Clinical trials: Migraine, completed
Migraine, Chronic Migraine
Neuroimaging Studies of Chronic Primary Headaches Using Positron Emission Tomography and Magnetic Resonance Imaging
Investigators hypothesize that chronic primary headaches are accompanied by a discrete pattern of brain metabolism and activity involving brain structures related to the development of acute exacerbations as well as pain…
- Trial name
- NCT01741246
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Acute Migraine
Efficacy and Safety of Acetaminophen and Aspirin Versus Placebo in the Acute Treatment of Migraine
The purpose of the study is to evaluate the efficacy and safety of acetaminophen and aspirin versus placebo in the acute treatment of migraine
- Trial name
- NCT01973205
- Testing
- Acetaminophen 250 mg and Aspirin 250 mg
- Where
- 19 sites in United States
- Volunteers
- 900 people
- Sponsor
- Novartis
Migraine Prophylaxis
Efficacy and Safety Study of E2007 in Migraine Prophylaxis
This was a 22-week, prospective, randomized, double-blind, placebo-controlled, multicenter, parallel-group study that included a 4-week Baseline Phase at the beginning and a 4-week single-blind placebo Safety Phase at the end of…
- Trial name
- NCT00154063
- Testing
- E2007
- Where
- 9 sites in United States
- Volunteers
- 206 people
- Sponsor
- Eisai Inc.
Migraine
Standardized sTudy With Almotriptan in eaRly Treatment of Migraine
This is a observational, open, prospective, single arm cohort study within authorized SPC conditions to describe the effectiveness of Almotriptan in treating acute migraine attacks when pain is mild and in the first hour of pain…
- Trial name
- START (NCT00725140)
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 501 people
- Sponsor
- Almirall, S.A.
Chronic Migraine
Cathodal tDCS in Chronic Migraine: Neurophysiological Study and Pilot Therapeutic Trial
Cathodal tDCS decreases the excitability of the cerebral cortex and its daily application during intercritical phase, may have a therapeutic effect in chronic migraine.
- Trial name
- CATCHROMIG (NCT02122237)
- Testing
- Cefaly tDCS
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- University of Liege
MIGRAINE
Efficacy of Manual Therapy in Migraine
Objective: The aim of this study was to determine the efficacy of suboccipital inhibitory manual therapy treatment in migraine compared to treatment based on Myofascial Trigger Points (MTrPs) and their stretching, often being…
- Trial name
- MTHDIQMi (NCT02446275)
- Testing
- Sternocleidomastoid MTRP and stretching, Trapezius MTRP and stretching
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Valencia
Migraine Headache
Safety & Efficacy of a Single Dose of Sumatriptan Powder Delivered Intranasally With the Bi-directional Device in Adults With Acute Migraine
The study is being conducted to determine if OPTINOSE SUMATRIPTAN delivered nasally (through the nose) using the OPTINOSE SUMATRIPTAN Device can reduce the pain and symptoms associated with migraine headaches.
- Trial name
- NCT01462812
- Testing
- Sumatriptan
- Where
- 15 sites in United States
- Volunteers
- 223 people
- Sponsor
- Optinose US Inc.
Migraine
Oral Dexamethasone for Treatment of Migraine
The aim of this project is to determine if a single dose of oral dexamethasone at the time of discharge from the emergency department (ED) [after successful treatment] prevents rebound headache.
- Trial name
- NCT00216736
- Testing
- Dexamethasone
- Where
- Australia
- Volunteers
- 63 people
- Sponsor
- The Joseph Epstein Centre for Emergency Medicine Research
Migraine Disorders
Topiramate and Cerebrovascular Response in Migraineurs
The purpose of this study is to evaluate the effect of topiramate on cerebrovascular reactivity and mean flow velocity to photic stimulation in migraineurs.
- Trial name
- NCT02424318
- Testing
- Topiramate
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- SMG-SNU Boramae Medical Center
Migraine Disorders, Migraine
Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks
The purpose of this study is to determine the consistency of response for Treximet (sumatriptan/naproxen sodium), formerly known as Trexima, when treating four acute migraine attacks at the mild pain phase and within 1 hour of…
- Trial name
- NCT00240630
- Testing
- sumatriptan succinate/naproxen sodium
- Where
- 50 sites in United States
- Volunteers
- 646 people
- Sponsor
- GlaxoSmithKline
Episodic Migraine
The Effects of Expectation and Knowledge on Rizatriptan and Placebo Treatment of Acute Migraine Headache
Evidence-based medicine depends on distinguishing between pharmacological effects and placebo effects in randomized controlled trials (RCT).
- Trial name
- NCT00719134
- Testing
- Maxalt
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Beth Israel Deaconess Medical Center
Migraine Disorders, Headache
Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Chronic Migraine in Korea
This study is a Post-Marketing Surveillance study in Korea to evaluate the safety and efficacy of botulinum toxin Type A to treat Chronic Migraine in clinical practice.
- Trial name
- NCT01976611
- Testing
- botulinum toxin Type A
- Where
- South Korea
- Volunteers
- 402 people
- Sponsor
- Allergan
Headache, Migraine
Migraine With Aura Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow by Hypoxia
In this study the investigators will investigate the following hypothesis that hypoxia induce migraine headache and migraine aura the aura phase is associated with a spreading reduction in cerebral blood flow the migraine…
- Conditions
- Headache, Migraine, Aura
- Trial name
- NCT01896167
- Testing
- Hypoxia
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Headache, Migraine
Carbon Monoxide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow
In this study the investigators will research the hypothesis that the gas carbon monoxide induces headache and increases the blood flow velocity in the middle cerebral artery.
- Trial name
- NCT02066558
- Testing
- Carbon monoxide
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Cranial Electrotherapy Stimulation in the Treatment of Migraine Headaches
Cranial electrotherapy stimulation (CES) may be a safe adjunct to medical treatment for pain relief in migraine patients. However, despite the number of CES studies done, many have been open label, single blinded, or have…
- Trial name
- NCT01265797
- Testing
- Cranial Electrostimulator
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Toledo Health Science Campus
Migraine Without Aura
PACAP Induced Migraine Attacks in Patients With High and Low Genetic Load
The investigators hypothesized that migraine without patients with many genetic loci associated with migraine (high genetic load) would be more sensitive and get provoked more migraine attacks by PACAP compared to patients with…
- Trial name
- NCT02158221
- Testing
- PACAP
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Danish Headache Center
Migraine
MK3207 for Treatment of Acute Migraines (3207-005)
The purpose of the study is to demonstrate the effectiveness and appropriate dosage level of MK3207 in the treatment of acute migraine.
- Trial name
- NCT00712725
- Testing
- MK3207- 2.5 mg, MK3207- 5 mg, MK3207- 10 mg
- Volunteers
- 676 people
- Sponsor
- Merck Sharp & Dohme LLC
Vestibular Migraine
Comparison of Propranolol and Venlafaxine in Treatment of Vestibular Migraine
The presented study aims to compare effectivity of propranolol with effectivity of venlafaxine in escalating dose in subjects with vestibular migraine (VM) over a period of 12 weeks.
- Trial name
- NCT02350985
- Testing
- Propranolol, Venlafaxine
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Haseki Training and Research Hospital
Migraine Disorders
Chronic Migraine Epidemiology and Outcomes Study
This is a population internet-based study to characterize migraine clinical course and impact on family.
- Trial name
- NCT01648530
- Testing
- No Treatment
- Volunteers
- 16,789 people
- Sponsor
- Allergan
Probable Migraine, Migraine With Aura
Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department
Migraine headaches are a common problem for children. When treatment at home fails, children may benefit from intravenous treatment administered in a hospital setting like the Emergency Department.
- Conditions
- Probable Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- EDMigraine-4 (NCT01596166)
- Testing
- Ketorolac Tromethamine, Metoclopramide
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta