Clinical trials: Minimally Invasive Treatment
Colorectal Disorders, Surgery
Transverse Abdominus Plane Block Study
Study the effect of laparoscopic guided TAP block on opioid consumption and associated costs using a mixture of dexmedetomidine, dexamethasone, and ropivacaine versus Liposomal bupivacaine (Exparel®) in patients who undergo…
- Trial name
- TAP (NCT05216055)
- Testing
- Ropivacaine, Dexmedetomidine, Dexamethasone sodium phosphate, Normal saline, Liposomal bupivacaine
- Sponsor
- University of Colorado, Denver
Intracranial Hemorrhage
INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage
The primary objective of this multicenter single arm feasibility study is to provide an assessment of enrollment and follow up feasibility for this patient population being treated with the Apollo Minimally Invasive Surgical…
- Trial name
- NCT02654015
- Testing
- Apollo MIES, Medical Management
- Where
- 7 sites in United States
- Volunteers
- 50 people
- Sponsor
- J. Mocco
Colorectal Cancer
Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study
Natural orifice specimen extraction surgery (NOSES) has gained widespread recognition among scholars and has gradually been promoted and popularized around the world.
- Trial name
- NCT06350370
- Testing
- Natural orifice specimen extraction
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Benign Breast Nodules
Ultrasound-Guided Emulsification Therapy in the Clinical Treatment of Benign Breast Nodules
Background： Benign breast nodules are common breast diseases in women, including fibroadenomas, hyperplastic nodules, and other benign lesions.
- Trial name
- NCT07797257
- Testing
- CUSA Minimally Invasive Resection
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Minimally Invasive Surgical Technique, Open Flap Debridement
Evaluation of Gain In Clinical Attachment And Bone Levels After Treatment of Patients With Intra-bony Defects By Minimally Invasive Surgical Technique Versus Open Flap Debridement.
Hypothesis:The conventional surgical approach is to raise large flaps to completely and exceedingly expose the area of interest.
- Conditions
- Minimally Invasive Surgical Technique, Open Flap Debridement, Microsurgery
- Trial name
- NCT03570736
- Testing
- Minimal invasive surgical technique, Open Flap Debridement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stroke Hemorrhagic
DTI-guided Minimally Invasive Hematoma Evacuation for Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a devastating disease with high early mortality, unfavorable neurological outcomes, and high cost of care.
- Trial name
- GLAMOR (NCT05891509)
- Testing
- Minimally Invasive Hematoma Evacuation, Best Medical Therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongming Qiu
Surfactant Deficiency Syndrome Neonatal
deMISTify: The Impact of Ventilator Pressure Levels During Minimally Invasive Surfactant Therapy on Lung Aeration in Preterm Infants
Infants born preterm (before 36 weeks' gestation age) have immature lungs and struggle to breathe on their own. They are supported via respiratory machines like ventilators, as well as pharmaceutical aids like surfactant…
- Trial name
- deMISTify (NCT07522346)
- Testing
- Lung Recruitment Manoeuvre prior to Minimally Invasive Surfactant Therapy, Control (Minimally Invasive Surfactant Therapy)
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- Murdoch Childrens Research Institute
Hydrocephalus, Normal Pressure, Hydrocephalus
Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus
The eShunt System includes proprietary delivery componentry and the eShunt Implant, a permanent implant deployed in a minimally invasive, neurointerventional procedure.
- Trial name
- NCT05250505
- Testing
- eShunt Implant
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- CereVasc Inc
Rectal Cancer Stage I
Endoscopic (EID) Versus Surgical (TAMIS) Local Excision for Early Stage Rectal Cancer
In this clinical trial, we compare the endoscopic technique, endoscopic intermuscular dissection (EID), with the surgical technique, transanal minimally invasive surgery (TAMIS) for the treatment of early stage rectal cancer.
- Trial name
- ENSURE (NCT07846046)
- Testing
- Endoscopic Intermuscular Dissection (EID), Transanal Minimally Invasive Surgery (TAMIS)
- Where
- 19 sites in Netherlands
- Volunteers
- 246 people
- Sponsor
- Amsterdam UMC, location VUmc
Lung Atypical Carcinoid Tumor, Lung Neuroendocrine Neoplasm
Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung Cancer
This phase II trial studies how well stereotactic body radiation therapy with or without nivolumab works in treating patients with stage I-IIA non-small cell lung cancer or cancer that has come back.
- Conditions
- Lung Atypical Carcinoid Tumor, Lung Neuroendocrine Neoplasm, Lung Non-Small Cell Squamous Carcinoma, Minimally Invasive Lung Adenocarcinoma
- Trial name
- NCT03110978
- Testing
- Nivolumab, Stereotactic Body Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- M.D. Anderson Cancer Center
Periodontitis, Stage IV Periodontitis
Minimally Invasive Non-surgical Therapy for the Treatment of Splinted Stage IV Periodontitis
Conventional periodontal treatment typically involves a combination of non-surgical and surgical approaches, such as scaling and root planing, followed by flap surgery and guided tissue regeneration.
- Conditions
- Periodontitis, Stage IV Periodontitis, Minimally Invasive Treatment, Splints
- Trial name
- NCT06772506
- Testing
- Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%), Minimally invasive non-surgical technique with mini five and after five minimally invasive instrument plus splint
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Intracerebral Hemorrhage
Evaluating a Prototype CT Scan for ICH Evacuation
The aim of the project is to collect pre-procedural CT scans, intra-procedural post-evacuation scans as well as immediate post-procedural CT scans to evaluate and collect feedback of two Siemens prototypes: 1) perfusion prototype…
- Trial name
- ICH-CTP II (NCT07455201)
- Testing
- DynaCT Multiphase, DynaCT Sine Spin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Prostate Cancer
Safety and Security Evaluation of Patients Submitted to Minimally Invasive Radical Prostatectomy
This project aims to evaluate safety and security of patients submitted to minimally invasive radical prostatectomy, who received discharge from hospital in the same day of the surgery (Group I), on the 1st post-surgery day…
- Trial name
- NCT03674996
- Testing
- Same day discharge, Next-day discharge, 2-days discharge
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Barretos Cancer Hospital
Coronary Artery Disease
Administration of AdVEGF-All6A+ to Myocardium of Individuals With Diffuse CAD Via Minimally Invasive Surgery
The proposed Phase I/II clinical trial will be used to determine the safety and toxicity of direct administration of the vector AdVEGF-All6A+ to the ischemic myocardium and to generate preliminary evidence regarding whether…
- Trial name
- NCT01757223
- Testing
- AdVEGF-All6A+, AdNull
- Sponsor
- Weill Medical College of Cornell University
Gingival Recession
A Novel Vertical Y-shaped Tunnel Approach Versus Modified Coronally Advanced Tunnel Technique, for The Treatment of Miller Class I Gingival Recession
Recent plastic procedures have provided satisfactory results in the treatment of gingival recession but there is, presently, a greater need for procedure that cause less surgical morbidity as also provide improved results.
- Trial name
- NCT06453369
- Testing
- Y shaped Tunnel with Connective tissue graft
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- October 6 University
Respiratory Distress Syndrome
Minimally Invasive Surfactant Therapy Followed by CPAP (MISTCPAP) in Preterm Infants With RDS
There is a reducing incidence of pneumothorax, PIE and the combined outcome of death or BPD since the development of Surfactant therapy.
- Trial name
- MISTCPAP (NCT01723683)
- Testing
- Surfactant
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Periodontitis
Emdogain Minimally Invasive Surgical Technique
The aim of this controlled study is to assess the clinical outcomes and patient reported outcomes of using minimally invasive surgical procedure with Straumann Emdogain as an adjunct (test treatment) or without Straumann Emdogain…
- Trial name
- NCT02551770
- Testing
- Scaling and root planing, Scaling and root planing without Emdogain, Emdogain application
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG