Clinical trials: Minor Ischemic Stroke
Cryptogenic Transient Ischemic Attack and Minor Stroke
Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke
Retrospective study, single-center, on 171 patients, presented a cryptogenic TIA and Minor stroke. This study objective is to determine profitability of Holter 21 days for screening paroxystic ACFA / flutter in cryptogenic…
- Trial name
- HOLTER-21J (NCT03166969)
- Testing
- Holter 21 days
- Where
- France
- Volunteers
- 171 people
- Sponsor
- Versailles Hospital
Ischemic Stroke, Transient Ischemic Attack
Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the…
- Trial name
- TACAMINIS (NCT04738097)
- Testing
- Ticagrelor 90mg, Clopidogrel 75 mg
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Brain Ischemia, Transient Ischemic Attack
ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial
The objective of ESPRIT was to compare the efficacy and safety of mild anticoagulation or a combination treatment of aspirin and dipyridamole with the efficacy and safety of treatment with aspirin alone after cerebral ischemia of…
- Conditions
- Brain Ischemia, Transient Ischemic Attack, Arteriosclerosis
- Trial name
- NCT00161070
- Testing
- anticoagulation, aspirin and dipyridamole, aspirin alone
- Where
- Netherlands
- Volunteers
- 4,500 people
- Sponsor
- UMC Utrecht
Minor Ischemic Stroke
Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅳ
The purpose of this study is to evaluate the efficacy and safety of intravenous tenecteplase (0.25 mg/kg) compared with standard therapy in patients with acute ischemic stroke presenting with mild symptoms-defined as a National…
- Trial name
- TRACE Ⅳ (NCT06414499)
- Testing
- rhTNK-tPA, Control group (Aspirin combined with clopidogrel)
- Where
- China
- Volunteers
- 1,386 people
- Sponsor
- Beijing Tiantan Hospital
Transient Ischemic Attack
Lleida TIA Intervention Study
Having a transient ischemic attack (TIA) or a minor stroke is a real risk factor not only for early recurrent stroke but also for major extracranial vascular events.
- Trial name
- LLETIS (NCT04524078)
- Testing
- intensive integrated intervention care program
- Volunteers
- 100 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Ischemic Stroke
Ticagrelor Versus Cilostazol in Minor Ischemic Stroke or TIA
Along with the current clinical trial, the efficacy and safety of ticagrelor and aspirin administered within the first 24 hours of first-ever ischemic stroke compared to cilostazol and aspirin were assessed through NIHSS, mRS…
- Trial name
- NCT06196047
- Testing
- Ticagrelor 90 MG, Cilostazol 100 MG
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Ischemic Stroke, TIA
Treatment of Rivaroxaban Versus Aspirin for Non-disabling Cerebrovascular Events
Transient ischemic attack (TIA) or minor ischemic stroke has a high risk of early recurrent stroke. As the golden standard, aspirin effect modestly on acute ischemic stroke, and slightly increase the risk of intracerebral…
- Trial name
- TRACE (NCT01923818)
- Testing
- rivaroxaban, Aspirin
- Where
- China
- Volunteers
- 3,700 people
- Sponsor
- Xijing Hospital
Ischemic Stroke
Combining Aspirin With Ticagrelor or Clopidogrel in Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever minor stroke or TIA compared to 300 mg clopidogrel were assessed through NIHSS…
- Trial name
- NCT06591312
- Testing
- Ticagrelor 90 MG, Clopidogrel
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Transient Ischemic Attack, Minor Stroke
China Registry of Non-disabling Ischemic Cerebrovascular Events
The burden of non-disabling ischemic cerebrovascular events (NICE) is significantly increased. In order to achieve accurate risk stratification and effective treatments, developing new diagnostic, therapeutic, and prognostic…
- Trial name
- CR-NICE (NCT03079674)
- Testing
- observational only- no intervention
- Where
- 44 sites in China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Following Transient Ischemic Attack and Minor Stroke
Rationale: To date, anticoagulant therapy in acute stroke has also been limited by excess hemorrhagic events. The oral anticoagulant dabigatran is a novel agent, which has been shown to be associated with much lower intracranial…
- Trial name
- DATAS II (NCT02295826)
- Testing
- Dabigatran, Acetylsalicylic acid
- Where
- 6 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Ischemic Stroke
Balloon angiopLasty for Intracranial Atherosclerotic Minor Stroke/TIA
The objective of this study was to evaluate the safety and efficacy of early submaximal balloon angioplasty combined with medical therapy vs medical therapy alone for minor stroke/transient ischemic attack with intracranial…
- Trial name
- NCT06014723
- Testing
- Submaximal balloon angioplasty
- Where
- China
- Volunteers
- 416 people
- Sponsor
- Shouchun Wang, MD, PhD
Transient Ischaemic Attack, Stroke
Psychoeducation for Transient Ischaemic Attack and Minor Stroke
Transient Ischaemic Attack (TIA), also called 'ministroke' is characterised by shortlasting symptoms that generally do not cause permanent damage.
- Trial name
- OPTIMISM (NCT02550392)
- Testing
- Psychoeducation
- Where
- United Kingdom
- Volunteers
- 64 people
- Sponsor
- University of Nottingham
Minor Ischemic Stroke
Efficacy and Safety of Reperfusion Therapy for Minor Ischemic Stroke in China
Acute ischemic stroke is the most common type of stroke in China, accounting for 69.6% -72.8% of new strokes. In recent years, the proportion of mild stroke (NIHSS ≤ 5 points) has gradually increased, exceeding 50%, and the…
- Trial name
- NCT07322835
- Where
- China
- Volunteers
- 5,400 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Stroke, Acute
A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion
This trial will enroll patients that have been diagnosed with a transient ischemic attack (TIA) or minor stroke that has occurred within the past 12 hours.
- Trial name
- TEMPO-2 (NCT02398656)
- Testing
- Tenecteplase, Antiplatelet treatment
- Where
- 61 sites in Australia, Austria and 8 more
- Volunteers
- 1,274 people
- Sponsor
- University of Calgary
Stroke, Transient Ischemic Attack
Smartwatch-Guided Secondary Prevention After Stroke
After a first stroke or transient ischemic attack (TIA), the risk of recurrence is high in the weeks and months following the initial event.
- Trial name
- WATCH-STEP (NCT07640360)
- Testing
- Smartwatch-Guided Secondary Prevention after Stroke
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Lacunar Stroke, Stroke
Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial
The goal of this clinical trial is to learn if a combination of antiplatelet drugs works better than intravenous tissue plasminogen activator to treat small ischemic stroke (lacunar stroke).
- Conditions
- Lacunar Stroke, Stroke, Ischemic Stroke
- Trial name
- LACUNAR-tPA (NCT07111559)
- Testing
- rt-PA, DAPT
- Where
- 29 sites in Japan
- Volunteers
- 500 people
- Sponsor
- Nippon Medical School
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Treatment Following Transient Ischemic Attack and Minor Stroke
Objective: Demonstrate the safety of early use of dabigatran following TIA/minor stroke. Background: Although aggressive antithrombotic therapy has been shown to reduce the number of new ischemic events following stroke/TIA, this…
- Trial name
- DATAS (NCT01769703)
- Testing
- Dabigatran 110/150 mg BID
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University of Alberta
Transient Ischemic Attack, Non-disabling Stroke
Prevention of Ischemic Conditions in Non-disabling Stroke/Transient Ischemic Attack With Remote Ischemic Conditioning
This is a single-arm, open-labeled and phase II futility study. Application of Remote ischemic conditioning (RIC) as an adjunctive therapy to medication were involved in the study.
- Trial name
- PICNIC-ONE (NCT03004820)
- Testing
- Remote Ischemic Conditioning
- Where
- 4 sites in China
- Volunteers
- 167 people
- Sponsor
- Capital Medical University
Ischemic Stroke, TIA
Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events
Nondisabling cerebrovascular events represent the largest group of cerebrovascular disease with a high risk of recurrent stroke.
- Trial name
- ADANCE (NCT01924325)
- Testing
- Apixaban, Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xijing Hospital
Stroke, Physical Therapy Modality
Effectiveness of Telephysical Therapy as a Secondary Stroke Prevention Tool in Patients With Minor Stroke.
This study investigates the effectiveness of telephysiotherapy as a rehabilitation and secondary prevention tool in patients with minor stroke, TIA, or LACI, comparing an experimental group receiving tele-assisted aerobic and…
- Conditions
- Stroke, Physical Therapy Modality, Secondary Prevention, Physical Therapy Evaluation
- Trial name
- TPT-Stroke (NCT06780891)
- Testing
- Telephysical therapy, Educational session
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- University of Cadiz