Clinical trials: Mild to Moderate COVID-19
COVID-19
A Safety, Tolerability, and Efficacy Study of IBI314 in Patients With Mild to Moderate COVID-19
This is a Phase 1/2 study evaluating the safety, tolerability and efficacy of IBI314.
- Trial name
- NCT05172141
- Testing
- IBI314(low dose), IBI314(high dose), IBI314(medium dose)
- Where
- China
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Coronavirus Disease 2019
Study to Evaluate the Efficacy and Safety of Leronlimab for Mild to Moderate COVID-19
This is a Phase 2, two-arm, randomized, double blind, placebo controlled multicenter study to evaluate the safety and efficacy of leronlimab (PRO 140) in patients with mild-to-moderate symptoms of respiratory illness caused by…
- Trial name
- NCT04343651
- Testing
- Leronlimab (700mg)
- Where
- 12 sites in United States
- Volunteers
- 86 people
- Sponsor
- CytoDyn, Inc.
COVID-19 Respiratory Infection
Ketotifen and Indomethacin Combination Treatment Clinical Trial for COVID-19
The purpose of this study is to evaluate the safety and effectiveness of ketotifen and indomethacin taken together to improve symptoms related with COVID-19.
- Trial name
- KICC COVID-19 (NCT05007522)
- Testing
- Ketotifen/Indomethacin
- Where
- 2 sites in Nepal
- Volunteers
- 150 people
- Sponsor
- Sen-Jam Pharmaceutical
SARS-CoV Infection
Efficacy and Safety of Ozonised Oil (HOO) in COVID-19 Patients
The anti-viral efficacy of ozone against RNA viruses is already established. Ozone gas have been already proposed as possible therapy for Covid-19 infection with insofar limited success.
- Trial name
- HOO-COVID (NCT04651387)
- Testing
- Ozonized oil (HOO
- Sponsor
- Neuromed IRCCS
Mild-to-moderate COVID-19
Clinical Trial for Oral Formula of Vanillin and Wheat Germ Oil for Treatment of Mild and Moderate COVID-19 Viral Disease
The study is a randomized clinical trial to assess a natural formula of vanillin \& wheat germ oil to treat and stop the clinical progression of COVID-19.
- Trial name
- NCT05157139
- Testing
- Oral Capsule
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Coronavirus Infections, Pneumonia, Viral
Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19
The scientific community is in search for novel therapies that can help to face the ongoing epidemics of novel Coronavirus (SARS-Cov-2) originated in China in December 2019.
- Conditions
- Coronavirus Infections, Pneumonia, Viral, Acute Respiratory Distress Syndrome
- Trial name
- NoCovid (NCT04305457)
- Testing
- Nitric Oxide
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Massachusetts General Hospital
COVID-19, Hypoxemia
iNOPulse for COVID-19
This randomized, controlled trial will assess the efficacy and safety of pulsed iNO in subjects with COVID-19 who are hospitalized and require supplemental oxygen.
- Conditions
- COVID-19, Hypoxemia, Hypoxemic Respiratory Failure
- Trial name
- NO-COVER (NCT04398290)
- Testing
- Inhaled nitric oxide (iNO), Nitrogen gas, Oxygen gas
- Where
- United States
- Sponsor
- Roger Alvarez
Covid19, CBD
Synthetic CBD as a Therapy for COVID-19
The study aim to test proof of concept of CBD treatment for efficacy and safety in patients suffering with mild COVID-19 infection. The CBD will be delivered via oil droplets not containing THC, compared to placebo.
- Trial name
- NCT04686539
- Testing
- CBD
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
COVID-19
A Study to Test BI 767551 in People With Mild to Moderate Symptoms of COVID-19
This study is open to adults with mild to moderate symptoms of COVID-19 (coronavirus disease). The purpose of this study is to find out whether a medicine called BI 767551 helps people with COVID-19.
- Trial name
- NCT04822701
- Testing
- BI 767551 intravenous, BI 767551 inhaled
- Where
- 5 sites in United States, Spain
- Volunteers
- 5 people
- Sponsor
- Boehringer Ingelheim
COVID-19
SHEN211 Tablets for the Treatment of Mild and Moderate Novel Corona Virus Infections (COVID-19)
Randomized, double-blind, placebo-controlled, multicenter phase II clinical study of SHEN211 tablets
- Trial name
- NCT06288893
- Testing
- SHEN211 Tablets
- Where
- China
- Volunteers
- 30 people
- Sponsor
- JKT Biopharma Co., Ltd.
Covid19
A Phase 2 Clinical Trial of MW33 Injection in Patients With COVID-19
This study is designed as a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the clinical efficacy and safety of MW33 injection in patients with mild or moderate COVID-19, and to evaluate its…
- Trial name
- NCT04627584
- Testing
- MW33 injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
COVID-19
Study to Evaluate the Effects of AT-527 in Non-Hospitalized Adult Patients With Mild or Moderate COVID-19
This randomized study evaluates the antiviral activity, safety, efficacy and pharmacokinetics of AT-527 versus a placebo in participants with mild or moderate coronavirus disease (COVID-19) who are not hospitalized.
- Trial name
- NCT04709835
- Testing
- AT-527
- Where
- 12 sites in Canada, Greece and 4 more
- Volunteers
- 104 people
- Sponsor
- Hoffmann-La Roche
Coronavirus Infections, Pneumonia, Viral
Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 Infection
The scientific community is in search for novel therapies that can help to face the ongoing epidemics of novel Coronavirus (COVID-19) originated in China in December 2019.
- Conditions
- Coronavirus Infections, Pneumonia, Viral, Dyspnea
- Trial name
- NoCovid (NCT04290858)
- Testing
- Nitric Oxide
- Sponsor
- Xijing Hospital
SARS-CoV2 Infection, COVID-19
IMM-BCP-01 in Mild to Moderate COVID-19
The primary objective of this study is to evaluate the safety and tolerability of intravenous (IV) IMM-BCP-01 in subjects with mild to moderate COVID-19 through Day 28.
- Trial name
- NCT05429021
- Testing
- IMM-BCP-01
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Immunome, Inc.
COVID - 19
EFFICACY OF COLCHICINE IN IMPROVING CLINICAL OUTCOMES IN PATIENTS WITH MILD TO MODERATE COVID-19 PNEUMONIA IN LAHORE: A RANDOMIZED CONTROL TRIAL
This study is for patients suffering from COVID-19 pneumonia (mild to moderate cases) ; especially in developing countries where expensive drugs are not available.
- Trial name
- Colchicine (NCT06847204)
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Zaeema Kanwal
Covid19
PHRU CoV01 A Trial of Triazavirin (TZV) for the Treatment of Mild-moderate COVID-19
A) Phase II: Early viral responses to triazavirin In hospitalised patients with mild-moderate COVID-19, in addition to standard of care therapy, treatment with triazavirin 250mg three times daily for five days, the slope of…
- Trial name
- PHRUCov01 (NCT04581915)
- Testing
- Triazavirin (Riamilovir)
- Where
- South Africa
- Volunteers
- 74 people
- Sponsor
- Wits Health Consortium (Pty) Ltd
COVID-19, Mild to Moderate
COVID-19 Study at the Russian Clinical and Research Center of Gerontology of the Pirogov RNRMU
This is a retrospective observational cohort study. About 1000 hospital charts of adult patients admitted to the hospital with mild-to-moderate COVID-19 from February to August 2020 were analyzed to evaluate the inflammatory…
- Trial name
- NCT05302947
- Testing
- Baricitinib Oral Tablet, Tocilizumab Injection, Netakimab
- Where
- 2 sites in Russia
- Volunteers
- 154 people
- Sponsor
- Pirogov Russian National Research Medical University
Nutrition, Healthy
Oral Nutritional Supplements in Treatment of Elderly Mild-to-Moderate COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has seriously threatened public health worldwide. Nutritional supplements may have a positive influence on the recovery of patients with viral infection.
- Trial name
- ONSITEMC (NCT05629975)
- Testing
- Oral Nutritional Supplements
- Volunteers
- 150 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
COVID-19
Non-inferiority Trial on Monoclonal Antibodies in COVID-19
Currently, 3 anti-SARS-CoV-2 monoclonal antibody products have received Emergency Use Authorizations from the Italian Medicines Agency (AIFA) for the treatment of mild to moderate COVID-19 in non hospitalized patients with…
- Trial name
- MANTICO (NCT05205759)
- Testing
- Bamlanivimab Etesevimab, Sotrovimab, Casirivimab-Imdevimab
- Where
- 20 sites in Italy
- Volunteers
- 319 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Covid19, SARS-CoV-2
Efficacy of Iodine Complex Against COVID-19 Patients
The objective of this study is to measure the effect of Iodine complex in treating the COVID-19 patients to clear viral load of SARS-CoV-2 along with reduction in severity of symptoms and length of hospitalization of patients…
- Conditions
- Covid19, SARS-CoV-2, Corona Virus Infection
- Trial name
- I-COVID-PK (NCT04473261)
- Testing
- Iodine Complex, Idoine Complex
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Sohaib Ashraf