Clinical trials: Miscarriages
Miscarriage, Grief
Couples Miscarriage Healing Project:Randomized Trial
This is a randomized trial of three caring based interventions to see if we can help couples heal after miscarriage. All three are based on Swanson's theory of caring and Meaning of Miscarriage Model.
- Conditions
- Miscarriage, Grief, Pregnancy Loss
- Trial name
- NCT00194844
- Testing
- Nurse Caring, Self Caring, Combined Caring
- Where
- United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hyperinsulinemia, Miscarriages
Maternal Lifestyle and Neonatal Hypoglycemia
tPA has a pivotal role in placentation, mediationg activation of growth factors, such as vascular endothelial growth factor and brain-derived neurotrophic factor, degradation of extracellular matrix and basement membrane…
- Conditions
- Hyperinsulinemia, Miscarriages, Pregnancy, Sedentary Lifestyle
- Trial name
- NCT01409382
- Testing
- Daily brisk walking plus a carbohydrate-restricted diet
- Where
- Brazil
- Volunteers
- 480 people
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
IVF, Embryo Loss
The Use of High Concentration Hyaluronic Acid (HA) Transfer Medium in Repeated Implantation Failure (RIF) Patients
This is a pilot study with the aim to investigate the beneficial effect of bicarbonate buffered medium containing hyaluronan and recombinant human albumin (EmbryoGlue®, Vitrolife) in patients with documented repeated implantation…
- Conditions
- IVF, Embryo Loss, Miscarriage, Recurrent
- Trial name
- RIFLE (NCT04709796)
- Testing
- EmbryoGlue®, Vitrolife, Conventional Transfer
- Where
- Belgium
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Missed Abortion
Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage
The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of first trimester missed miscarriage.
- Trial name
- NCT02686840
- Testing
- sublingual misoprostol, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Fibroid, Miscarriage in First Trimester
Fibroids and the Risk of Miscarriage: a Prospective Observational Study in an Early Pregnancy Population
The aim of this observational study is to whether fibroids increase the risk of miscarriage in women in our early pregnancy population.
- Conditions
- Fibroid, Miscarriage in First Trimester, Miscarriage in Second Trimester
- Trial name
- FiRM (NCT06986616)
- Where
- United Kingdom
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Recurrent Pregnancy Loss
Prospective Recurrent Pregnancy Loss Registry
The purpose of this Registry is to prospectively collect data of Recurrent Pregnancy Loss (RPL) patients attending the specialized care centre at the BC Women's Hospital, in order to evaluate investigation practices, treatment…
- Trial name
- NCT05989178
- Testing
- Data Registry
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- University of British Columbia
Incomplete Miscarriage
Effectiveness of Hysteroscopy in the Treatment of Intrauterine Trophoblastic Retentions
The purpose of this study of is to compare subsequent fertility rates between hysteroscopy and aspirative curettage in the surgical treatment of incomplete spontaneous abortion
- Trial name
- HY-PER (NCT02201732)
- Testing
- Hysteroscopy, Curettage
- Where
- France
- Volunteers
- 577 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
First Trimester Abortion
Unexplained Early Miscarriage : Role and Prevalence of Lower Genital Tract Infections
The study group included 910 women who attended Fayoum university hospital gynecology outpatient clinic for postabortive evaluation.
- Trial name
- NCT03413774
- Testing
- vaginal swab
- Where
- Egypt
- Volunteers
- 1,850 people, healthy volunteers welcome
- Sponsor
- Cairo University
Miscarriage
Remnants of Conception After Suction Evacuation of Missed Abortion
All women admitted for surgical evacuation of missed abortion after failure of medical treatment from June 2016 underwent transvaginal sonography immediately after completion of the procedure as judged by the operator to ensure…
- Trial name
- NCT03813849
- Testing
- Sonographic examination of uterus after surgical evacuation
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- University of Alexandria
Pregnancy, Spontaneous Abortions
Study of the Best Blastocyst Post Transfer by aCGH
An Observational, blind and prospective study of Preimplantational Aneuploidy Screening by aCGH in Trophectoderm Biopsy
- Conditions
- Pregnancy, Spontaneous Abortions, Stillbirth
- Trial name
- NCT01664546
- Testing
- Trophectoderm biopsy
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- University of Buenos Aires
Threatened Miscarriage
Evaluation of Serum Levels of C Reactive Protein (CRP) and Its Correlation With Fetal Ultrasound Parameters in the Prediction of Threatened Miscarriage in the First Trimester
The goal of this observational study is to evaluate and compare in pregnant women with threatened miscarriage in the first trimester.
- Trial name
- NCT06011057
- Testing
- Serum C reactive protein (CRP) level, Ultrasound
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Retained Products of Conception
Removal of Intrauterine Retained Products of Conception (RPOC) After Miscarriage Guided by Hysteroscopy Trial. A Randomized Controlled Trial.
Rationale: Elective immediate dilation and curettage (D\&C) for miscarriage is associated with the occurrence of intrauterine adhesions (IUA). IUAs may be associated with subsequent subfertility and premature birth.
- Trial name
- RIGHT (NCT04804332)
- Testing
- Operative hysteroscopy, Expectant management
- Where
- Belgium
- Volunteers
- 244 people
- Sponsor
- University Hospital, Ghent
Maternal Care Patterns, Pregnancy Related
Cash Benefits and Reproductive/Perinatal Health
During the first two years of the COVID-19 pandemic, the City of Chelsea, Massachusetts held a lottery to allocate cash benefits to its residents for ten months.
- Conditions
- Maternal Care Patterns, Pregnancy Related, Miscarriage
- Trial name
- NCT05782660
- Testing
- Cash Benefit, No Cash Benefit
- Where
- United States
- Volunteers
- 3,615 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Recurrent Miscarriage, Infertility
EmbryoGen/ Blastgen for Couples With Implantation Problems or Previous Miscarriage
EmbryoGen and BlastGen contain the cytokine growth factor Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), which has been documented to give significant benefit to this difficult group of patients.
- Trial name
- BlastGen (NCT02305420)
- Testing
- EmbryoGen/ BlastGen media, Standard Cook sequential media
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- FertilitySA
Miscarriage, Recurrent, Infertility
The Role of NLRP Gene Family (NLRP1~14) in Recurrent Miscarriage and Infertility
Development of mole was not associated with segregation of mutated NLRP7 allele in the haploid oocyte. We hypothesize NLRP7 is a maternal factor involved in regulating early embryo development or embryo-uterine interaction.
- Trial name
- NCT04141618
- Where
- Taiwan
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Circulating Cell Free Fetal DNA, Intrauterine Fetal Demise
The Use of Cell Free Fetal DNA in the Maternal Blood in the Evaluation of Intrauterine Fetal Demise and Miscarriage
Women presenting to Washington Hospital Center with fetal loss would be offered participation in the study. The objective is to determine if ccffDNA obtained from maternal blood is present in the setting of missed abortion or…
- Conditions
- Circulating Cell Free Fetal DNA, Intrauterine Fetal Demise, Miscarriage
- Trial name
- NCT01916928
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Threatened Miscarriage
Vaginal Progesterone for Treatment of Threatened Miscarriage
The purpose of the study is to assess the efficacy of vaginal micronized progesterone in the treatment of threatened miscarriage.
- Trial name
- VPM (NCT02690129)
- Testing
- Vaginal Progesteron
- Where
- Egypt
- Volunteers
- 290 people
- Sponsor
- Omar Mamdouh Shaaban
Retained Products of Conception, Miscarriage
A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV
The goal of this observational study is to learn about the therapeutic effects of the conservative treatment approach on pepole with retained products of conception (RPOC) and Enhanced myometrial vascularity (EMV).
- Conditions
- Retained Products of Conception, Miscarriage, Conservative Management
- Trial name
- NCT06862089
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Miscarriage
Sublingual Misoprostol In Medical Treatment of First Trimester Missed Miscarriage
The aim of this work is to compare the effectiveness of sublingual misoprostol 400 mcg versus 800 mcg for medical treatment of the first trimester missed miscarriage.
- Trial name
- NCT05103098
- Testing
- misoprostol 400 mcg, misoprostol 800 mcg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- hany farouk