Clinical trials: Migraine With Aura
Migraine Without Aura
Effect of Riocigaut on Migraine Attack Induction in People With Migraine
This double-blind, randomized, placebo-controlled cross-over clinical trial aims to investigate the effects of riocigaut on migraine inducing properties in people with migraine.
- Trial name
- NCT05750446
- Testing
- Riociguat (BAY 63-2521)
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Danish Headache Center
Migraine With Aura, Migraine Without Aura
Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine Headache
The primary objective of this study is to evaluate the efficacy and safety of dronabinol MDI for the acute treatment of moderate to severe migraine headache.
- Trial name
- NCT00123201
- Testing
- Dronabinol MDI
- Where
- 29 sites in United States
- Sponsor
- Solvay Pharmaceuticals
Migraine Headache
Efficacy, Tolerability, and Safety of DFN-15
Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or without aura, being conducted at multiple centers in the United States
- Trial name
- NCT03009019
- Testing
- DFN-15 Active
- Where
- 43 sites in United States
- Volunteers
- 631 people
- Sponsor
- BioDelivery Sciences International
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD
Brief Summary: Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07348783
- Testing
- Intervention yoga based exercises
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Migraine, Migraine Disease
A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department
Prospective, single-site, open-label, non-controlled pilot study consisting of two parallel trials. Participants will receive rimegepant or zavegepant for acute migraine treatment during a single Emergency Department visit, with…
- Conditions
- Migraine, Migraine Disease, Migraine in Adults, Migraine Headache
- Trial name
- NCT07667621
- Testing
- Rimegepant, Zavegepant
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Migraine Disorders
Preventive Role of Melatonin and Propranolol Administration in Pediatric Migraine
This randomized controlled trial evaluated whether adding melatonin to propranolol provided better prevention of migraine in children than propranolol alone.
- Trial name
- NCT07743255
- Testing
- Melatonin, Propranolol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Migraine With Aura, Migraine Without Aura
A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects
Single-center, single-dose, open-label, 2-part, 3-period crossover (in each part), pharmacokinetic and safety study.
- Conditions
- Migraine With Aura, Migraine Without Aura, Migraine
- Trial name
- NCT03874832
- Testing
- Dihydroergotamine
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Satsuma Pharmaceuticals, Inc.
Migraine Disorders
A Study to Determine the Effect of Sumatriptan and Naproxen Sodium Combination Tablet, Sumatriptan Tablet, and Naproxen Sodium Tablet on Blood Pressure When Treating Migraine Headaches That Occur During a 6-month Period
The purpose of this study is to test the effect on blood pressure of sumatriptan and naproxen sodium combination tablets, tablets containing only sumatriptan, and tablets containing only naproxen sodium when these drugs are taken…
- Trial name
- NCT00792636
- Testing
- sumatriptan and naproxen sodium combination tablet, sumatriptan tablet, naproxen sodium tablet
- Where
- 49 sites in United States
- Volunteers
- 407 people
- Sponsor
- GlaxoSmithKline
Migraine
A Clinical Study Examining the Safety and Effectiveness of a New Medication (Keppra®) for the Prevention of Migraine Headaches
The study drug levetiracetam is FDA approved as an add-on medication in the treatment of partial onset seizures in adults with epilepsy. The trade name is Keppra®.
- Trial name
- NCT00203216
- Testing
- levetiracetam, Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Thomas Jefferson University
Emergencies
Brain Perfusion Assessment in the Acute Phase of Migraine Aura
The aim of the study is to determine the proportion of patients with change in brain perfusion during the acute phase of migraine attack with aura.
- Trial name
- PERCAM (NCT03821584)
- Testing
- the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques will have a particular interest
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Nantes University Hospital
Migraine With Aura
Induction of Migraine Aura With Sildenafil
In a double blind placebo-controlled cross-over study the effect of Sildenafil on aura and migraine headache induction is tested in patient with migraine with aura.
- Trial name
- NCT02795351
- Testing
- Sildenafil
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Migraine With Aura, Migraine Without Aura
Investigation of the Blood-brain and Blood-dura Barrier Durin Migraine Attacks Using MRI
Substudy 1 Blood-brain barrier breakdown has been proposed in migraine patients. Our hypothesis that we will test in this study is that the blood-brain barrier breaks down during migraine attacks but not out side attacks using…
- Conditions
- Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- NCT02202486
- Testing
- Brain MRI
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Headache, Migraine Without Aura
Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM)
This study aims to explore the effect of Ivabradine on Levcromakalim-induced migraine in individuals with migraine without aura.
- Trial name
- ILIM (NCT04853797)
- Testing
- Levcromakalim, Ivabradine
- Where
- 2 sites in Denmark
- Volunteers
- 37 people
- Sponsor
- Danish Headache Center
Migraine Headache, With or Without Aura
Staccato Prochlorperazine in Migraine (in Clinic)
Development of Staccato Prochlorperazine for the treatment of migraine headache.
- Trial name
- NCT00610428
- Testing
- Staccato Prochlorperazine 5 mg, Staccato Prochlorperazine 10 mg
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
Basilar Migraine
A Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine
The objective of this study is to assess the long-term safety and effectiveness of topiramate in the prevention of basilar and hemiplegic migraine in children and adolescents.
- Trial name
- NCT00158002
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Monarch Medical Research
Migraine With or Without Aura
Three Doses of Lasmiditan (50 mg, 100 mg and 200 mg) Compared to Placebo in the Acute Treatment of Migraine
This is a prospective randomized, double-blind, placebo-controlled study in participants with disabling migraine (Migraine Disability Assessment (MIDAS) score ≥ 11).
- Trial name
- SPARTAN (NCT02605174)
- Testing
- Lasmiditan 50 mg, Lasmiditan 100 mg, Lasmiditan 200 mg
- Where
- 95 sites in United States
- Volunteers
- 3,005 people
- Sponsor
- Eli Lilly and Company
Migraine Without Aura, Migraine With Aura
Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine
In this study,288 adult migraine patients aged 18-65 years (diagnosed with migraine without aura and/or migraine with aura, with at least a 1-year history)will be collected to evaluate the efficacy, safety and tolerability of…
- Trial name
- ATEM (NCT05416476)
- Testing
- Anisodine Hydrobromide
- Where
- 19 sites in China
- Volunteers
- 288 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Migraine With or Without Aura
Eletriptan vs Sumatriptan: A Double-blind, Placebo-controlled, Multiple Migraine Attack Study
A previously published, placebo-controlled, head-to-head comparator study found eletriptan to have superior efficacy to oral sumatriptan 100 mg in treating a single acute migraine attack.
- Trial name
- NCT01986088
- Testing
- Eletriptan 40 mg, Eletriptan 80 mg, Sumatriptan 50 mg
- Volunteers
- 1,008 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Migraine Without Aura, Acupuncture Therapy
Brain Connectome for Acupuncture-treated Migraine Patients
Acupuncture has been a means of treating headaches and migraine since 2002 and is now a World Health Organisation-recognized prophylactic treatment for migraine.
- Trial name
- ACU-BRAIN (NCT04157192)
- Testing
- Real acupuncture
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes