Clinical trials: Mild Obstructive Sleep Apnea, active
Obstructive Sleep Apnea, Mild Cognitive Impairment
Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment
Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and leads to cardiometabolic and neurocognitive…
- Conditions
- Obstructive Sleep Apnea, Mild Cognitive Impairment, Subjective Cognitive Impairment
- Trial name
- NCT06089096
- Testing
- Home Sleep Apnea test (HSAT)
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea
Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index
The purpose of the study is to compare the relative contribution of systemic inflammation vs. Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting cardiovascular and metabolic aberrations…
- Trial name
- NCT03062748
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Milton S. Hershey Medical Center
Mild Cognitive Impairment, Sleep Apnea, Obstructive
MCI: CPAP Treatment of OSA (Memories2)
The purpose of this project is to determine whether obstructive sleep apnea (OSA) treatment with positive airway pressure therapy (CPAP) can delay the progression of cognitive impairment in patients with amnestic Mild Cognitive…
- Trial name
- MCI:OSA (NCT03113461)
- Testing
- CPAP
- Where
- 4 sites in United States
- Volunteers
- 327 people
- Sponsor
- University of Pennsylvania
Sleep Apnea, Chronic Nasal Congestion
Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
The addition of intranasal oxymetazoline for two weeks to already instituted optimal doses of intranasal fluticasone propionate will decrease the total number of obstructive apneas and hypopneas per hour of sleep in subjects with…
- Trial name
- NCT02630121
- Testing
- Oxymetazoline Hydrochloride
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of South Florida
Snoring, OSA - Obstructive Sleep Apnea
Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).
This clinical investigation is a prospective, non-randomized, parallel-group clinical investigation conducted at two (2) investigative sites.
- Trial name
- NCT07613281
- Testing
- Palatal Implant System
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Serene Sleep, Inc.
Adenotonsillectomy, Obstructive Sleep Apnea (OSA)
Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea
Emphasize that the usage of multimodal analgesia in managing perioperative pain in children with mild to moderate Obstructive Sleep Apnea undergoing adenotonsillectomy may achieve the same efficacy of fentanyl with less…
- Conditions
- Adenotonsillectomy, Obstructive Sleep Apnea (OSA), Fentanyl, Opioid
- Trial name
- NCT07435493
- Testing
- Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Mild Cognitive Impairment, Obstructive Sleep Apnea
Evaluation of Trazodone in OSA-MCI
Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disease. Before progressing to AD, individuals may experience mild cognitive impairment (MCI).
- Trial name
- NCT05209035
- Testing
- Trazodone
- Where
- Hong Kong
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment
CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial
Obstructive sleep apnea (OSA) is a prevalent condition that significantly impacts the sleep health and overall well-being of millions of adults worldwide.
- Trial name
- CRESCENDO (NCT06983769)
- Testing
- MAD, CPAP
- Where
- Singapore
- Volunteers
- 260 people
- Sponsor
- National University Hospital, Singapore
Sleep Apnea, Obstructive, Snoring
Different Forms of OMT as Methods for Reducing Snoring and Mild to Moderate Sleep Apnea
Objective the present project aims to assess the impact of 1) oral screen training, group training, and the use of neuromuscular electrical training (NMES) as orofacial myofunctional therapy (OMT) methods for reducing the…
- Trial name
- SNORT (NCT06330116)
- Testing
- IQoro, eXciteosa, Grouptraining
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 141 people
- Sponsor
- Region Västerbotten
Obstructive Sleep Apnea, Mild Cognitive Impairment
Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment
Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and potentially lead to cardiometabolic and…
- Conditions
- Obstructive Sleep Apnea, Mild Cognitive Impairment, Subjective Cognitive Impairment
- Trial name
- NCT06150352
- Testing
- Continuous Positive Airway Pressure or other management for OSA per clinical indications.
- Where
- Hong Kong
- Volunteers
- 180 people
- Sponsor
- The University of Hong Kong
Sleep Apnea, Obstructive
Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea
It is unknown whether passive myofunctional appliances can be used for the treatment of obstructive sleep apnea and snoring, nor how to select the appropriate size per individual patient.
- Trial name
- NCT05497180
- Testing
- passive myofunctional appliance, standard oral appliance
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea, Alzheimer Disease
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in…
- Conditions
- Obstructive Sleep Apnea, Alzheimer Disease, Vascular Dementia, Mild Cognitive Impairment
- Trial name
- ENCHANT (NCT04335994)
- Testing
- In-laboratory polysomnography, Home Sleep Apnea Test
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Mild Obstructive Sleep Apnea, Snoring
Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.
Snoring is a common problem caused by vibration of tissues in the throat region during sleep. Although snoring is sometimes dismissed as a minor nuisance rather than a medical disorder, several studies indicate that snoring can…
- Trial name
- MTASSA (NCT06587256)
- Testing
- Mouth Tape
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea
Orofacial Myofunctional Therapy and Positive Airway Pressure-CPAP Trial for Mild-to-Moderate Obstructive Sleep Apnea
The goal of this clinical trial is to evaluate the isolated and combined effects of orofacial myofunctional therapy (OMT) and continuous positive airway pressure (CPAP) in adults with mild-to-moderate obstructive sleep apnea.
- Trial name
- OMPACT-OSA (NCT07539870)
- Testing
- Orofacial Myofunctional Therapy, Continuous Positive Airway Pressure, Standard of Care Sleep-Hygiene and Lifestyle Counseling
- Volunteers
- 168 people
- Sponsor
- Saint-Joseph University
Apnea, Obstructive Sleep, Obstructive Sleep Apnea
OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA).
- Trial name
- OSA-18 (NCT05911646)
- Testing
- OSA-18 Survey, Decisional Conflict (DCS)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Mild Cognitive Impairment (MCI)
Effect of Intranasal Negative Pressure Therapy on Cognitive Function in Patients With Mild Cognitive Impairment and Obstructive Sleep Apnea
This study is a randomized controlled trial with two phases: pre-trial and formal trial. The pre-trial will include 5 participants to observe the 4-week adherence (≥4 hours/night) and safety (adverse event rate) of the iNAP…
- Trial name
- NCT07353359
- Testing
- Intranasal Negative Pressure
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Xuanwu Hospital, Beijing
Obstructive Sleep Apnea
OROPHARYNGEAL MYOFUNCTIONAL THERAPY IN OBSTRUCTIVE SLEEP APNEA
Obstructive Sleep Apnea (OSA) is a prevalent nocturnal breathing disorder among the general population. Oropharyngeal myofunctional therapy (OMT) is an alternative conservative treatment used to improve OSA, associated health…
- Trial name
- NCT06681974
- Testing
- CONTROL:Information form with hygienic-dietary measures or sleep hygiene guidelines is provided and explained., EXPERIMENTAL: program of exercises that will be composed of 4 blocks
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Sleep-disordered Breathing (SDB), Idiopathic Scoliosis
Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing
This study aims to determine the effect of adenotonsillectomy (AT) surgery on the progression of spinal curvature in children with mild sleep-disordered breathing (SDB) and concurrent scoliosis, as well as its potential role in…
- Conditions
- Sleep-disordered Breathing (SDB), Idiopathic Scoliosis, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07332780
- Testing
- Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting with Supportive Care
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI)
CPAP Randomized Controlled Trial
The overall goal of this randomized controlled trial is to test the hypothesis that in older adults with mild cognitive impairment (MCI) and previously untreated obstructive sleep apnea (OSA), 4 months of web-based sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI), Cognitive Decline Prevention in Pre-frail Older Adults
- Trial name
- NCT06773416
- Testing
- CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health, Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Sunnybrook Health Sciences Centre