Clinical trials: Migraine With Aura
Migraine With Aura, Migraine Without Aura
Tailored Digital Treatment for Migraine
Background: An individualized internet-based treatment program from a biopsychosocial perspective has been developed within the Västra Götaland region (VGR) with funds from the Innovation Fund.
- Trial name
- NCT05617339
- Testing
- I am (internet approach to migraine)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Migraine, Migraine With Aura
Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study
The present non-interventional study on migraine prevention with monoclonal CGRP antibodies adresses questions concering safety, swichting from one CGRP mab to another, efficacy on auras in the real world setting.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- NCT05281770
- Testing
- Erenumab, Fremanezumab, Galcanezumab
- Where
- 3 sites in Austria
- Volunteers
- 1,500 people
- Sponsor
- Austrian Migraine Registry Collaboration
Migraine, Classic
Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of Recurrent Migraine
Migraine has been ranked as the second most disabling neurological disorder in the worldwide. Medication or nonpharmacological treatments are all reasonable options for the prevention.
- Trial name
- NCT05516251
- Testing
- Transcutaneous Supraorbital Nerve Stimulator, Topiramate 25Mg Tab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Migraine Without Aura
CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load
The investigators hypothesized that migraine without patients with many genetic loci associated with migraine (high genetic load) would be more sensitive and get provoked more migraine attacks by calcitonin gene-related peptide…
- Trial name
- NCT01924052
- Testing
- CGRP
- Volunteers
- 40 people
- Sponsor
- Danish Headache Center
Migraine Headache, Migraine Without Aura
Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging and Black Blood Imaging MRI
The investigators aim to investigate inflammation of cranial and meningeal arteries during pharmacologically induced migraine attacks, using ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles and black blood imaging…
- Trial name
- NCT02549898
- Testing
- Feraheme, Cilostazol, USPIO-MRI
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Danish Headache Center
Migraine Without Aura
A Randomized Controlled Trial of Acupuncture in Treating Migraine
Migraine without aura is a common kind of nervous system diseases that can easily cause recurrent headache, leading to severe impacts on quality of life and health care costs.
- Trial name
- NCT04766762
- Where
- China
- Volunteers
- 96 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Migraine, Migraine With Aura
A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects
Single-center, single-dose, open-label, 5-period crossover (in each part), pharmacokinetic and safety study.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- NCT05337254
- Testing
- Dihydroergotamine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Satsuma Pharmaceuticals, Inc.
Migraine With Aura, Migraine Without Aura
Optical Coherence Tomography Findings in Migraine
This study aims to detect changes in RNFL thickness in patients with different types of migraine in comparison to healthy control.
- Trial name
- NCT05332431
- Testing
- Optical coherence tomography (OCT)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Migraine Without Aura
Ibuprofen in Migraine Patients
In this study, the investigators planned to compare the effectiveness of an intravenous ibuprofen against an intravenous dexketoprofen among patients (18-65 years) who were admitted to the emergency department (ED) with acute…
- Trial name
- NCT04533568
- Testing
- Ibuprofen 400 mg, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kecioren Education and Training Hospital
Migraine With Aura
Induction of Migraine Aura With Sildenafil
In a double blind placebo-controlled cross-over study the effect of Sildenafil on aura and migraine headache induction is tested in patient with migraine with aura.
- Trial name
- NCT02795351
- Testing
- Sildenafil
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Migraine in Children, Migraine With Aura
Mindfulness for Adolescents for CM and HFEM
Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without Aura affect adolescents' lives in terms of reduced health, reduced ability to perform daily chores and reduced quality of life.
- Trial name
- MINDKIDS (NCT04968093)
- Testing
- Mindfulness-based therapy.
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Occipital Neuralgia, Cervicogenic Headache
Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block
This study will compare the analgesic benefit of a traditional landmark-guided GON block with the ultrasound-guided approach over a four week period in patients with occipital neuralgia or cervicogenic headache.
- Conditions
- Occipital Neuralgia, Cervicogenic Headache, Migraine Without Aura
- Trial name
- NCT03478735
- Testing
- Ultrasound Guided Greater Occipital Nerve Block at C2, Landmark-Based Greater Occipital Nerve Block
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Migraine Without Aura, Migraine With Aura
Evaluation of a Novel Device for Treatment of Migraine Headache
Migraine is a common neurologic with attacks of headache and associated symptoms such as nausea, vomiting, phono and photophobia. Migraine can lead to substantial functional impairment.
- Trial name
- NCT03361423
- Testing
- Nerivio Migra-1 active device
- Where
- 12 sites in United States, Israel
- Volunteers
- 296 people
- Sponsor
- Theranica
Headache Disorders
Assessment of Inflammation in Primary Headaches
Headache is the most common neurological complaint accounting for % 1 to % 4 in the emergency department (ED).Every year, nearly one million people with headache attacks have been consulted by healthcare professionals at the…
- Trial name
- NCT04891848
- Testing
- inflammation
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Migraine With or Without Aura
Low-Dose Naltrexone and Acetaminophen Combination and Its Components in the Acute Treatment of Migraine
The study consists of a screening visit, out-patient treatment of a moderate or severe migraine attack with a single dose of the study medication within 8 weeks, and End-of-Study Visit 2-7 days after dosing.
- Trial name
- ANODYNE-1 (NCT03061734)
- Testing
- Naltrexone and Acetaminophen, Naltrexone and Acetaminophen-High Dose, Naltrexone Alone (regular dose)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Allodynic Therapeutics, Inc
Migraine With and Without Aura
Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute Treatment of Migraine With Nausea
This proof-of-concept study compares side-by-side low-dose naltrexone and acetaminophen combination to sumatriptan in the acute treatment of migraine.
- Trial name
- NCT03185143
- Testing
- Naltrexone and Acetaminophen Combination, Sumatriptan 100 mg
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Allodynic Therapeutics, Inc
Migraine Aura
Interest of the T2 * Sequence in MRI for the Diagnosis of Migraine Aura in the Acute Phase.
investigators hypothesize that T2 * vein abnormalities are frequent and are specific to the migraine aura.
- Trial name
- MARIE (NCT03689361)
- Testing
- MRI, MRI control, telephone consultation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Migraine With or Without Aura
Efficacy, Safety, and Tolerability of Oral Eletriptan for Treatment of Acute Migraine
To confirm the efficacy of three dose levels of oral eletriptan relative to placebo in relieving symptoms of acute migraine and to further explore the dose response relationship of eletriptan.
- Trial name
- NCT01978496
- Testing
- Eletriptan 20 mg, Eletriptan 40 mg, Eletriptan 80 mg
- Volunteers
- 1,334 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine With or Without Aura
Eletriptan vs Sumatriptan: A Double-blind, Placebo-controlled, Multiple Migraine Attack Study
A previously published, placebo-controlled, head-to-head comparator study found eletriptan to have superior efficacy to oral sumatriptan 100 mg in treating a single acute migraine attack.
- Trial name
- NCT01986088
- Testing
- Eletriptan 40 mg, Eletriptan 80 mg, Sumatriptan 50 mg
- Volunteers
- 1,008 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine With or Without Aura
Comparative Study of Oral Eletriptan (40mg and 80mg), Oral Sumatriptan (25mg and 50mg) and Placebo
The objective of this study was to compare the efficacy, toleration and safety of eletriptan 40mg and 80mg, with sumatriptan 25mg and 50mg, and placebo when given orally to subjects with an acute migraine.
- Trial name
- NCT01986270
- Testing
- Eletriptan 40 mg, Eletriptan 80 mg, Sumatriptan 25 mg
- Volunteers
- 1,141 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.