Clinical trials: Mild to Moderate Dry Eye Disease
Dry Eye
Phase II Clinical Study to Evaluate the Efficacy of Multidose Lagricel® Ofteno Ophthalmic Solution as Treatment for Dry Eye Disease.
Phase II, comparative, controlled, multicenter, parallel group, open, randomized clinical study. The main outcome variable will be the Ocular Surface Disease Index (OSDI) questionnaire.
- Trial name
- PRO-037 (NCT04704531)
- Testing
- Sodium Hyaluronate Ophthalmic 0.4% one drop twice a day (BID), Sodium Hyaluronate Ophthalmic 0.4% one drop four times a day (QID), Sodium Hyaluronate Ophthalmic 0.4% Six times per day
- Where
- Mexico
- Volunteers
- 141 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Dry Eye, Meibomian Gland Dysfunction
To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern
MGD is a chronic, diffuse abnormality of the meibomian glands, commonly characterized by terminal duct obstruction and/or qualitative/quantitative changes in the glandular secretion.
- Trial name
- NCT05383612
- Testing
- Warm compresses, 3% Diquafosol Sodium Eye Drops
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dry Eye Disease
The Evaluation of the Transcutaneous Electrical Stimulation Medical Device's Safety and Effectiveness in Treating the Patients With Dry Eye Disease
The purpose of this study is to investigate the safety and effectiveness for applying the electrical stimulation transcutaneously around the eyes and peripheral nerves nearby.
- Trial name
- NCT05203796
- Testing
- Transcutaneous pulsed electrical stimulation (NuEyne 02)
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Nu Eyne Co., Ltd.
Dry Eye, Dry Eye Disease (DED)
A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.
The purpose of this randomized, controlled, multicenter study is to evaluate the safety and efficacy of TTAX03 in participants with mild to moderate DED. The primary question it aims to answer is if TTAX03 is safe.
- Conditions
- Dry Eye, Dry Eye Disease (DED), Dry Eye Disease With Severe Keratitis
- Trial name
- NCT06780306
- Testing
- TTAX03
- Where
- 9 sites in United States
- Volunteers
- 74 people
- Sponsor
- BioTissue Holdings, Inc
Dry Eye
Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye
The purpose of this study is to evaluate efficacy and safety of the ophthalmic solution PRO-148 in the ocular surface of patients with mild to moderate dry eye compared with ophthalmic solution Systane®
- Trial name
- NCT01657253
- Testing
- PRO-148, Systane
- Where
- Mexico
- Volunteers
- 183 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Dry Eye Syndrome
Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye
Background: Dry eye disease (DED) is a common condition causing burden on visual function and reducing quality of life. Corticosteroids and/or cyclosporine eye drops are able to improve DED symptoms, however, side effects of…
- Trial name
- DEDCO (NCT03074344)
- Testing
- XLHA+CoQ10, Hyaluronic acid (HA)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Dry Eye Disease (DED)
BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber
The purpose of this study is to evaluate the short-term effects (impact on tear film and dry eye symptoms) of the BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber (the device under investigation) in individuals…
- Trial name
- NCT07430735
- Testing
- BriTer Eyez Moisture Vue™ On Demand Disposable Moisture Chamber
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Rochester
Dry Eye
Microvascular and Inflammatory Responses of 0.05 Cyclosporine Eye Drop (II) in Treatment of Dry Eye
To explore the law of changes in ocular surface inflammation when 0.05% cyclosporine eye drops (II) is used to treat dry eye, 50 cases of mild to moderate dry eyes were included.
- Trial name
- NCT05131152
- Testing
- Cyclosporine, oculus keratograph, in vivo laser confocal microscopy, Functional slit lamp biomicroscopy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University