Clinical trials: Miscarriage
Miscarriage
Management of Women With an Incomplete Miscarriage
Miscarriage is defined as the spontaneous loss of a pregnancy before 24 weeks' gestation, that is, before the fetal viability. The clinical signs of miscarriage are usually vaginal bleeding associated abdominal pain and cramping…
- Trial name
- NCT03148561
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Recurrent Miscarriage
Distinct Alterations in Gut Microbiota Composition Among Women of Reproductive Age With Elevated Homocysteine Levels.
The goal of this observational study is to test the alterations of gut microbiota composition among women of reproductive age with elevated homocysteine levels.
- Trial name
- NCT06001060
- Where
- China
- Volunteers
- 38 people
- Sponsor
- First People's Hospital of Hangzhou
Unexplained Recurrent Miscarriage and Recurrent Implantation Failure
A Preliminary Study About Unexplained Recurrent Miscarriage and Repeated Implantation Failure Patients Treated With Low-dose Lymphocyte Immunotherapy
Recurrent miscarriage(RM) and recurrent implantation failure (RIF) are clinical challenge for clinicians and patients who are desperate for a healthy child.The specific etiology contains chromosomal abnormalities, reproductive…
- Trial name
- immunotherapy (NCT03081325)
- Testing
- low-dose lymphocyte immunotherapy
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Nanjing University
Infertility (IVF Patients), Infertility Treatment
Ketorolac Use and Fresh Embryo Transfer Outcomes
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days…
- Conditions
- Infertility (IVF Patients), Infertility Treatment, Post-op Pain, Fresh Embryo Transfer
- Trial name
- NCT07185724
- Testing
- Ketorolac 30 mg IV
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jessica D. Kresowik
Recurrent Pregnancy Loss, Recurrent Miscarriage
A Multi-center, Placebo-controlled Study to Evaluate NT100 in Pregnant Women With a History of Unexplained Recurrent Pregnancy Loss (RPL)
This is a randomised, double blind, multi-center, placebo-controlled study of subcutaneous NT100 in pregnant women with a history of unexplained recurrent pregnancy loss.
- Trial name
- RESPONSE (NCT02156063)
- Testing
- NT100
- Where
- 19 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Nora Therapeutics, Inc.
Abortion
Comparative Psychiatric Problems Between First and Second Trimester Miscarriage
Description of the psychiatric impact of miscarriage on women.
- Trial name
- NCT06742632
- Testing
- Symptoms checklist-90
- Where
- Egypt
- Volunteers
- 155 people
- Sponsor
- Assiut University
Unexplained Recurrent Miscarriage
Hydroxychloroquine and Unexplained Recurrent Miscarriage
Recurrent miscarriage affects women of childbearing age worldwide. Vascular endothelial dysfunction and immunological impairment are associated with recurrent miscarriage To date, there is no effective or optimal therapeutic…
- Trial name
- NCT04228263
- Testing
- Hydroxychloroquine, Folic Acid, Low-dose aspirin
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Assiut University
Infertility Female, Recurrent Miscarriage
Study on the Association Between SXCI and RM and the Possible Genetic Mechanism
To determine whether there is higher incidence of skewed X chromosome inactivation(SXCI) in the recurrent miscarriage(RM) population compared with normal population, and verify the existing hypothesis of the possible genetic…
- Trial name
- NCT02504281
- Where
- China
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Care in Women With History of Recurrent Miscarriage
Nursing Counseling on Stress and Depression for Women With Recurrent Miscarriage
Recurrent miscarriage is a frustrating event for couples. The purpose of this randomized, controlled trial was to examine the effectiveness of nursing counseling on sleep quality, depression, stress, and social support in women…
- Trial name
- NCT04361747
- Testing
- nursing counseling
- Volunteers
- 62 people
- Sponsor
- National Cheng-Kung University Hospital
Arcuate Uterus
A Randomised Controlled Trial of Hysteroscopic Resection of Mild Septum/Arcuate Uteri.
At least 82 cases of recurrent miscarriage women with a diagnosis of arcuate uterus, confirmed by three-dimensional intra-vaginal sonography (3D-TVS) and hysteroscopy, will be recruited.
- Trial name
- NCT03384082
- Testing
- hysteroscopic treatment
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Recurrent Pregnancy Loss
The Epidemiology of Recurrent Spontaneous Abortion Associated With Thrombophilla
RSA is a multifactorial disorder resulting from genetic factors, anatomic factors, autoimmune disorders, endocrine dysfunction, thrombophilia, life style factors, and maternal infections.
- Trial name
- NCT02990390
- Where
- China
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Ovarian Reserve, Miscarriage, Recurrent
The Effect of the Ovarian Reserve on the Recurrent Pregnancy Loss
The purpose of this study is to determine whether ovarian reserve is related to recurrent pregnancy loss
- Trial name
- NCT03009370
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Chronic Endometritis, in Vitro Fertilization
Chronic Endometritis and IVF
Background: Embryo quality is known to be a very important determinant to predict the implantation and pregnancy rate in IVF patients, however, the role of uterine integrity or endometrial receptivity cannot be overlooked.
- Trial name
- CEIVF (NCT02646930)
- Testing
- Endometrial biopsy
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- Duke University
Early Pregnancy Loss
Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy Loss
A prospective cohort study to explore the optimal time interval between mifepristone and misoprostol administration for medical management of early pregnancy loss.
- Trial name
- TIME (NCT07506512)
- Testing
- 200mg mifepristone and 800mg misoprostol
- Volunteers
- 1,000 people
- Sponsor
- University of Pennsylvania
Infertility, Endometritis
Chronic Endometritis in Patients With Recurrent Miscarriages or Repeated Implantation Failures in In-vitro Fertilization
Chronic endometritis is a persistent inflammation of the endometrium. Chronic endometritis is asymptomatic or little symptomatic.
- Conditions
- Infertility, Endometritis, Abortion, Spontaneous
- Trial name
- NCT01762098
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Clinique Ovo
Infertility, Implantation Failure
ISM1 Versus EmbrioGen Media for Embryo Culture With Previous Failure Implantation in ART Treatments
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689454
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Miscarriage, Recurrent
Use of Cyclosporin A for the Treatment of Recurrent Miscarriage
The purpose of this study is to determine whether Cyclosporin A (CsA) - an immunosuppressant drug - in early pregnancy will reduce the risk of miscarriage in women who had a history of unexplained recurrent miscarriages, as…
- Trial name
- NCT02706470
- Testing
- Cyclosporin A, Dydrogesterone
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Threatened Miscarriage
Vaginal Progesterone for Treatment of Threatened Miscarriage
The purpose of the study is to assess the efficacy of vaginal micronized progesterone in the treatment of threatened miscarriage.
- Trial name
- VPM (NCT02690129)
- Testing
- Vaginal Progesteron
- Where
- Egypt
- Volunteers
- 290 people
- Sponsor
- Omar Mamdouh Shaaban
Infertility, Female
Immediate Ambulation Versus Short-time Bed Rest in Sub-fertile Women Undergoing Embryo Transfer
Bed rest after embryo transfer (ET) has been clinically advised without robust scientific evidence. In investigators' unit, post ET instructions are given immediately after ET to sub-fertile women while lying in bed.
- Trial name
- NCT05148624
- Testing
- embryo transfer
- Where
- United Arab Emirates
- Volunteers
- 156 people
- Sponsor
- Dubai Fertility Center
Threatened Miscarriage
Non-interventional Study of Therapy for Threatened Miscarriage
Study the efficacy and safety of therapy for threatened miscarriage with medicinal products Utrogestan (micronized progesterone), 200 mg capsules (Besins Healthcare SA, Belgium), and Duphaston (Dydrogesterone), 10 mg coated…
- Trial name
- NCT03309735
- Testing
- Micronized progesterone, Dydrogesterone
- Where
- 17 sites in Russia
- Volunteers
- 1,241 people
- Sponsor
- Besins Healthcare