Clinical trials: Milk Intolerance
Lactose Intolerance
Effect of B.Bifidum 900791 Intake in Adult With Hypolactasia and Lactose Intolerance
Lactase is high in the newborn intestine, allowing him to digest the high amounts of lactose present in breastmilk. From weaning, lactase is genetically programmed to decrease, reaching residual levels in the adult.
- Trial name
- NCT03952988
- Testing
- Probiotic ice cream
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Lactose Intolerance
HYBRID: Hydrogen Breath Test in Lactose Digestion
The purpose of this study is to investigate the effect of a fermented infant formula on lactose digestion in lactose intolerant adults.
- Trial name
- HYBRID (NCT02703987)
- Testing
- Fermented infant milk formula, Non-fermented infant milk formula
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Lactose Intolerance
Perceived Lactose Intolerance
The goal of this study was to examine the effects of self-perceived lactose intolerance (SPLI) as it relates to calcium intake and specific health problems that have been attributed to reduced intake of calcium and foods from the…
- Trial name
- NCT01331265
- Where
- United States
- Volunteers
- 3,815 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Irritable Bowel Syndrome
Efficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS.
Irritable bowel syndrome (IBS) is a frequently encountered disorder. According to the Rome IV criteria, it is characterized by abdominal pain associated with a change in stool frequency or con-sistency, or with symptomatic…
- Trial name
- NCT05120752
- Testing
- FODMAP diet
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cow Milk Protein Allergy, Cow Milk Intolerance
Partially Hydrolysed Whey Based Formula in Differentiation Between Non IgE Gastrointestinal Cow's Milk Protein Allergy and Milk Intolerance
Partially hydrolysed whey based formula in differentiation between non IgE gastrointestinal cow's milk protein allergy and milk intolerance
- Trial name
- NCT07687797
- Testing
- partially hydrolysed whey based formula, amino acid based formula
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Lactose Intolerance
Lactose Intolerance in Infants With Gastrointestinal Disturbances
This study enrolled thirty infants who presented by GIT symptoms and their CoMiSS was ≥ 12. The patients were assessed upon presentation, after 2 weeks of receiving lactose free diet regimen and 2 weeks after rechallenging them…
- Trial name
- NCT06789068
- Testing
- lactose free regimen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Lactose Intolerance
Screening of Lactose Intolerance Among IBS Patients Diarrhea Dominant
This cross-sectional study aims to determine the prevalence of lactose intolerance among patients with chronic diarrhea, assess its correlation with age and gender, and evaluate common symptoms in affected patients.
- Trial name
- NCT06931379
- Volunteers
- 70 people
- Sponsor
- Assiut University
Lactose Intolerance
Evaluation of LacTEST for the Diagnosis of Hypolactasia in Adults and Elderly Patients Presenting With Clinical Symptoms of Lactose Intolerance
The purpose of this study is to evaluate both the impact of LacTEST on diagnostic thinking and on patient management, and its reproducibility (Test-Retest), for the diagnosis of hypolactasia in adults and elderly patients…
- Trial name
- NCT02636413
- Testing
- gaxilose, lactose
- Where
- 6 sites in Spain
- Volunteers
- 1 people
- Sponsor
- VenterPharma
Lactose Intolerance, Ulcerative Colitis
Amount of Lactose Causing Symptoms in People With Lactose Intolerance and Ulcerative Colitis
The hypothesis underlying this study is that failure to recognise the role of lactose intolerance among patients with ulcerative colitis has led to inappropriate dietary advice and treatment with drugs that contain lactose as a…
- Trial name
- NCT00403923
- Testing
- Lactose in water
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University Hospitals, Leicester
Lactose Intolerance
Evaluation of GIMate Handheld Hydrogen Breath Monitor for Diagnosis of Lactose Malabsorption
The goal of this study is to assess the performance of the Vivante Health GIMate Breathalyzer device in diagnosing lactose malabsorption.
- Trial name
- NCT04754724
- Testing
- GIMate, H2 Check
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vivante Health
Lactose Intolerance
Association Between Lactase Deficiency, and the Small Intestinal Microbiome in Adults.
The purpose of this study is to study the role of the enzyme (substance produced by the body that helps in a biochemical reaction like digestion in the body) responsible for digestion of lactose and the role of the gut bacteria…
- Trial name
- NCT03860051
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Indiana University
Breast Milk Protein Intolerance
Recruiting All Strictly Breast-fed Babies With Blood In Stool
Breast feeding is the most nutritious form of nourishment in infants and is recommended for at least the first four months of life. Breast fed infants may develop milk protein intolerance.
- Trial name
- NCT02745977
- Testing
- Dairy Free Diet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Lactose Intolerance
Modulation of Lactase Expression by a New PPARgamma Ligand in Duodenal Biopsies
This study is designed to assess the effect of a new PPARgamma modulator on the expression and activity of the lactase enzyme in human intestinal epithelial cells.
- Trial name
- NCT02902016
- Testing
- GED
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Lactose Intolerance, Lactose Intolerant
Milk for Diabetes Prevention
Individuals with lactase non-persistence (LNP; determined by a functional variant in the LCT gene [rs4988235, GG genotype]) are susceptible to lactose intolerance in adulthood due to deficiency of lactase, the enzyme which…
- Conditions
- Lactose Intolerance, Lactose Intolerant, Lactase Persistence, Pre-Diabetes
- Trial name
- NCT06513026
- Testing
- Lactose-Containing Milk, Lactose-Free Milk
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Albert Einstein College of Medicine
Lactose Intolerance
A Bifido Bacteria to Improve Lactose Digestion and Tolerance
We want to determine if feeding a bifido bacteria that readily digests lactose and galactooligosacharides improves lactose digestion and tolerance through alteration of the microbiome.
- Trial name
- NCT05668468
- Testing
- Bifidobacterium adolescentis IVS-1 capsule
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Milk Intolerance, Milk Hypersensitivity
Goat vs. Cow Milk Digestive Tolerance
The objective of this study is to assess to what extent goat's milk is better tolerated than cow's milk among individuals who report being intolerant to cow's milk, and, if so, to understand the underlying factors.
- Conditions
- Milk Intolerance, Milk Hypersensitivity, Cow Milk Protein Sensitivity
- Trial name
- DIGIGOAT (NCT07239856)
- Testing
- Cow milk, Goat Milk
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Lactose Intolerance
Effect of a Probiotic With High Beta-galactosidase Activity on Patients With Lactose Intolerance
Lactose intolerance is a chronic disease caused by the total/partial lack of lactase production. When lactose is not properly digest, it is consumed by the microbiota.
- Trial name
- PROBIOLAC (NCT05367453)
- Testing
- Tropical juice with probiotics (B.coagulans), a Tropical juice with no probiotics, lactase tablet
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Lactose Intolerance
Effect of a Combination of Lactase and L. Salivarius DSM 34078 in Individuals With Lactose Intolerance
The goal of this clinical trial is to test whether a new combination of lactase and bacterial strain (L. Salivarius DSM 34078) can provide longer lasting beneficial effects on lactose digestion and gastrointestinal symptoms…
- Trial name
- NCT06107088
- Testing
- Active 1, Active 2, Active 3
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- Novozymes A/S
Lactose Intolerance
Effect of a Standard Meal on the Pharmacokinetic Profile of RP-G28 in Healthy Adult Male and Female Subjects
Randomized, open-label, 2-period, 2-sequence, crossover study to evaluate the effect of a standard meal on the pharmacokinetic (PK) profile of orally administered RP-G28.
- Trial name
- RP (NCT03563846)
- Testing
- RP-G28
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ritter Pharmaceuticals, Inc.
Lactose Intolerance
Comparison of the Colonic Metabolism in Patients With Lactose Intolerance and Healthy Controls
Most people are born with the ability to digest lactose, a dissacharide consisting of β-D-glucose and β-D-galactose, because of the presence of lactase at the brush border of the small intestine.
- Trial name
- NCT02171403
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- KU Leuven