Clinical trials: Migraine Without Aura
Migraine, Migraine With or Without Aura
Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency, Intensity, and Functionality: A Single-Arm Study
This research will explore the effect of the Transcendental Meditation® Technique on migraine intensity and frequency. It will be a single-arm pilot study involving 30 participants recruited from migraine treatment facilities and…
- Trial name
- NCT06695156
- Testing
- Meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Maharishi International University
Migraine Without Aura, Migraine With Aura
Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
Primary objective: To investigate the efficacy and tolerability of two doses of tonabersat compared to placebo in the prophylaxis of migraine headache and to evaluate the longer term tolerability of tonabersat in an open label…
- Trial name
- TEMPUS (NCT00534560)
- Testing
- Tonabersat
- Volunteers
- 542 people
- Sponsor
- Minster Research Ltd
Migraine, With or Without Aura
Open Label Safety Study in Acute Treatment of Migraine
The purpose of this study is to evaluate safety and tolerability of BHV-3000 (rimegepant).
- Trial name
- NCT03266588
- Testing
- Rimegepant
- Where
- 98 sites in United States
- Volunteers
- 3,019 people
- Sponsor
- Pfizer
Migraine With and Without Aura, Chronic Migraine
Migraine and Body Composition
This research is being done to look at the association between migraine and obesity.
- Conditions
- Migraine With and Without Aura, Chronic Migraine, Healthy Controls
- Trial name
- NCT01720862
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
PFO - Patent Foramen Ovale, Migraine
A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine
Migraine is one of the most common chronic neurological disorders, posing a significant global public health concern. Patent Foramen Ovale (PFO) is the most common congenital heart anomaly in adults.
- Conditions
- PFO - Patent Foramen Ovale, Migraine, Migraine Headache, Migraine Headache, With or Without Aura
- Trial name
- BioMetal (NCT06203873)
- Testing
- Biodegradable occluder, Metal occluder
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Episodic Migraine, Migraine With Aura
Mi-Helper Transnasal Cooling for Acute Treatment of Migraine
This is a prospective, double-blind, sham-controlled, randomized clinical trial . This study aims to assess the efficacy, safety, tolerability, and the optimal dose of the Mi-Helper transnasal cooling device for acute treatment…
- Conditions
- Episodic Migraine, Migraine With Aura, Migraine Without Aura, Migraine
- Trial name
- NCT06051604
- Testing
- Mi-Helper
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- CoolTech LLC
Migraine Disorders, Migraine Without Aura
1H Magnetic Resonance Spectroscopy in Migraine Patients
To investigate the glutaminergic system in the onset of migraine-like attacks.
- Conditions
- Migraine Disorders, Migraine Without Aura, Headache Disorders, Primary, Headache Disorders
- Trial name
- NCT04220606
- Testing
- Glyceryl trinitrate (I.V. infusion 0.5 µg/kg/min over 20 min)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Migraine, Migraine Disorders
Integrative Migraine Pain Alleviation Through Chiropractic Therapy
This pilot study evaluates the addition of chiropractic treatment to conventional neurological care in the treatment of migraine headaches in adult women.
- Conditions
- Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura
- Trial name
- IMPACT (NCT03177616)
- Testing
- Chiropractic Treatment
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Harvard University Faculty of Medicine
Migraine Without Aura, Chronic Tension-Type Headache
Cortical Reorganisation in Patients With Primary Headache Disorders
Primary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased stimulus sensitivity in these patients.
- Trial name
- NCT00263991
- Testing
- EEC-techniques
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine Without Aura, Migraine With Aura
Eletriptan Provides Consistent Migraine Relief: Results Of A Within-Patient Multiple-Dose Study
Evaluation of headache response at 2 hours for active treated attacks for increasing dose.
- Trial name
- NCT01859481
- Testing
- Eletriptan HBr 40 mg, Eletriptan HBr 80 mg
- Where
- 148 sites in Belgium, Czechia and 12 more
- Volunteers
- 971 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine Without Aura
CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load
The investigators hypothesized that migraine without patients with many genetic loci associated with migraine (high genetic load) would be more sensitive and get provoked more migraine attacks by calcitonin gene-related peptide…
- Trial name
- NCT01924052
- Testing
- CGRP
- Volunteers
- 40 people
- Sponsor
- Danish Headache Center
Migraine in Children, Migraine With Aura
Mindfulness for Adolescents for CM and HFEM
Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without Aura affect adolescents' lives in terms of reduced health, reduced ability to perform daily chores and reduced quality of life.
- Trial name
- MINDKIDS (NCT04968093)
- Testing
- Mindfulness-based therapy.
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Pediatric Migraine
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
- Trial name
- NCT04649242
- Testing
- Rimegepant/BHV3000
- Where
- 246 sites in United States, Canada and 7 more
- Volunteers
- 2,100 people
- Sponsor
- Pfizer
Migraine Without Aura, Migraine With Aura
Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
Overall trial objectives: Can treatment with tonabersat reduce the number of days with a migraine headache in patients who suffer from frequent migraine attacks How well tolerated is treatment with tonabersat The study is based…
- Trial name
- NCT00311662
- Testing
- Tonabersat
- Where
- 17 sites in Denmark, Hungary and 2 more
- Volunteers
- 124 people
- Sponsor
- Minster Research Ltd
Migraine
Safety and Efficacy Study of MK0974 in the Acute Migraine (0974-016)
The purpose of this study is to investigate the efficacy and safety of MK0974 compared to a placebo for acute migraine.
- Trial name
- NCT00432237
- Testing
- MK0974 50 mg, MK0974 150 mg, MK0974 300 mg
- Volunteers
- 1,703 people
- Sponsor
- Merck Sharp & Dohme LLC
Migraine Without Aura, Acupuncture
Acupuncture In Migraine Without Aura Patients
The investigators aimed to investigate the effect of acupuncture treatment on attack frequency, pain intensity, and disability in migraine without aura patients who receive prophylaxis treatment.
- Trial name
- NCT04542811
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ataturk University
Migraine, Migraine Without Aura
Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room
The purpose of this study is to evaluate the efficacy of clorazepate in addition to the usual medication for treating migraine attack in the emergency room
- Conditions
- Migraine, Migraine Without Aura, Migraine With Aura, Headache
- Trial name
- CLORMIG (NCT04726592)
- Testing
- Clorazepate Dipotassium, Ketoprofen, Metoclopramide
- Where
- France
- Volunteers
- 323 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine, Classic Migraine
Potential Impact (Benefit) of Preventative Treatment With Topamax on the Effectiveness of Axert in the Acute Treatment of Migraine
The purpose of this study is to evaluate the impact of topiramate (migraine prevention medicine) on the effectiveness of almotriptan malate (acute migraine medicine) when treating acute migraine headaches.
- Conditions
- Migraine, Classic Migraine, Common Migraine
- Trial name
- NCT00210496
- Testing
- topiramate; almotriptan malate
- Volunteers
- 406 people
- Sponsor
- Janssen-Ortho LLC
Headache, Migraine With Aura
The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain.
The aim of the present study to investigate whether Opening of KATP channels causes migraine pain by activation of meningeal nociceptors and ascending trigeminal nociceptive pathways.
- Conditions
- Headache, Migraine With Aura, Migraine Without Aura
- Trial name
- NCT05565001
- Testing
- Levcromakalim
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Danish Headache Center
Migraine
A Study to Test the Safety and Effectiveness of MK-0974 (Telcagepant) Co-administered With Ibuprofen or Acetaminophen in Patients With Migraines With or Without Aura (MK-0974-046)
This study will test the safety and how effective telcagepant is when taken with ibuprofen or acetaminophen in participants with migraine with or without aura.
- Trial name
- NCT00758836
- Testing
- ibuprofen, acetominophen, telcagepant
- Volunteers
- 683 people
- Sponsor
- Merck Sharp & Dohme LLC