Clinical trials: Mitochondrial Alteration, open to volunteers
Menopause, Exercise Adaptation
The Effects of Menopausal Status, Isoflavone Supplementation and Training on Cardiometabolic Function Women
The goal of this clinical trial is to investigate the role of estrogen and isoflavone supplementation in exercise-induced cellular signaling and cardiometabolic adaptations in premenopausal and postmenopausal women.
- Conditions
- Menopause, Exercise Adaptation, Mitochondrial Alteration, Vascular Function in Healthy Volunteers
- Trial name
- EXISO (NCT07878741)
- Testing
- Red Clover Isoflavone Supplementation, Supervised exercise training
- Where
- 2 sites in Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Schizophrenia and Related Disorders, Mitochondrial Alteration
MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
The goal of this double-blind, placebo-controlled randomized clinical trial is to test the effect of 12 weeks of orally administered MitoQ (mitoquinol mesylate) supplementation on cognition in 50 people with early phase…
- Conditions
- Schizophrenia and Related Disorders, Mitochondrial Alteration, Cognitive Impairment
- Trial name
- NCT06191965
- Testing
- MitoQ
- Where
- 3 sites in United States, Switzerland
- Volunteers
- 100 people
- Sponsor
- Mclean Hospital
Infertility, Female, Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, Insulin Resistance, Primary Ovarian Insufficiency
- Trial name
- POMODORI (NCT06167135)
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis
Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA
The main research hypothesis is that alterations in the communication between the endoplasmic reticulum (ER) and the mitochondria at contact sites called mitochondria-associated membranes (MAMs) occurs in different hepatic cell…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, Sleeve Gastrectomy, Gastric Bypass Surgery
- Trial name
- MAMBA (NCT06868992)
- Testing
- Bariatric surgery (Sleeve Gastrectomy or Gastric Bypass)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon