Clinical trials: Mild Hypertension
Chronic Thromboembolic Disease
BPA in CTEPD Without PH
The goal of this clinical trial is to assess the effect of Balloon Pulmonary Angioplasty (BPA) on quality of life and exercise capacity in patients with chronic tromboembolic pulmonary disease (CTEPD) without pulmonary…
- Trial name
- BALLOON (NCT06090838)
- Testing
- Balloon Pulmonary Angioplasty (BPA)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypertension, Grade 1, Hypertension Treatment
Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril
The purpose of this trial is to evaluate if an objective clinical decision of anti-hypertensive therapy can be made using an N-of-1 (single patient) trial design.
- Conditions
- Hypertension, Grade 1, Hypertension Treatment, N of 1 Study Design, Hypertension
- Trial name
- 1HAT (NCT01258764)
- Testing
- Lisinopril, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Scripps Translational Science Institute
Essential Hypertension
Effect of Acupuncture on Patients With Mild Hypertension
This is a large scale, open-label, multicenter, randomized controlled clinical trial with four parallel arms. This trial aims to evaluate the effectiveness of affected meridian acupuncture for patients with mild hypertension,with…
- Trial name
- EAPMH (NCT01701726)
- Testing
- acupuncture
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Mild Autonomous Cortisol Secretion (MACS)
Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)
To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Isturisa will exhibit significantly better metabolic indicators (such as…
- Trial name
- NCT07247058
- Testing
- Osilodrostat (Isturisa)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Hypertension
Effects of Peppermint Oil in Mild-moderate Hypertension.
Cardiovascular and associated hypertensive diseases are the leading health burden and cause of mortality worldwide; therefore, the necessity for effective interventions is paramount.
- Trial name
- NCT05561543
- Testing
- Peppermint oil
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Central Lancashire
Hypertension
Irbesartan/Hydrochlorothiazide and Irbesartan in the Treatment of Mild to Moderate Hypertension
Study Objectives : To demonstrate the reduction in office Blood Pressure following a 8-week regimen of irbesartan / hydrochlorothiazide using irbesartan as a reference.
- Trial name
- NCT00263003
- Testing
- Irbesartan/hydrochlorothiazide, Irbesartan
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Sanofi
Essential Hypertension
NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial
In this Phase III clinical trial, researchers evaluate the efficacy and safety of NW Roselle®, a powdered medicinal product developed by Natural Wellness.
- Trial name
- NCT06141200
- Testing
- NW Roselle, Captopril 25Mg Tab
- Volunteers
- 286 people
- Sponsor
- Natural Wellness Egypt
Hypertension
Telmisartan Compared to Losartan + Hydrochlorothiazide in Patients With Mild-to-moderate Essential Hypertension
The general aim and clinical objective of this trial is to determine the effect of telmisartan 80 mg compared to losartan 50 mg + HCTZ (Hydrochlorothiazide) 12.5 mg on reduction of blood pressure (BP) in patients with mild to…
- Trial name
- NCT02183701
- Testing
- Telmisartan, Losartan + Hydrochlorothiazide
- Volunteers
- 715 people
- Sponsor
- Boehringer Ingelheim
Hypertension
The Effects on Blood Pressure Control, Pulse Wave Velocity, as Well as Safety and Tolerability of Felodipine Sustained Release in Chinese Patients.
The purpose of this study is to evaluate the effects on blood pressure control, pulse wave velocity, as well as safety and tolerability of felodipine single or combine with other drugs in Chinese Hypertension patients.
- Trial name
- NCT02336607
- Testing
- Felodipine tablet (Plendil) alone, Felodipine tablet (Plendil)+Hydrochlorothiazide, Felodipine tablet (Plendil)+Metoprolol tablet (Betaloc ZOK)
- Volunteers
- 529 people
- Sponsor
- AstraZeneca
Hypertension
A Study To Evaluate The Efficacy Of Eplerenone Compared With Losartan For The Treatment Of Patients With Mild To Moderate Hypertension
The purpose this study is to compare the efficacy of eplereonone and losartan in patients with mild to moderate hypertension.
- Trial name
- NCT00649311
- Testing
- eplerenone, Losartan
- Where
- 2 sites in Taiwan
- Volunteers
- 248 people
- Sponsor
- Pfizer
Hypertension
PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)
To demonstrate that Telmisartan combined with Hydrochlorothiazide (MICARDIS® HCT) is superior to Losartan with Hydrochlorothiazide (Hyzaar®) in lowering blood pressure in mild-moderate hypertensives.
- Trial name
- NCT00274638
- Testing
- Telmisartan & Hydrochlorothiazide, Losartan & Hydrochlorothiazide, ABPM
- Where
- 69 sites in United States
- Volunteers
- 805 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Anti-hypertensive Effect of Mycelia of Antrodia Cinnamomea
This the first report undertaken to assess the effect of supplementation with oral gamma-aminobutyric acid (GABA), adenosine and antrosterol-containing AC mycelia on blood pressure among people with mild hypertension.
- Trial name
- NCT02532699
- Testing
- AC mycelia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Hypertension, Prehypertension
Effects and Safety of Menthol on Blood Pressure and Metabolic Parameters in Prehypertensive and Mild Hypertensive Patients
Prehypertension and mild hypertension are associated with an increased risk of atherosclerosis and coronary artery disease, and often complicated with the metabolic disorder of glucose and lipid.
- Trial name
- ESMAB (NCT01408446)
- Testing
- Menthol
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zhiming Zhu
Hypertension
Study of IBI3016 in People With Mild or Moderate Hypertension Patients
A Phase I clinical study evaluating the safety, tolerability, pharmacokinetic characteristics, and pharmacodynamic characteristics of a single subcutaneous dose of IBI3016 in Chinese patients with mild to moderate hypertension.
- Trial name
- NCT07556796
- Testing
- IBI3016
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Primary Mild and Moderate Hypertension
Study on Human Mass Balance of SPH3127 Tablets
To quantitatively analyze the total radioactivity in the excreta of healthy male subjects after oral administration of [14C] SPH3127, and determine the cumulative excretion rate and main excretion routes of radioactive…
- Trial name
- NCT05593562
- Testing
- SPH3127
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shanghai Pharmaceuticals Holding Co., Ltd
Pre-Eclampsia; Mild
Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
Mild pre-eclampsia represents 75% of cases with pre-eclampsia, possible progression to severe pre-eclampsia makes mild pre-eclampsia a serious problem that requires attention.
- Trial name
- NCT03262961
- Testing
- Sildenafil 20 MG
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Preeclampsia and Eclampsia, Preeclampsia Severe
Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification
The purpose of this study is to 1. Identify a cut-off for the ratio of the serum proteins soluble FMS-like Tyrosine Kinase 1 (sFLT-1) and placental growth factor (PlGF) that identifies women will who develop preeclampsia with…
- Conditions
- Preeclampsia and Eclampsia, Preeclampsia Severe, Gestational Hypertension, Chronic Hypertension in Obstetric Context
- Trial name
- PRAECIS (NCT03815110)
- Where
- 18 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- Cedars-Sinai Medical Center
Hypertension, Blood Pressure
Morning Versus Bedtime Dosing of Antihypertensive Medication
Previous studies have shown that elevated nighttime blood pressure (BP) was more closely associated with cardiovascular mortality and morbidity than daytime and clinic BPs.
- Conditions
- Hypertension, Blood Pressure, Drug Use
- Trial name
- NCT05089448
- Testing
- Alisartan, Amlodipine besylate
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Yan Li
Refractory Hypertension
Renal Sympathetic Denervation in Mild Refractory Hypertension
The purpose of this study is to examine the benefit of renal sympathetic denervation in patients with mild refractory hypertension
- Trial name
- NCT01656096
- Testing
- Renal sympathetic denervation (Symplicity ablation catheter, Medtronic Inc. Minneapolis, Minnesota, USA)
- Where
- Germany
- Volunteers
- 71 people
- Sponsor
- University of Leipzig
Menopause, Hypertension
Non-Comparative Study To Evaluate Changes In FMD After Quinapril Therapy In Hypertensive Women
ACE inhibitors are thought to modify the endothelium in a number of ways. Quinapril is an effective and well-tolerated ACE-I for the treatment of patients with hypertension and congestive heart failure.
- Trial name
- NCT00147524
- Testing
- quinapril, Laser Doppler imaging
- Where
- 5 sites in Hungary
- Volunteers
- 70 people
- Sponsor
- Pfizer