Clinical trials: Mild Depression, open to volunteers
Depression, Mild Traumatic Brain Injury
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans…
- Conditions
- Depression, Mild Traumatic Brain Injury, Concussion, Brain
- Trial name
- NCT05682677
- Testing
- iTBS, Personalized, Augmented Cognitive Training (PACT)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, San Diego
Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS)
Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study
This is a randomized, controlled study. ACS follow- up patients aged 18 to 80 years old with hemodynamic stability, who are 14 days to 1 year after PCI, are screened through the HAMD score and the HAMA score.
- Conditions
- Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS), Percutaneous Coronary Intervention (PCI), Depressive Disorder
- Trial name
- NCT07454070
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jing Han
Mild Cognitive Impairment (MCI), Depressive Symptoms
rTMS Combined With Aerobic Exercise for Older Adults With Mild Cognitive Impairment and Comorbid Depression
This study aims to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) and aerobic exercise on cognitive function and mental health in older adults with mild cognitive impairment (MCI) and comorbid…
- Trial name
- NCT07652775
- Testing
- Repetitive Transcranial Magnetic Stimulation, Aerobic Exercise
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Cheng-Hsin General Hospital
Mild-to-moderate Depression, Neural Activity
Probiotics for Depressive Symptomatology and Neural Activity.
This study aims to investigate the acute and chronic effects of 16-week probiotic supplementation (Ecologic® Barrier) on depressive symptoms and neural activity in those with mild-to-moderate depression.
- Conditions
- Mild-to-moderate Depression, Neural Activity, Executive Function (Cognition)
- Trial name
- PRODAN (NCT07667530)
- Testing
- Ecologic® Barrier
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University of Reading
Mild to Moderate Depressive Symptoms
Online Self-healing Program
Background. Almost two thirds of adolescents experience a mental disorder before the age of 25. Among mental disorders, depression is one of the most common among young people aged between 15 to 24, with a prevalence of 13.5% to…
- Trial name
- iCBT-A (NCT07374653)
- Testing
- Online Cognitive Behaviural Therapy, Online Relaxation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Depression and/or Anxiety in the Mild-to-moderate Range, Stress (Psychology)
SanaMente: A Peer-Led Program to Reduce Health Disparities in Rural Latino/a Communities
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of the SanaMente peer-led mental health and lifestyle program for rural Latino/a adults with chronic medical conditions…
- Conditions
- Depression and/or Anxiety in the Mild-to-moderate Range, Stress (Psychology), Chronic Medical Illness
- Trial name
- SanaMente (NCT07705776)
- Testing
- SanaMente
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Mild Cognitive Impairment in Middle-aged Adults
Deafness and Cognition in Middle-aged Adults
A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years.
- Trial name
- SURDICOG (NCT05149742)
- Testing
- Cognitive and audiometry evaluation
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness
Social Prescribing for a Mindful Lifestyle
The goal of this clinical trial is to evaluate the effectiveness of an 8-week mindfulness lifestyle social prescribing program in community-dwelling older adults aged 55 and older.
- Conditions
- Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness, Social Isolation
- Trial name
- NCT07669805
- Testing
- Mindfulness Lifestyle Social Prescribing Program
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Depressive Disorder
PB-18 Probiotic for Mild to Moderate Depression
The goal of this clinical trial is to learn if Bifidobacterium PB-18 can treat mild to moderate depressive disorder in adults aged 18 to 65 years who are not taking antidepressants or other psychotropic medications during the…
- Trial name
- NCT07562516
- Testing
- Bifidobacterium
- Volunteers
- 88 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder
Ketamine Treatment for PTSD and MDD in TBI
The goal of this clinical trial is to examine the use of sedative ketamine to treat depression and post-traumatic stress disorder (PTSD) in Veterans with mild to moderate traumatic brain injury (TBI).
- Conditions
- PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder, Traumatic Brain Injury
- Trial name
- NCT06228391
- Testing
- IV ketamine, Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Mild Cognitive Impairment, Cognitive Function
Binaural Beats for Cognitive Function in Older Adults With Mild Cognitive Impairment in Nursing Homes
This study will evaluate whether binaural beats can improve cognitive function in older adults with mild cognitive impairment living in nursing homes.
- Trial name
- BB-MCI (NCT07735910)
- Testing
- Binaural Beats Embedded in Old Songs, Old Songs
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- China Medical University, China