Clinical trials: Milk Intolerance
COW'S MILK ALLERGY
Polymerized Beta-lactoglobulin Comparative Immunoreactivity
Bovine β-lactoglobulin (Bos d 5) is an allergen from cow's milk with relevance to human health. We employed β-lactoglobulin polymerized using microbial transglutaminase as a model of study to identify whether protein…
- Trial name
- ImmuneBLG (NCT01589731)
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Lactose Intolerance
Effectiveness, Safety and Tolerability Study of RP-G28 for Symptoms Associated With Lactose Intolerance
This is a Phase 2 study designed to assess the ability of RP-G28 to improve lactose digestion and tolerance.
- Trial name
- NCT01113619
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Ritter Pharmaceuticals, Inc.
Irritable Bowel Syndrome, Lactose Intolerance
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION)
Irritable bowel syndrome (IBS) is a functional gastrointestinal disease. There is no well-defined pharmacological treatment. This clinical trial is a prospective, double-blind, two-armed randomized controlled, single-center…
- Conditions
- Irritable Bowel Syndrome, Lactose Intolerance, Lactose Malabsorption
- Trial name
- LION (NCT05100719)
- Testing
- alverine-citrate + simethicone and lactase
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- University of Pecs
Milk Hypersensitivity, Food Sensitivity
Evaluation of the Efficacy of a New Formula in Infants With Cow's Milk Protein Allergy
The aim of the study is to show the efficacy, tolerance and nutritional adequacy of a newly developed hydrolyzed rice formula in infants with a proven cow's milk protein allergy.
- Conditions
- Milk Hypersensitivity, Food Sensitivity, Protein Allergy
- Trial name
- Paradice (NCT01998074)
- Testing
- extensively hydrolyzed rice protein formula
- Where
- Belgium
- Sponsor
- United Pharmaceuticals
Lactose Intolerance
Effect of a Probiotic Formulation in Adults With Lactose Intolerance and Methanogenic Intestinal Overgrowth
Introduction: Lactose intolerance (LI) is characterized by specific gastrointestinal symptoms following the consumption of dairy products and lactose-containing foods, symptoms that may also be experienced by individuals with…
- Trial name
- LAC L-134/33 (NCT07652827)
- Testing
- Probiotic formulation
- Where
- Chile
- Volunteers
- 22 people
- Sponsor
- Universidad de Concepcion
Lactose Intolerance, Adult Type
Comparing the Gastric Transit of Commercial Milk and A2 Milk
Cow's milk contains two types of β-casein: A1 and A2. The μ-opioid peptide BCM-7 is released from A1 but not from A2. BCM-7 is associated with slower gastrointestinal transit and hence increased gastrointestinal transit times.
- Trial name
- NCT05658861
- Testing
- Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Purdue University
Impaired Glucose Tolerance, Type 2 Diabetes
Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
The purpose of this study is to determine if increased intake of low-fat milk products and calcium as part of a calorie restricted diet helps achieve a healthier body weight and body composition and decrease blood glucose levels…
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00564551
- Testing
- High dairy and calcium intake, Usual intake
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Calgary
Protein Intolerance
A2 GUM Post-Market Effectiveness Study
This is a post-market, real-life effectiveness study of A2 growing up milk on toddlers' gut comfort.
- Trial name
- NCT03698058
- Testing
- Toddler milk
- Where
- China
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cow's Milk Protein Allergy Protein Intolerance Failure to Thrive
Nutritional Evaluation of Infants Receiving Amino Acid-Based Formula
This study aims to evaluate the growth parameters and nutritional status of infants who are receiving amino acid-based formula due to cow's milk protein allergy or other medical indications.
- Trial name
- NCT07174999
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Assiut University
Chronic Diarrhea
Secondary Lactose Intolerance Due to Chronic Norovirus Infection
The objective of this study is to determine the prevalence of secondary lactose intolerance in renal transplant recipients (RTR) with chronic norovirus infection.
- Trial name
- NCT01840891
- Testing
- Lactose H2 breath test (LH2BT)
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Zurich
Lactose Intolerance
A Non-inferiority, Multicenter and Randomized, Multiple-Dose Study About a Treatment to Hypolactasia
The primary objective is to determine the compared clinical efficacy of Lactase Eurofarma (test drug), showing non-inferiority to Lactaid® (comparative drug) in the supportive treatment of lactose intolerance and to assess the…
- Trial name
- LAILAII (NCT01145586)
- Testing
- Lactase Oral Tablets
- Where
- 8 sites in Brazil
- Volunteers
- 140 people
- Sponsor
- Eurofarma Laboratorios S.A.
Lactose Intolerance, Irritable Bowel Syndrome
The Effects of Lactose Intolerance on Gastrointestinal Function and Symptoms in a Chinese Population
Lactose is a carbohydrate found in milk,and Lactase Deficiency (LD) is a condition in which the small intestine cannot digest this carbohydrate due to absent or insufficient amounts of lactase.Individuals with LD may be…
- Trial name
- NCT01286597
- Testing
- dietary restriction
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Premature; Infant, Light-for-dates
Re-feeding Gastric Residuals in Preterm Infants
The purpose of this study is to determine whether re-feeding of gastric residuals reduces the time needed to establish full enteral feedings in premature infants.
- Trial name
- NCT01420263
- Testing
- Re-feeding residuals, Fresh Feeding Breastmilk or Formula only
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Alabama at Birmingham
Lactose Intolerance
Effects Comparison of A1 and A2 Milk on Gastrointestinal Physiology, Symptoms and Cognitive Behavior
This is a single-site, double-blinded, randomized, controlled, 2X2 cross-over study aiming to compare effects of milk containing only A2 type beta casein versus milk containing both A1 and A2 beta casein proteins on the…
- Trial name
- NCT02406469
- Testing
- Oral consumption milk Tetra Pak
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
Hypolactasia
A Non-inferiority, Multicenter and Randomized, Single-Dose Study About a Treatment to Hypolactasia (LAILAI)
The study primary objective is to compare the clinical efficacy of two formulations in the supportive treatment of lactose intolerance.
- Trial name
- EF099 (NCT01145339)
- Testing
- Lactase
- Where
- 7 sites in Brazil
- Volunteers
- 140 people
- Sponsor
- Eurofarma Laboratorios S.A.
Milk Intolerance
Low-grade Inflammation and Gut Symptoms From A2 and Hydrolyzed A1 Milk
The aim of this study is to reveal how different forms of milk casein, lactose and moderate breakdown of proteins affect the symptoms that may arise from milk and markers of inflammation in volunteers receiving symptoms from…
- Trial name
- NCT05305391
- Testing
- Dietary intervention
- Where
- Finland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Turku
Lactose Intolerance, Adult Type
Testing the Capability of the Smart Underwear Device to Detect Increased Microbiome Activity Following Lactose Consumption
The goal of this Interventional study is to validate the Smart Underwear device's ability to detect lactose intolerance by comparing its results to self-reported symptoms in adult participants aged 18 and above, divided equally…
- Trial name
- NCT06724705
- Testing
- Lactose, Sucrose, Wear smart underwear
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Lactose Intolerance
Validation of a Home-screening Test for Lactose Intolerance
The hypothesis underlying this study is that whilst there is no home-screening test for lactose intolerance, this test would have significant value as lactose tolerance tests and breath hydrogen tests are expensive and time…
- Trial name
- NCT00844766
- Sponsor
- University Hospitals, Leicester
Prematurity, Light-For-Dates
Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants
In this proposed clinical trial, the investigators will randomize 80 very preterm (VPT) infants to receive either early (between day 4 and 7) or delayed (between day 10 and 14) fortification and determine if providing early…
- Conditions
- Prematurity, Light-For-Dates, Enteral Feeding Intolerance
- Trial name
- ENACT+ (NCT05525585)
- Testing
- Early HMF, Delayed HMF
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Lactose Intolerant, Lactose Malabsorption
Proper Dietary Management, Follow-up, and Lactase Enzyme Supplementation for Lactose Intolerance
Lactose intolerance (LI) is considered the clinical syndrome caused by lactose malabsorption (LM). It is possible to identify four causes of lactase deficiency defining four different types of LM: primary (genetic), secondary…
- Conditions
- Lactose Intolerant, Lactose Malabsorption, Lactose Intolerance
- Trial name
- NCT06773650
- Testing
- Completion of online survey
- Where
- Italy
- Volunteers
- 385 people
- Sponsor
- European Institute of Oncology