Clinical trials: Migraine Prophylaxis
Migraine
Cabergoline as a Preventive Treatment for Chronic Migraine
Headache disorders constitute a major global disease burden, and migraine - with a one-year prevalence of 15 % - is the sixth most disabling condition. Though a common disease, the pathogenesis is still unclear.
- Trial name
- NCT05525611
- Testing
- Cabergoline 0.5 MG
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Migraine Disorders
Use Of GW274150 In The Prophylactic Treatment Of Migraine
Nitric oxide (NO) is likely to be involved in the development of migraine headache. Nitric oxide synthase (NOS) is an important chemical involved in the production of NO.
- Trial name
- NCT00242866
- Testing
- GW274150
- Where
- 62 sites in Belgium, Denmark and 7 more
- Volunteers
- 430 people
- Sponsor
- GlaxoSmithKline
Migraine Prophylaxis
Effect of Nicotinic Acid as Add on Therapy in Patients Receiving β Blocker for Prophylaxis of Moderate to Severe Migraine
This is a prospective single center, randomized, double-blind, 3 arm placebo-controlled study in subjects with migraine headache requiring prophylactic treatment.
- Trial name
- NCT05846373
- Testing
- Nicotinic Acid 500 MG Extended Release Oral Tablet, Nicotinic Acid 1000 MG Extended Release Oral Tablet
- Where
- Bangladesh
- Volunteers
- 58 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Chronic Migraine
Saline Injections for Prophylactic Treatment of Chronic Migraine
In this study, the investigators want to investigate whether saline injections in the neck and head muscles can reduce symptoms of chronic migraine.
- Trial name
- NCT03919045
- Testing
- Saline injection
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Göteborg University
Migraine, Headache
Long-term Atogepant in Real-world Practice
This prospective multicentre observational study aims to evaluate the long-term effectiveness, safety, tolerability, and treatment persistence of atogepant for migraine prevention in routine clinical practice.
- Conditions
- Migraine, Headache, Headache (Migraine), Migraine Disease
- Trial name
- GEMA PROJECT (NCT07699549)
- Testing
- Atogepant 60 mg, Headache diary, Patient-reported outcome measures
- Where
- Spain
- Volunteers
- 513 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Episodic Migraine
A Study of Eptinezumab in Pediatric Participants With Episodic Migraine
The main goal of this trial is to learn whether eptinezumab helps reduce the number of days with episodic migraine in pediatric participants.
- Trial name
- PROSPECT-1 (NCT05897320)
- Testing
- Eptinezumab
- Where
- 60 sites in United States, Argentina and 9 more
- Volunteers
- 315 people
- Sponsor
- H. Lundbeck A/S
Migraine
A Controlled Trial of Erenumab in Migraine Prevention
The purpose of this study was to assess the efficacy and safety of erenumab for prevention of migraine in Japanese adults with episodic migraine (EM) and chronic migraine (CM).
- Trial name
- NCT03812224
- Testing
- Erenumab
- Where
- 41 sites in Japan
- Volunteers
- 261 people
- Sponsor
- Amgen
Migraine
Medicinal vs. Orthotic Comparison for Migraine Prevention: A Double-Blind Study
To understand the impacts of using a fixed orthotic facial exercise appliance (BLAfit®) for migraine reduction, as compared to medication (fremanezumab-vfrm) and control.
- Trial name
- NCT04547179
- Testing
- Fremanezumab-Vfrm, BLAfit®, Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Manhattan Beach Orthodontics