoclonal antibodies eptinezumab prevents pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) induced migraine attacks in…
- Trial name
- NCT05635604
- Testing
- Eptinezumab, PACAP-38
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- Danish Headache Center
Migraine; Status
Effect of Acupressure in Migraine: Single-blinded, Randomized, Controlled Clinical Trial
Background : Migraine is one of the most complex, prevalent, debilitating neurologic disorder in the world. In clinical experience, there are limitation over western medicine for migraine, especially some extra adverse effects.
- Trial name
- NCT04429048
- Testing
- Acupressure elastic band (Sea-Band), General elastic band (no bud)
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- National Taiwan University Hospital
Headache, Cephalgia
Effect of Osteopathic Manipulative Treatment for Patients With Chronic Headache
Participants with chronic or recurrent headache, unrelated to any known pathology or disease, will be randomly assigned to one of four interventions: Osteopathic manipulation of the body other than the head, osteopathic…
- Conditions
- Headache, Cephalgia, Migraine
- Trial name
- OMTHA (NCT01332864)
- Testing
- Osteopathic Manipulative Treatment (OMT), Light touch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Western University of Health Sciences
Migraine
A Study of LY3451838 in Participants With Migraine
The reason for this study is to see if the study drug LY3451838 is safe and effective in participants who have migraine that have not responded to other preventive treatments.
- Trial name
- NCT04498910
- Testing
- LY3451838
- Where
- 9 sites in United States
- Volunteers
- 38 people
- Sponsor
- Eli Lilly and Company
Migraine, Migraine With Aura
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine
Study STS101-002 is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to evaluate the efficacy, safety, and tolerability of single doses of STS101 (dihydroergotamine nasal powder) in the acute…
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- EMERGE (NCT03901482)
- Testing
- Dihydroergotamine
- Where
- 117 sites in United States
- Volunteers
- 1,201 people
- Sponsor
- Satsuma Pharmaceuticals, Inc.
Migraine
Migraine Prevention Using ActiPatch
Chronic pain is now widely understood to be due to central sensitization, which leads to exaggerated pain perception. Migraine is no exception, since it is well known that sensitization of the trigeminovascular pain pathway can…
- Trial name
- PSWT (NCT03166046)
- Testing
- Pulsed Shortwave Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- BioElectronics Corporation
Migraine
Aerobic Endurance Training vs. Relaxation Training in Patients With Migraine
This is a single centre, open label, prospective, randomized study on the prophylactic effect of moderate aerobic endurance training versus relaxation training in patients with migraine.
- Trial name
- ARMIG (NCT01407861)
- Testing
- Relaxation Training, Aerobic endurance Training
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Universität Duisburg-Essen
Migraine, Treatment
Facilitators and Barriers to Eptinezumab Administration in Thailand
This research study is designed as a longitudinal prospective descriptive study using mixed-method data collection. Eptinezumab, an anti-calcitonin gene-related peptide monoclonal antibody (anti-CGRP mAb), is administered by…
- Conditions
- Migraine, Treatment, Treatment Refusal
- Trial name
- FACEpi (NCT07035197)
- Testing
- Eptinezumab
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Migraines
A Study of LY2951742 in Healthy Volunteers
To evaluate the safety and tolerability of LY2951742 given as single or multiple subcutaneous injection in healthy male subjects
- Trial name
- NCT01337596
- Testing
- LY2951742
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine, Migraine With Aura
A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess STS101 in the Acute Treatment of Migraine
Study STS101-007 is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to evaluate the efficacy, safety, and tolerability of single doses of STS101 (dihydroergotamine nasal powder) in the acute…
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- SUMMIT (NCT04940390)
- Testing
- Dihydroergotamine
- Where
- 127 sites in United States
- Volunteers
- 1,591 people
- Sponsor
- Satsuma Pharmaceuticals, Inc.
Migraine With Aura, Migraine
The Effect of Connective Tissue Massage in Patients With Migraine
The aim of this study was to investigate the effectiveness of connective tissue massage in patients with migraine
- Conditions
- Migraine With Aura, Migraine, Migraine Without Aura, Connective Tissue Diseases
- Trial name
- NCT04171362
- Testing
- Connective Tissue Massage, Education
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Ankara Yildirim Beyazıt University
Migraine, With or Without Aura
Efficacy, Safety, and Tolerability Study of Oral Ubrogepant in the Acute Treatment of Migraine
This study will evaluate the efficacy, safety, and tolerability of 2 doses of ubrogepant (50 and 100 mg) compared to placebo for the acute treatment of a single migraine attack.
- Trial name
- ACHIEVE I (NCT02828020)
- Testing
- Ubrogepant
- Where
- 90 sites in United States
- Volunteers
- 1,672 people
- Sponsor
- Allergan
Migraine, Chronic Migraine
Neuroimaging Studies of Chronic Primary Headaches Using Positron Emission Tomography and Magnetic Resonance Imaging
Investigators hypothesize that chronic primary headaches are accompanied by a discrete pattern of brain metabolism and activity involving brain structures related to the development of acute exacerbations as well as pain…
- Trial name
- NCT01741246
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Migraine, Headache
Comparison of the Efficacy of Ultrasound-guided Greater Occipital Nerve Block and Pulsed Radiofrequency Therapy in Chronic Migraine Patients
Chronic migraine (CM) is related to headache-related disability and reduced quality of life. Therefore, patients with CM require preventive treatment.
- Trial name
- NCT05464212
- Testing
- USG Guided Greater Occipital Nerve Block, USG Guided Greater Occipital Nerve Block and Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Eskisehir Osmangazi University
Migraine
A Trial to Study of the Effects of Eletriptan 40mg on Mild vs Moderate to Severe Pain Intensity of Migraine
To evaluate the efficacy of early intervention (dosing within 2 hours of onset of the migraine attack) with eletriptan 40mg on mild versus moderate to severe pain intensity of migraine.
- Trial name
- NCT00174395
- Testing
- eletriptan
- Where
- 33 sites in Canada
- Volunteers
- 220 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine, Migraine With or Without Aura
Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency, Intensity, and Functionality: A Single-Arm Study
This research will explore the effect of the Transcendental Meditation® Technique on migraine intensity and frequency. It will be a single-arm pilot study involving 30 participants recruited from migraine treatment facilities and…
- Trial name
- NCT06695156
- Testing
- Meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Maharishi International University
Migraine
Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Attacks In Canada
Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound.
- Trial name
- NCT06692881
- Where
- 13 sites in Canada
- Volunteers
- 178 people
- Sponsor
- AbbVie
Migraine Disorders
A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents With Chronic Migraine
To evaluate the efficacy and safety of Botulinum Toxin Type A versus placebo (normal saline) as headache prophylaxis in adolescents (children 12 to 17) with chronic migraine.
- Trial name
- NCT01662492
- Testing
- Botulinum toxin type A Dose 1, Botulinum toxin type A Dose 2
- Where
- 22 sites in United States
- Volunteers
- 125 people
- Sponsor
- Allergan
"Migraine-like" Headache
Prostaglandin E2 in Migraine Suffers Without Aura.
The hypothesis of this study is that Prostaglandin E2 (PGE2) induces headache and dilatation of brain vessels in migraine patients without aura.
- Trial name
- NCT01384812
- Testing
- dinoprostone, isoton sodium chloride
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Troels Wienecke
Migraine
Inflammatory Markers in Patients With Active Migraine Headaches
The purpose of this study is to determine whether C-Reactive Protein (CRP) is elevated in patients with active migraine headaches.
- Trial name
- NCT00471861
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Westside Family Medical Center, P.C.
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