Clinical trials: Migraine Disorders, Brain
Migraine
A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications
The main goal of this trial is to learn whether eptinezumab improves migraine symptoms and quality of life of participants with migraine who did not perceive a sufficient improvement during previous treatment with therapies…
- Trial name
- NCT06701526
- Testing
- Eptinezumab
- Where
- 21 sites in United States
- Volunteers
- 164 people
- Sponsor
- H. Lundbeck A/S
Migraine
Greater Occipital Nerve Block Versus Pulse Radiofrequency in Migraine
The aim of the study is to evaluate the clinical efficacy of the repeated greater occipital nerve(GON) blokcs with GON pulse radiofreaquency (PRF)
- Trial name
- GON-B/PRF (NCT06345326)
- Testing
- Greater occipital nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Adiyaman University Research Hospital
Migraine, With or Without Aura
Long-term Safety of BR005-036C Tablets in the Acute Treatment of Migraine in Adults
The purpose of this study is to evaluate the long-term safety of BR005-036C tablets in the acute treatment of migraines
- Trial name
- NCT07835152
- Testing
- BR005-036C
- Where
- 81 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Brise Pharmaceuticals Co., Ltd.
Migraine With Aura, Migraine Without Aura
Can DFN-15 Terminate Migraine With Allodynia?
The majority of migraineurs seeking secondary or tertiary medical care develop cutaneous allodynia during the course of migraine, a sensory abnormality mediated by sensitization of central trigeminovascular neurons in the spinal…
- Conditions
- Migraine With Aura, Migraine Without Aura, Allodynia
- Trial name
- NCT03472378
- Testing
- DFN-15
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Migraine
Efficacy of OnabotulinumtoxinA in Migraine
Population studies estimate that patients who have episodic migraine transition to chronic migraine at a rate of about 2.5% per year. CM is a devastating disorder associated to severe disability.
- Trial name
- NCT04578782
- Testing
- OnabotulinumtoxinA
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine, Migraine Headache
Neuromodulation During the Prodrome to Prevent Disabling Migraine Attacks in Youth
Background \& Rationale: One in ten Canadian youth have migraine, a disabling neurological disease that is more common in females and characterized by moderate-severe disabling headaches.
- Trial name
- NCT07772427
- Testing
- Active Remote Electrical Neuromodulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Migraine Disorders
Potential Osteocatabolic Effect Caused by Anti-CGRP mAbs in Migraine Patients Treated With Anti-CGRP mAbs - an Observational Pilot Project With Prospectively Collected Health Related Data
Background: To gain insight on the osteoanabolic activity of anti-CGRP mAbs in patients with migraine as this was not yet specifically investigated in registration or post-approval clinical studies, however, being…
- Trial name
- NCT06035458
- Testing
- Diagnostic radiology
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Headache, Migraine
Headache Inducing Effect of NN414 in Migraine Patients
To investigate the role of KATP channels on the cerebral hemodynamic in migraine patients.
- Trial name
- NCT04744129
- Testing
- NN414, Saline
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Danish Headache Center
Migraine, Cluster Headache
Pain Biomarker Study
This study investigates molecular and physical biomarkers of headaches in order to better understand mechanisms of these diseases. There are 3 main parts: 1.
- Conditions
- Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia, Hemicrania Continua
- Trial name
- PBS (NCT03511846)
- Testing
- Oral capsaicin, Topical capsaicin, Intranasal capsaicin
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Migraine, Pain, Shoulder
Effects of MTRPs Therapy in Migraine.
Case series, repeated-measures design, pilot study. Adult, female, migraine patients underwent seven Ischemic Compression Myofascial Trigger Points (IC-MTrPs) therapy sessions.
- Conditions
- Migraine, Pain, Shoulder, Trapezius Muscle Strain Left, Trapezius Muscle Strain Right
- Trial name
- MTRPs (NCT05646160)
- Testing
- Ischemic Compression of Myofascial Trigger Points (IC-MTRPs)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Migraine With Aura, Migraine
The Effect of Connective Tissue Massage in Patients With Migraine
The aim of this study was to investigate the effectiveness of connective tissue massage in patients with migraine
- Conditions
- Migraine With Aura, Migraine, Migraine Without Aura, Connective Tissue Diseases
- Trial name
- NCT04171362
- Testing
- Connective Tissue Massage, Education
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Ankara Yildirim Beyazıt University
Migraine Headaches
Theramine® in the Prevention of Migraine Headache
The purpose of this study is to evaluate the efficacy of Theramine® as a preventative for migraine headaches.
- Trial name
- NCT01944059
- Testing
- Theramine (medical food/old drug)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Vincent Martin, MD
Migraine, Tension-Type Headache
Improved Treatment Course for Patients With Migraine and Tension-type Headache
The purpose of the study is to improve treatment for newly referred patients with migraine and tension-type headache to the Danish Headache Center.
- Trial name
- TeII (NCT05278325)
- Testing
- Telephone intervention
- Where
- Denmark
- Volunteers
- 187 people
- Sponsor
- Danish Headache Center
Migraine
Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines
Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines.
- Trial name
- NCT00122278
- Testing
- Dexamethasone
- Where
- 3 sites in United States
- Volunteers
- 205 people
- Sponsor
- Montefiore Medical Center
Migraine
Mindfulness and Mechanisms of Pain Processing in Adults With Migraines
Although many adults with migraines use non-pharmacological treatment options, there is a lack of research on the use of many mind/body techniques specifically for headache.
- Trial name
- NCT02695498
- Testing
- Mindfulness Based Stress Reduction, Migraine/stress Education
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Wake Forest University Health Sciences
Headache Disorders, Influenza -Like Illness
InfluenCEF Study: Study on the Headache Associated With Influenza Infection
The goal of this observational analytic study with a cohort desing is to evaluate the epidemiology, risk factors and clinical phenotype of headache during Influenza infection.
- Conditions
- Headache Disorders, Influenza -Like Illness, Head Pain, Migraine
- Trial name
- INFLUENCEF (NCT05704335)
- Testing
- Questionnaire administration
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Primary Headache Disorder
Gender Differences and Features of the Clinical Course of Primary Headaches
The pathophysiological mechanisms that underlie primary headache disorders, such as migraine and cluster headache (CH), are complex and not yet fully clarified.
- Trial name
- NCT05760625
- Testing
- analysis BDNF
- Where
- Uzbekistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tashkent Medical Academy
Migraine, Chronic Migraine
Cervical Repositioning Error in Chronic Migraine
This study examines cervical joint position sense in individuals with chronic migraine vs. healthy controls. The ability to reposition the cervical spine after active movement will be evaluated in different head positions.
- Trial name
- NCT05933590
- Testing
- Cervical Joint Repositioning Error Assessment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Acute Migraine
A Study to Learn About the Long-term Safety of Rimegepant for the Acute Treatment of Migraine in Chinese Participants
This trial is to evaluate the long-term safety and tolerability of Rimegepant 75mg ODT in Chinese subjects with migraine
- Trial name
- NCT05371652
- Testing
- Rimegepant 75mg Orally Disintegrating Tablets (ODT)
- Where
- 26 sites in China
- Volunteers
- 241 people
- Sponsor
- Pfizer
Migraine, Hemicrania
Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency
Medication Overuse Headache (MOH) is a disabling condition that affects the 2% of migraine population. Medication overuse (MO) makes this condition very difficult to treat.
- Trial name
- MOHC (NCT04410536)
- Testing
- Symptomatic drugs, Bridge therapy, Mindfulness program
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta