Clinical trials: Mild Cognitive Impairment
Mild Cognitive Impairment, Dementia
Short-term Automated Longitudinal Analysis of Speech and Language in Cognitive Impairment
Validate speech analysis AI models: To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia.
- Trial name
- NCT05340218
- Testing
- Speech analysis
- Where
- Spain
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Accexible
Cognitive Impairment, Alzheimer Disease, Early Onset
Juice Plus Supplement Clinical Trial
The study is designed to determine whether encapsulated fruit and vegetable juice concentrates can improve biological indicators of cognitive and multiple dimensions of memory and learning.
- Conditions
- Cognitive Impairment, Alzheimer Disease, Early Onset, Mild Cognitive Impairment
- Trial name
- NCT04656860
- Testing
- Juice Plus+
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Dementia With Lewy Bodies, Alzheimer Disease
DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia
This a study to improve diagnosis of dementia with Lewy bodies with RT-QuIC in different biospecimens.
- Conditions
- Dementia With Lewy Bodies, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- DISPLAY (NCT05768425)
- Testing
- Real-time quaking-induced conversion (RT-QuIC), Cognitive test, Motor examination
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Danish Dementia Research Centre
Mild Cognitive Impairment, Alzheimer's Disease
Investigating the Clinical Consequences of Flutemetamol-PET-scanning
The study examines subjects where there might be an indication for Amyloid-PET according to the Criteria defined by the Amyloid Imaging Task Force.
- Conditions
- Mild Cognitive Impairment, Alzheimer's Disease, Dementia
- Trial name
- NCT02353949
- Testing
- Flutemetamol (Vizamyl)
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University of Zurich
Mild Cognitive Impairment
Reshaping the Path of Mild Cognitive Impairment by Refining Exercise Prescription
Dementia is one of the most pressing health care issues of the 21st century. Evidence suggests that exercise enhances cognitive function in healthy older adults. Most research has focused on aerobic training (AT).
- Trial name
- NCT02737878
- Testing
- Aerobic Training, Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 226 people
- Sponsor
- University of British Columbia
Mild Cognitive Impairment
Cognitive Training in Patients With MCI Using fMRI
The current project aims to investigate the trajectories of the visual imaging cognitive training (CT) and alphabet search training using fMRI in patients with amnestic mild cognitive impairment (MCI) and healthy elderly controls…
- Trial name
- NCT03263247
- Testing
- Visual Memory Training, Alphabet search
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Parkinson's Disease, Mild Cognitive Impairment
A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease
This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving training compared to supportive therapy in individuals with Parkinson's Disease with Mild Cognitive Impairment (MCI) and their support…
- Trial name
- NCT01646333
- Testing
- Memory and Problem-Solving Intervention, Supportive Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Virginia Commonwealth University
Mild Cognitive Impairment, Poor Quality Sleep
Hypnosis for Sleep Quality for Individuals With Mild Cognitive Impairment
With the long-range goal to identify an efficacious and practical intervention to improve sleep for individuals with MCI, this pilot study will enroll 20 individuals with MCI into either a self-administered hypnosis for sleep…
- Trial name
- NCT05215717
- Testing
- Self-Administered Hypnosis, Self-Administered White Noise Hypnosis
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor University
Alzheimer's Disease, Mild Cognitive Impairment
Preliminary Study of Fish Oil and Dementia
This preliminary study is aimed to investigate whether it is feasible to conduct a study to use fish oil compared to the placebo(olive oil) in people with cognitive impairment.
- Trial name
- NCT00628017
- Testing
- omega-3 polyunsaturated fatty acids ( EPA+DHA)
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Taipei City Psychiatric Center, Taiwan
Alzheimer Disease, Mild Cognitive Impairment
Software Validation Study-Cognitive Status Indicator
The SPARK Cognitive Status Indicator software uses an algorithm to assess a resting state EEG recording as being consistent with a cognitive status of unimpaired, mild cognitive impairment (MCI; MCI AD- or MCI AD+), or dementia…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia
- Trial name
- REMIND-V (NCT06809725)
- Testing
- SPARK Cognitive Status Indicator (software support data collected via EEG)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Spark Neuro Inc.
Alzheimer Disease, Mild Cognitive Impairment
Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Previous studies found that some NMDA-enhancing agents were able to improve cognitive function of patients with early-phase dementia.
- Trial name
- NCT06467539
- Testing
- DAOIB plus AO
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Technology
Therapeutic Effectiveness of PARO Companion Robot for Elderly With Mild Cognitive Impairment/Dementia in Elderly Residential Setting: A Quasi-experimental Study
The main trial is a 2-group quasi-experimental trial of comparing the outcome indicators between joining and not joining the 10-week personal assistive robot (PARO) training program in residents with dementia or mild cognitive…
- Trial name
- NCT05404802
- Testing
- Experimental group intervention, Control group intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 37 people
- Sponsor
- The University of Hong Kong
Cognitive Impairment, Mild Cognitive Impairment
Assessing Performance on Speech Tasks Via Crowdsourced Participants
The purpose of the study is to examine the properties of the Automatic Story Recall Test (ASRT) and its parallel variants, as well as letter fluency and category fluency cognitive tests.
- Trial name
- AMYWEB (NCT05298501)
- Testing
- No intervention/exposure
- Where
- United Kingdom
- Volunteers
- 1,034 people
- Sponsor
- Novoic Limited
Alzheimer's Disease, Mild Cognitive Impairment
Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly
The primary objective is to examine the efficacy of 8-weeks of a locally developed brain-computer interface based system (BrainpalTM)intervention for improving attention and memory in normal elderly.
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Cognitive Decline, Dementia
- Trial name
- 3ECog (NCT01661894)
- Testing
- BrainPalTM
- Where
- Singapore
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Dementia (Diagnosis), Mild Cognitive Impairment
Choose Myself (Before) Losing Myself
The purpose of this study is to see if an educational interactive booklet about how dementia progresses throughout a person's life can be a helpful tool for patients to think about future decisions that might need to be made…
- Conditions
- Dementia (Diagnosis), Mild Cognitive Impairment, Alzheimer's Disease Dementia, Alzheimer's Disease
- Trial name
- CYOA (NCT07846566)
- Testing
- CYOA booklet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Mild Cognitive Impairment
The Relationship Between Metamemory and Memory in Old Age
The purpose of this research is to explore the relationship of metamemory and memory of elders and to evaluate the effectiveness of a metamemory cognitive intervention on elders with mild cognitive impairment and low memory…
- Trial name
- M&Mresearch (NCT02113345)
- Testing
- Metamemory Cognitive Intervention
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Alzheimer Disease, Mild Cognitive Impairment
Memory Enhancement Using Transcranial Alternating Current Stimulation
The 32 million Alzheimer's disease (AD) and 69 million prodromal AD patients worldwide contribute to a large economic burden. Effective and safe therapies that slow or prevent the progression from mild cognitive impairment (MCI)…
- Trial name
- Memento (NCT06202872)
- Testing
- Gamma (40 Hz) tACS at the precuneus region
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Amsterdam UMC, location VUmc
Alzheimer Disease, Dementia
ANNE Vital Sign System Remote Sleep Assessment
Sleep apnea is characterized by temporary pauses or stops to participant's breathing. Currently, sleep apnea is diagnosed using an in-lab sleep study, which involves spending a night in a sleep laboratory hooked up to wires on…
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment, Sleep Apnea
- Trial name
- NCT05669495
- Testing
- ANNE Vital Sign System
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Parkinson&Amp;Amp;#39;s Disease (PD)
Mid-frontal Delta/Theta and Cognitive Control
Abstract Cognitive symptoms of Parkinson's disease (PD) include deficits in attention, working memory, and reasoning. These deficits affect up to 80% of PD patients and lead to mild cognitive impairment (PD-MCI) and dementia in…
- Trial name
- NCT06984757
- Testing
- Deep-brain Stimulation, Transcranial Magnetic Stimulation, Transcranial Alternating Current Stimulation
- Where
- United States
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Nandakumar Narayanan
Mild Cognitive Impairment
ThinkingFit: Combined Physical, Cognitive and Social Treatment in Mild Cognitive Impairment (MCI)
Dementia is serious problem and around 700 000 people are affected in the UK alone. Currently there is no cure however early diagnosis and effective treatment offers hope for reducing the impact.
- Trial name
- ThinkingFit (NCT01603862)
- Testing
- ThinkingFit programme
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- Dr Thomas Dannhauser