Clinical trials: Minocycline
Acne Vulgaris
Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin
The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby…
- Trial name
- NCT00240513
- Testing
- Minocycline, Minocycline plus tretinoin
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Derm Research @ 888 Inc.
Acne
Administration of Oral Extended Release Minocycline for Assessment of Skin and Plasma Concentrations of Minocycline
The primary objective of this study is to evaluate the skin and plasma concentrations of minocycline in subjects undergoing treatment of acne vulgaris with oral extended release minocycline.
- Trial name
- NCT02695446
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BioPharmX, Inc.
Mild to Moderate Acne
Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate Acne
This is a clinical trial to compare the benefits and possible adverse events of two antibiotic treatments for mild to moderate acne.
- Trial name
- MXMIN-001 (NCT00988026)
- Testing
- Minocycline vs Lymecycline
- Where
- Mexico
- Volunteers
- 168 people
- Sponsor
- Darier
Facial Papulopustular Rosacea
A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea
The primary objectives of this study are to determine the efficacy and safety of FMX103 1.5% minocycline foam applied topically once daily for 12 weeks in the treatment of rosacea.
- Trial name
- NCT04608500
- Testing
- FMX103 minocycline foam 1.5%, Vehicle foam
- Where
- 46 sites in United States
- Volunteers
- 771 people
- Sponsor
- Vyne Therapeutics Inc.
Skin Infections (Acne)
Bioequivalence Minocycline Bioequivalence
The aim of the study is to compare the bioavailability of two medications containing 100 mg of minocycline in capsules to determine bioequivalence.
- Trial name
- NCT01755611
- Testing
- Minocycline 100mg
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontitis
Antibiotic Study for Dental Implants
This study is for people at least 21 years old who have signs of problems, like swollen gums and shrinking bones, by dental implants.
- Trial name
- NCT00662532
- Testing
- Minocycline HCl
- Where
- 4 sites in United States
- Volunteers
- 44 people
- Sponsor
- OraPharma
Healthy
Dermal Cumulative Irritant Patch Study
A 21-Day, Randomized, Controlled Study to Evaluate the Skin Irritation Potential of FMX-101 in Healthy Volunteers Using a Cumulative Irritant Patch Test Design
- Trial name
- NCT04064125
- Testing
- FMX-101
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vyne Therapeutics Inc.
Healthy
Dermal Phototoxicity Study
Dermal Safety study to determine the Phototoxicity Potential of FMX-101 4% in Healthy Volunteers
- Trial name
- NCT04070742
- Testing
- FMX101
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vyne Therapeutics Inc.
Antibiotic Resistant Bacteria
Effect of Minocycline & Amoxicillin on Antibiotic Resistant Bacteria and Indigenous Microbiotas
A randomised, open labelled study design is selected in order to determine the emergence and persistence of antibiotic resistant bacteria in humans and on the composition of the indigenous microbiotas at various body sites.
- Trial name
- ANTIRESDEV (NCT02030912)
- Testing
- 3 doses of amoxicillin daily for 7 days, 2 doses of minocycline daily for five days
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helperby Therapeutics Ltd
Acne Vulgaris
To Evaluate the Efficacy and Safety of Minocycline Hydrochloride Foam in the Treatment of Moderate-to-severe Acne Vulgaris
This is a randomized, multicenter, double-blind, vehicle-controlled, 2-arm study to evaluate the safety and efficacy in 12 weeks of FMX101 minocycline foam, 4%, compared to vehicle, in the treatment of subjects with moderate to…
- Trial name
- NCT04960930
- Testing
- FMX101
- Where
- 29 sites in China
- Volunteers
- 372 people
- Sponsor
- Cutia Therapeutics (Shanghai) Co., Ltd
Acne Vulgaris
BPX-01 Minocycline 1% Topical Gel for Reduction of Propionibacterium Acnes
This is a Phase 2a study which is being conducted in healthy volunteers in order to evaluate the comparative reduction of Propionibacterium acnes in-vivo following once daily topical administration of BPX-01 Minocycline 1%…
- Trial name
- NCT02709096
- Testing
- BPX-01, 1% Topical Gel, BPX-01 Vehicle Gel
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- BioPharmX, Inc.
Acne Vulgaris
A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.
A study comparing FCD105 to 3% minocycline foam, 0.3% adapalene foam and vehicle foam in patients ≥ 12 years old for the treatment of moderate-to-severe acne.
- Trial name
- NCT04104685
- Testing
- FCD105, 3% Minocycline Foam, 0.3% Adapalene Foam
- Where
- 35 sites in United States
- Volunteers
- 446 people
- Sponsor
- Vyne Therapeutics Inc.